Label-free selective detection of coralyne due to aptamer–coralyne interaction using DNA modified SiO2@Au core–shell nanoparticles as an effective SERS substrate

2013 ◽  
Vol 5 (16) ◽  
pp. 3927 ◽  
Author(s):  
Yilin Lu ◽  
Qing Huang
2018 ◽  
Vol 54 (95) ◽  
pp. 13399-13402 ◽  
Author(s):  
Qian Lv ◽  
Meng-Yue Gao ◽  
Zi-He Cheng ◽  
Qiao Chen ◽  
Ai-Guo Shen ◽  
...  

The unique “tip spots” can simultaneously enhance SERS and the photothermal effect, facilitating label-free SERS intracellular imaging during cell apoptosis.


NANO ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. 1750131 ◽  
Author(s):  
Jian Chen ◽  
Peitao Dong ◽  
Chaoguang Wang ◽  
Chenyu Zhang ◽  
Junfeng Wang ◽  
...  

A simple method for improving surface-enhanced Raman scattering (SERS) performance of aligned silver nanorod (Ag NR) array was investigated. This method was to construct a kind of hybrid substrate by grafting Au@Ag core–shell nanoparticles (NPs) into Ag NR array using poly(2-vinylphridine) (P2VPy) as a bridging agent. The hybrid substrate yielded excellent SERS performance as its detection limit improved from 10[Formula: see text] M to 10[Formula: see text] M using trans-1,2-bis(4-pyridyl)ethylene (BPE) as probe molecule, which was increased by two orders of magnitude compared with Ag NR array substrate. The significant improvement of SERS performance of Ag NR arrays was attributed to the addition of Au@Ag core–shell NPs. As a result of surface plasmon resonance generated by the interaction of electromagnetic (EM) (IAEM) filed between NP and NR structures, increasing hotspots were found at the connections of NPs and NRs, the gaps of adjacent rods, and the gaps of two particles consequently. These results were validated by the finite difference time domain (FDTD) calculation. Besides, hybrid substrate shows good performance in stability and reproducibility. The proposed method was simple and robust, which promoted SERS performance of Ag NR array effectively, showing great potential in the application of SERS substrate fabrication and SERS-based bio-chemical sensing.


Optik ◽  
2020 ◽  
Vol 221 ◽  
pp. 165274
Author(s):  
Ciyong Gu ◽  
Shi-Qing Man ◽  
Junqi Tang ◽  
Zhimin Zhao ◽  
Zhenlu Liu ◽  
...  

2015 ◽  
Vol 17 (33) ◽  
pp. 21149-21157 ◽  
Author(s):  
Yilin Lu ◽  
Guohua Yao ◽  
Kexi Sun ◽  
Qing Huang

A new type of surface-enhanced Raman scattering (SERS) substrate consisting of β-cyclodextrin (β-CD) coated SiO2@Au@Ag nanoparticles (SiO2@Au@Ag@CD NPs) has been achieved.


2017 ◽  
Vol 47 (9) ◽  
pp. 1283-1289
Author(s):  
Huiyun Wu ◽  
Xin Li ◽  
Jiawen Xu ◽  
Congwen Wang ◽  
Zhen Rong ◽  
...  

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