scholarly journals Polymer dual ring resonators for label-free optical biosensing using microfluidics

2013 ◽  
Vol 49 (30) ◽  
pp. 3095 ◽  
Author(s):  
Muhammad H. M. Salleh ◽  
Andrew Glidle ◽  
Marc Sorel ◽  
Julien Reboud ◽  
Jonathan M. Cooper
Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3335
Author(s):  
Luca Tramarin ◽  
Carlos Angulo Barrios

A design study of a nanostructured two-dimensional plasmonic crystal based on aluminum and polymeric material for label-free optical biosensing is presented. The structure is formed of Al nanohole and nanodisk array layers physically separated by a polymeric film. The photonic configuration was analyzed through finite-difference time-domain (FDTD) simulations. The calculated spectral reflectance of the device exhibits a surface plasmon polariton (SPP) resonance feature sensitive to the presence of a modeled biolayer adhered onto the metal surfaces. Simulations also reveal that the Al disks suppress an undesired SPP resonance, improving the device performance in terms of resolution as compared to that of a similar configuration without Al disks. On the basis of manufacturability issues, nanohole diameter and depth were considered as design parameters, and a multi-objective optimization process was employed to determine the optimum dimensional values from both performance and fabrication points of view. The effect of Al oxidation, which is expected to occur in an actual device, was also studied.


2018 ◽  
Vol 10 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Qingming Zhu ◽  
Yong Zhang ◽  
Ciyuan Qiu ◽  
Xinhong Jiang ◽  
Yanping Yu ◽  
...  
Keyword(s):  

Chemosensors ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 119
Author(s):  
Paula Martínez-Pérez ◽  
Salvador Ponce-Alcántara ◽  
Nieves Murillo ◽  
Ana Pérez-Márquez ◽  
Jon Maudes ◽  
...  

Polymeric nanofiber matrices are promising structures to develop biosensing devices due to their easy and affordable large-scale fabrication and their high surface-to-volume ratio. In this work, the suitability of a polyamide 6 nanofiber matrix for the development of a label-free and real-time Fabry–Pérot cavity-based optical biosensor was studied. For such aim, in-flow biofunctionalization of nanofibers with antibodies, bound through a protein A/G layer, and specific biodetection of 10 µg/mL bovine serum albumin (BSA) were carried out. Both processes were successfully monitored via reflectivity measurements in real-time without labels and their reproducibility was demonstrated when different polymeric nanofiber matrices from the same electrospinning batch were employed as transducers. These results demonstrate not only the suitability of correctly biofunctionalized polyamide 6 nanofiber matrices to be employed for real-time and label-free specific biodetection purposes, but also the potential of electrospinning technique to create affordable and easy-to-fabricate at large scale optical transducers with a reproducible performance.


2009 ◽  
Author(s):  
Hongying Zhu ◽  
Ian M. White ◽  
Jonathan D. Suter ◽  
John Gohring ◽  
Xudong Fan
Keyword(s):  

2012 ◽  
Vol 24 (23) ◽  
pp. OP148-OP152 ◽  
Author(s):  
Yueh-Chun Lai ◽  
Hsin-Cheng Lee ◽  
Shu-Wen Kuo ◽  
Cheng-Kuang Chen ◽  
Hsieh-Ting Wu ◽  
...  

Author(s):  
Mi Kyoung Park ◽  
Jessie Quah Yiying ◽  
Jack Sheng Kee ◽  
Junfeng Song ◽  
Linus Tzu-Hsiang Kao ◽  
...  
Keyword(s):  

2014 ◽  
Vol 53 ◽  
pp. 178-186 ◽  
Author(s):  
Régis Méjard ◽  
Hans J. Griesser ◽  
Benjamin Thierry

2017 ◽  
Vol 419 ◽  
pp. 235-240 ◽  
Author(s):  
Monica Terracciano ◽  
Vardan Galstyan ◽  
Ilaria Rea ◽  
Maurizio Casalino ◽  
Luca De Stefano ◽  
...  

2010 ◽  
Vol 18 (20) ◽  
pp. 20638 ◽  
Author(s):  
Shinyoung Lee ◽  
Seok Chan Eom ◽  
Jee Soo Chang ◽  
Chul Huh ◽  
Gun Yong Sung ◽  
...  

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