Determination of triclocarban in aquatic plants by using SPE combined with HPLC-ESI-MS/MS

2014 ◽  
Vol 6 (7) ◽  
pp. 2227-2232 ◽  
Author(s):  
Hong-Hao Miao ◽  
Yi-Nan Wang ◽  
Ru-Song Zhao ◽  
Wei-Lin Guo ◽  
Xia Wang ◽  
...  
Keyword(s):  
Aquatic Plants ◽  
Analytical Method ◽  
Esi Ms ◽  
Homogenate Extraction ◽  
Reliable Analytical Method

A convenient and reliable analytical method was developed for determination of antibacterial triclocarban in aquatic plants based on homogenate extraction, SPE clean-up, and HPLC-ESI-MS/MS determination.

Determination of morphine and its metabolites in the biological samples: an updated review

Bioanalysis ◽  
2020 ◽  
Vol 12 (16) ◽  
pp. 1161-1194
Author(s):  
Roghayeh Amini ◽  
Elaheh Rahimpour ◽  
Abolghasem Jouyban
Keyword(s):  
Analytical Method ◽  
Biological Samples ◽  
Opioid Analgesic ◽  
Individual Variability ◽  
Active Metabolites ◽  
Analytical Research ◽  
Reliable Analytical Method ◽  
Selection Of

Morphine (MO) as an opioid analgesic is used for the treatment of moderate-to-severe pains, particularly cancer-related pains. Pharmacologic studies on MO are complicated due to drugs binding to the protein or metabolization to active metabolites, and even inter-individual variability. This necessitates the selection of a reliable analytical method for monitoring MO and the concentrations of its metabolites in the biological samples for the pharmacokinetic or pharmacodynamic investigations. Therefore, this study was conducted to review all the analytical research carried out on MO and its metabolites in the biological samples during 2007–2019 as an update to the study by Bosch et al. (2007).

scholarly journals Determination of Pharmaceutical Residues by UPLC-MS/MS Method: Validation and Application on Surface Water and Hospital Wastewater

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Bui Van Hoi ◽  
Cam-Tu Vu ◽  
Lan-Anh Phung-Thi ◽  
Thao Thi Nguyen ◽  
Phuong Thanh Nguyen ◽  
...  
Keyword(s):  
Surface Water ◽  
Analytical Method ◽  
Limit Of Detection ◽  
Solid Phase ◽  
Multiple Reaction Monitoring ◽  
Hospital Wastewater ◽  
Esi Ms ◽  
Pharmaceutical Residues ◽  
Detection Frequency

In this study, an analytical method for the simultaneous determination of 7 major pharmaceutical residues in Vietnam, namely, carbamazepine, ciprofloxacin, ofloxacin, ketoprofen, paracetamol, sulfamethoxazole, and trimethoprim, in surface water and hospital wastewater has been developed. The method includes enrichment and clean-up steps by solid phase extraction using mix-mode cation exchange, followed by identification and quantification using an ultrahigh-performance liquid chromatography and tandem mass spectrometry and employing electrospray ionization (UPLC-ESI-MS/MS). Seven target compounds were separated on the reversed phase column and detected in multiple reaction monitoring (MRM) mode within 6 minutes. The present study also optimized the operating parameters of the mass spectrometer to achieve the highest analytical signals for all target compounds. All characteristic parameters of the analytical method were investigated, including linearity range, limit of detection, limit of quantification, precision, and accuracy. The important parameter in UPLC-ESI-MS/MS, matrix effect, was assessed and implemented via preextraction and postextraction spiking experiments. The overall recoveries of all target compounds were in the ranges from 55% to 109% and 56 % to 115% for surface water and hospital wastewater, respectively. Detection limits for surface water and hospital wastewater were 0.005–0.015 µg L−1 and 0.014–0.123 µg L−1, respectively. The sensitivity of the developed method was allowed for determination of target compounds at trace level in environmental water samples. The in-house validation of the developed method was performed by spiking experiment in both the surface water and hospital wastewater matrix. The method was then applied to analyze several surface water and hospital wastewater samples taken from West Lake and some hospitals in Vietnam, where the level of these pharmaceutical product residues was still missed. Sulfamethoxazole was present at a high detection frequency in both surface water (33% of analyzed samples) and hospital wastewater (81% of analyzed samples) samples.

