Simultaneous determination of benzoylmesaconine and piperine in rat plasma after oral administration of Naru-3 by an ultra fast liquid chromatography-tandem mass spectrometry method and its application in a comparative pharmacokinetic study

2014 ◽  
Vol 6 (10) ◽  
pp. 3420-3428 ◽  
Author(s):  
Yidi Yin ◽  
Jingjing Liu ◽  
Huarong Xu ◽  
Chunxiao Lv ◽  
Yiyang Du ◽  
...  

A rapid, sensitive and reliable UFLC-MS/MS method has been developed for the simultaneous quantitation of benzoylmesaconine and piperine in rat plasma after oral administration of Naru-3.

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