An easy access to fluoroalkanes by deoxygenative hydrofluorination of carbonyl compounds via their tosylhydrazones

2013 ◽  
Vol 49 (21) ◽  
pp. 2154 ◽  
Author(s):  
Arvind K. Yadav ◽  
Vishnu P. Srivastava ◽  
Lal Dhar S. Yadav
Keyword(s):  
Carbonyl Compounds ◽  
Easy Access

Facile nucleophilic substitution of sulfonyl oxime ethers: an easy access to oxime ethers, carbonyl compounds and amines

2010 ◽  
Vol 46 (41) ◽  
pp. 7822 ◽  
Author(s):  
Sundae Kim ◽  
Nurul Ain Bte Kamaldin ◽  
Sol Kang ◽  
Sunggak Kim
Keyword(s):  
Nucleophilic Substitution ◽  
Carbonyl Compounds ◽  
Easy Access

ChemInform Abstract: An Easy Access to Fluoroalkanes by Deoxygenative Hydrofluorination of Carbonyl Compounds via Their Tosylhydrazones.

ChemInform ◽  
2013 ◽  
Vol 44 (25) ◽  
pp. no-no
Author(s):  
Arvind K. Yadav ◽  
Vishnu P. Srivastava ◽  
Lal Dhar S. Yadav
Keyword(s):  
Carbonyl Compounds ◽  
Easy Access

scholarly journals Fe(OTf) 3 -catalysed Friedel–Crafts reaction of benzenoid arenes with α,β-unsaturated carbonyl compounds: easy access to 1,1-diarylalkanes

2017 ◽  
Vol 4 (10) ◽  
pp. 170748 ◽  
Author(s):  
Aditya Bhattacharya ◽  
Pushpendra Mani Shukla ◽  
Biswajit Maji
Keyword(s):  
Reaction Mechanism ◽  
Cinnamic Acid ◽  
Efficient Method ◽  
Carbonyl Compounds ◽  
Acid Ester ◽  
Easy Access ◽  
Alkylation Reaction ◽  
Isotopic Labelling ◽  
Isotopic Labelling Experiments

A simple and efficient method for the synthesis of 1,1-diarylalkanes via the Friedel–Crafts-type alkylation reaction of electron-rich arenes with cinnamic acid ester derivatives or chalcones is reported. Iron triflate has been found to be the best catalyst for the Friedel–Crafts-type alkylation reaction with α,β-unsaturated carbonyl compounds. This reaction afforded β,β-diaryl carbonyl compounds in good yields (65–93%) and with excellent regioselectivities. Remarkably, this method is also compatible with a variety of indoles to provide 3-indolyl-aryl carbonyl compounds in excellent yields. Great efforts have been made to deduce a plausible reaction mechanism based on isotopic labelling experiments.

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