Electrochemical detection of leukemia oncogenes using enzyme-loaded carbon nanotube labels

The Analyst ◽  
2014 ◽  
Vol 139 (17) ◽  
pp. 4223-4230 ◽  
Author(s):  
Ai-Cheng Lee ◽  
Dan Du ◽  
Baowei Chen ◽  
Chew-Kiat Heng ◽  
Tit-Meng Lim ◽  
...  

An ultrasensitive electrochemical nucleic acid assay amplified by carbon nanotubes (CNTs)-based labels for the detection of leukemia oncogenes.

RSC Advances ◽  
2016 ◽  
Vol 6 (63) ◽  
pp. 58771-58779 ◽  
Author(s):  
Xiaoyue Yue ◽  
Pengxian Han ◽  
Wenxin Zhu ◽  
Jianlong Wang ◽  
Lixue Zhang

Facile and sensitive methyl parathion detection was achieved based on a novel carbon nanotube/carbon paper sensor.


2021 ◽  
Author(s):  
Gaurang Khot ◽  
Mohsin Kaboli ◽  
Tansu Celikel ◽  
Neil Shirtcliffe

Adrenaline and hydrogen peroxide have neuromodulatory functions in the brain.Considerable interest exists in developing electrochemical sensors that can detect their levels in vivo due to their important biochemical roles. Challenges associated with electrochemical detection of hydrogen peroxide and adrenaline are that the oxidation of these molecules usually requires highly oxidising potentials (beyond 1.4V vs Ag/AgCl) where electrode damage and biofouling are likely and the signals of adrenaline, hydrogen peroxide and adenosine overlap. To address these issues we fabricated pyrolysed carbon electrodes coated with oxidised carbon nanotubes (CNTs). Using these electrodes for fast-scan cyclic voltammetric (FSCV) measurements showed that the electrode offers reduced overpotentials compared with graphite and improved resistance to biofouling. The Adrenaline peak is reached at 0.75 V and reduced back at -0.2 V while hydrogen peroxide is detected at 0.85V on this electrode. The electrodes are highly sensitive with a sensitivity of16nA microM-1 for Adrenaline and 11nA microM-1 for hydrogen peroxide on an 80 micro m2 electrode. They are also suitable to distinguish between adrenaline, hydrogen peroxide and adenosine thus these probes can be used for multimodal detection of analytes.


2021 ◽  
Author(s):  
Kothandaraman Ramanujam ◽  
Tamilselvi Gurusamy ◽  
Rajendran Rajaram ◽  
Raja Murugan

The present work focuses on the electrochemical determination of hydrogen peroxide (H2O2), using a poly(bisbenzimidazolatocopper(II)) coordinated multiwalled carbon nanotube modified glassy carbon electrode (MWCNT/(BIM-Cu2+)n@GCE). The physical characterization techniques point to...


2003 ◽  
Vol 772 ◽  
Author(s):  
Masakazu Muroyama ◽  
Kazuto Kimura ◽  
Takao Yagi ◽  
Ichiro Saito

AbstractA carbon nanotube triode using Helicon Plasma-enhanced CVD with electroplated NiCo catalyst has been successfully fabricated. Isolated NiCo based metal catalyst was deposited at the bottom of the cathode wells by electroplating methods to control the density of carbon nanotubes and also reduce the activation energy of its growth. Helicon Plasma-enhanced CVD (HPECVD) has been used to deposit nanotubes at 400°C. Vertically aligned carbon nanotubes were then grown selectively on the electroplated Ni catalyst. Field emission measurements were performed with a triode structure. At a cathode to anode gap of 1.1mm, the turn on voltage for the gate was 170V.


2021 ◽  
Author(s):  
Manasi Doshi ◽  
Eric Paul Fahrenthold

Explosives and hazardous gas sensing using carbon nanotube (CNT) based sensors has been a focus of considerable experimental research. The simplest sensors have employed a chemiresistive sensing mechanism, and rely...


Author(s):  
Mohammad Hamza Kirmani ◽  
Geeta Sachdeva ◽  
Ravindra Pandey ◽  
Gregory M. Odegard ◽  
Richard Liang ◽  
...  

2007 ◽  
Vol 124-126 ◽  
pp. 1309-1312
Author(s):  
Nguyen Duc Hoa ◽  
Nguyen Van Quy ◽  
Gyu Seok Choi ◽  
You Suk Cho ◽  
Se Young Jeong ◽  
...  

A new type of gas sensor was realized by directly depositing carbon nanotube on nano channels of the anodic alumina oxide (AAO) fabricated on p-type silicon substrate. The carbon nanotubes were synthesized by thermal chemical vapor deposition at a very high temperature of 1200 oC to improve the crystallinity. The device fabrication process was also developed. The contact of carbon nanotubes and p-type Si substrate showed a Schottky behavior, and the Schottky barrier height increased with exposure to gases while the overall conductivity decreased. The sensors showed fast response and recovery to ammonia gas upon the filling (400 mTorr) and evacuation.


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