Determination of Sterigmatocystin in Infant Cereals from Hangzhou, China

2016 ◽  
Vol 99 (5) ◽  
pp. 1273-1278 ◽  
Author(s):  
Shaoying Liu ◽  
Jicai Fan ◽  
Xihui Huang ◽  
Quan Jin ◽  
Guonian Zhu
Keyword(s):  
Electrospray Ionization ◽  
Analytical Method ◽  
Diode Array ◽  
Tandem Ms ◽  
Diode Array Detection ◽  
Simple Method ◽  
Esi Ms ◽  
Array Detection ◽  
Ionization Mode

Abstract A simple method was developed for the determination of sterigmatocystin in infant cereals. The method consists of a quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction approach and cleanup with an SPE HLB cartridge. After purification for separation and quantification of sterigmatocystin, HPLC with UV detection and diode-array detection (DAD) was used at sterigmatocystin levels >10 μg/kg, whereas ultra-performance LC with electrospray ionization (ESI) and tandem MS (MS/MS) was used at levels <10 μg/kg. The compound was determined by UV-DAD at 325 nm and by ESI-MS/MS in the positive ionization mode. Good r2 values (≥0.99) were found with both UV-DAD and ESI-MS/MS, and satisfactory recoveries (84.8–96.2%) of sterigmatocystin in infant cereals were demonstrated, with RSD values ≤11.43%. The developed analytical method was used for the determination of sterigmatocystin in infant cereals from Hangzhou, China.

An optimized method based on MAE-SPE-GC-MS for the analysis of thirteen PBDEs in airborne particles

2014 ◽  
Vol 6 (24) ◽  
pp. 9658-9666 ◽  
Author(s):  
X. Li ◽  
X. M. Li ◽  
X. X. Yang ◽  
Q. Li ◽  
B. Huang ◽  
...  
Keyword(s):  
Glass Fibre ◽  
Analytical Method ◽  
Polybrominated Diphenyl Ethers ◽  
Airborne Particles ◽  
Atmospheric Particulates ◽  
Diphenyl Ethers ◽  
Fine Glass ◽  
Reliable Analytical Method

An efficient and reliable analytical method has been developed for the determination of polybrominated diphenyl ethers (PBDEs) in atmospheric particulates collected by ultra-fine glass fibre filters.

A rapid analytical method for characterization and simultaneous quantitative determination of phytoconstituents in Piper betle landraces using UPLC-ESI-MS/MS

2014 ◽  
Vol 6 (18) ◽  
pp. 7349 ◽  
Author(s):  
Renu Pandey ◽  
Preeti Chandra ◽  
Mukesh Srivastva ◽  
K. R. Arya ◽  
Praveen K. Shukla ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Analytical Method ◽  
Piper Betle ◽  
Esi Ms

Simultaneous determination of chlorite, chlorate, perchlorate and bromate in ozonated saline by using IC-MS

2020 ◽  
Vol 12 (48) ◽  
pp. 5916-5921
Author(s):  
Xiuzhen Yin ◽  
He Cui ◽  
Sa Li ◽  
Shuyan Niu
Keyword(s):  
Mass Spectrometry ◽  
Simultaneous Determination ◽  
Ion Chromatography ◽  
Analytical Method ◽  
Triple Quadrupole ◽  
Quadrupole Mass ◽  
Triple Quadrupole Mass Spectrometry ◽  
Quadrupole Mass Spectrometry ◽  
Reliable Analytical Method

A simple, accurate and reliable analytical method for simultaneous determination of chlorite, chlorate, perchlorate and bromate in ozonated saline by using ion chromatography coupled with triple quadrupole mass spectrometry (IC-MS) has been developed.

Sign in / Sign up

Export Citation Format

Share Document