Mercuric-triggered hydrogen peroxide “turn-on” fluorescence detection in neuronal cells with novel fluorescein-based probe obtained in one pot

2013 ◽  
Vol 5 (11) ◽  
pp. 2650 ◽  
Author(s):  
Dhiraj P. Murale ◽  
Hyunjeong Liew ◽  
Yoo-Hun Suh ◽  
David G. Churchill
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescence Detection ◽  
Neuronal Cells ◽  
One Pot ◽  
Turn On

Preparation of a fluorescent silver nanoprism–dye complex for detection of hydrogen peroxide in milk

2015 ◽  
Vol 7 (23) ◽  
pp. 9749-9752 ◽  
Author(s):  
Chifang Peng ◽  
Chunli Liu ◽  
Zhengjun Xie
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescence Detection ◽  
Protein Complex ◽  
Detection Method ◽  
Fluorescent Dye ◽  
Silver Nanoprisms ◽  
Turn On

A simple and sensitive “turn-on” fluorescence detection method for H2O2in milk was developed based on H2O2induced morphology transitions of fluorescent dye–protein complex-capped silver nanoprisms (FDSNPs).

Neurotoxicity and Neuroprotective Effects of Polyimides (PI) and Polyphenylenevinylene (PPV) against Hydrogen Peroxide (H2O2)

2011 ◽  
Vol 8 (2) ◽  
pp. 33
Author(s):  
Norfaezah Mazalan ◽  
Mazatulikhma Mat Zain ◽  
Nor Saliyana Jumali ◽  
Norhanim Mohalid ◽  
Zurina Shaameri ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Drug Delivery Systems ◽  
Neuronal Cells ◽  
Water Soluble ◽  
Brain Delivery ◽  
Specific Therapy ◽  
Neuroprotective Effects ◽  
Water Soluble Polymer ◽  
Site Specific ◽  
Novel Drugs

Recently, research and development in the field of drug delivery systems (DDS) facilitating site-specific therapy has reached significant progression. DDS based on polymer micelles, coated micro- and nanoparticles, and various prodrug systems including water-soluble polymer have been prepared and extensively studied as novel drugs designed for cancer chemotherapy and brain delivery. Since polymers are going to be used in human, this study has the interest of testing two types of polymer, polyimides (PI) and polyphenylenevinylene (PPV) on neuronal cells. The objective of this study was to determine the possible neurotoxicity and potential neuroprotective effects of PI and PPV towards SH-SY5Y neuronal cells challenged by hydrogen peroxide (H2O2) as an oxidant. Cells were pretreated with either PI or PPV for 1 hour followed by incubation for 24 hour with 100 µM of H2O2. MTS assay was used to assess cell viability. Results show that PI and PPV are not harmful within the concentration up to 10 µM and 100 µM, respectively. However, PI and PPV do not protect neuronal cells against toxicity induced by H2O2 or further up the cell death.

scholarly journals Hydrogen Peroxide Toxicity Induces Ras Signaling in Human Neuroblastoma SH-SY5Y Cultured Cells

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Jirapa Chetsawang ◽  
Piyarat Govitrapong ◽  
Banthit Chetsawang
Keyword(s):  
Hydrogen Peroxide ◽  
Cell Viability ◽  
Cultured Cells ◽  
Neuronal Cells ◽  
Competitive Inhibitor ◽  
Ras Signaling ◽  
Ras Proteins ◽  
Human Neuroblastoma ◽  
Dependent Signaling Pathway

It has been reported that overproduction of reactive oxygen species occurs after brain injury and mediates neuronal cells degeneration. In the present study, we examined the role of Ras signaling on hydrogen peroxide-induced neuronal cells degeneration in dopaminergic neuroblastoma SH-SY5Y cells. Hydrogen peroxide significantly reduced cell viability in SH-SY5Y cultured cells. An inhibitor of the enzyme that catalyzes the farnesylation of Ras proteins, FTI-277, and a competitive inhibitor of GTP-binding proteins, GDP-beta-S significantly decreased hydrogen peroxide-induced reduction in cell viability in SH-SY5Y cultured cells. The results of this study might indicate that a Ras-dependent signaling pathway plays a role in hydrogen peroxide-induced toxicity in neuronal cells.

Fabrication of an “ion-imprinting” dual-emission quantum dot nanohybrid for selective fluorescence turn-on and ratiometric detection of cadmium ions

The Analyst ◽  
2016 ◽  
Vol 141 (20) ◽  
pp. 5886-5892 ◽  
Author(s):  
Jing Wang ◽  
Chenxing Jiang ◽  
Xiaoqi Wang ◽  
Ligeng Wang ◽  
Aimin Chen ◽  
...  
Keyword(s):  
Quantum Dot ◽  
Fluorescence Detection ◽  
Ratiometric Fluorescence ◽  
Dual Emission ◽  
Cadmium Ions ◽  
Turn On ◽  
Ratiometric Detection ◽  
Ion Imprinting ◽  
Fluorescence Turn On

A new CdTe@SiO2@CdSe nanohybrid was demonstrated for the ratiometric fluorescence detection of Cd2+via the turn-on model and “ion-imprinting” technique.

CuS/RGO hybrid by one-pot hydrothermal method for efficient electrochemical sensing of hydrogen peroxide

2017 ◽  
Vol 28 (6) ◽  
pp. 1306-1311 ◽  
Author(s):  
Wei Liu ◽  
Chaojun Lei ◽  
Hongxiu Zhang ◽  
Xiaolin Wu ◽  
Qing Jia ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Hydrothermal Method ◽  
Electrochemical Sensing ◽  
One Pot

Rosmarinic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced apoptosis

Toxicology ◽  
2008 ◽  
Vol 250 (2-3) ◽  
pp. 109-115 ◽  
Author(s):  
Hyo Jung Lee ◽  
Hong-Suk Cho ◽  
Euteum Park ◽  
Seung Kim ◽  
Sook-Young Lee ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Rosmarinic Acid ◽  
Neuronal Cells ◽  
Induced Apoptosis
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