nido-[{(C5Me5)Ir}B3H7{(PPh3)2(CO)Os}], closo-[{(C5Me5)Ir}B4H6{(PPh3)2(CO)Os}] and pileo-[{(PPh3)COHIr}B5H5{(PPh3)2(CO)Os}]: a unique homologous series of iridaosmaborane cluster types

1995 ◽  
pp. 1285 ◽  
Author(s):  
Jonathan Bould ◽  
Nigam P. Rath ◽  
Lawrence Barton
Keyword(s):  
Homologous Series

NOVEL SMECTIC POLYMORPHIC BEHAVIOUR IN HOMOLOGOUS SERIES OF MESOGENS

1975 ◽  
Vol 36 (C1) ◽  
pp. C1-365-C1-374 ◽  
Author(s):  
D. COATES ◽  
G. W. GRAY
Keyword(s):  
Homologous Series

Homologation: A Versatile Molecular Modification Strategy to Drug Discovery

2019 ◽  
Vol 19 (19) ◽  
pp. 1734-1750 ◽  
Author(s):  
Lídia M. Lima ◽  
Marina A. Alves ◽  
Daniel N. do Amaral
Keyword(s):  
Protein Structure ◽  
Homologous Series ◽  
Molecular Conformation ◽  
Chemical Properties ◽  
Lead Optimization ◽  
Pharmacokinetic Property ◽  
Molecular Modification ◽  
Physico Chemical ◽  
Pharmacokinetic Properties ◽  
Lead Identification

Homologation is a concept introduced by Gerhard in 1853 to describe a homologous series in organic chemistry. Since then, the concept has been adapted and used in medicinal chemistry as one of the most important strategies for molecular modification. The homologation types, their influence on physico-chemical properties and molecular conformation are presented and discussed. Its application in lead-identification and lead optimization steps, as well as its impact on pharmacodynamics/pharmacokinetic properties and on protein structure is highlighted from selected examples. <p> • Homologation: definition and types <p> • Homologous series in nature <p> • Comparative physico-chemical and conformational properties <p> • Application in lead-identification and lead-optimization <p> • Impact on pharmacodynamic property <p> • Impact on pharmacokinetic property <p> • Impact on protein structure <p> • Concluding remarks <p> • Acknowledgment <p> • References

The effect of steric size of leaving group on rates of the competing syn- and anti-pathways in biomolecular elimination

1980 ◽  
Vol 45 (8) ◽  
pp. 2171-2178
Author(s):  
Jiří Závada ◽  
Magdalena Pánková
Keyword(s):  
Comparative Analysis ◽  
Homologous Series ◽  
Leaving Group ◽  
Leaving Groups

Approximate rates of the competing syn- and anti-pathways have been determined in t-C4H9OK-t-C4H9OH promoted elimination from two homologous series of tosylates: I-OTs trans-III (R = H, CH3, C2H5, n-C3H7, i-C3H7, t-C4H9) and II-OTs trans-IV (R = CH3, C2H5, n-C3H7, i-C3H7, t-C4H9). A comparison has been made with rates of the same processes in the (+) elimination of the corresponding trimethylammonium salts I-N(CH3)3 trans-III and (+) II-N(CH3)3 trans-IV. The title effect is demonstrated by a comparative analysis of the rate patterns obtained for the two leaving groups.

Pavonite homologues as potential n-type thermoelectric materials: crystal structure and performance

2021 ◽  
Author(s):  
Shangqing Qu ◽  
Jing Zhao ◽  
Zimin Jiang ◽  
Dequan Jiang ◽  
Yonggang Wang
Keyword(s):  
Crystal Structure ◽  
Thermoelectric Material ◽  
Thermoelectric Materials ◽  
Homologous Series ◽  
And Performance

The pavonite homologous series assembled from two basic modules is a potential n-type thermoelectric material.

Surface Energies of Nonionic Surfactants Adsorbed onto Nylon Fiber and a Correlation with Their Solubility Parameters

1992 ◽  
Vol 62 (9) ◽  
pp. 535-546 ◽  
Author(s):  
Philip E. Slade ◽  
Debra N. Hild
Keyword(s):  
Homologous Series ◽  
Nonionic Surfactants ◽  
Solubility Parameters ◽  
Nylon 66 ◽  
Synthetic Fibers ◽  
Surface Energies ◽  
Nylon Fiber

The surface energies of spin finishes adsorbed onto synthetic fibers are a major factor in determining the processing capabilities of these fibers. They also play a key role in determining how wettable the fibers are by other materials that may be applied to yarn or fabrics in later stages of processing, such as dyes, sizes, or anti-soiling agents. We have applied several homologous series of nonionic surfactants, which can be used as spin finish emulsifiers, to nylon 66 fibers and determined the polar, dispersion, and total surface energies of these adsorbed materials. We also propose a relationship between the measured surface energies and the calculated Hansen fractional solubility parameters.

scholarly journals Molecular association of normal alkanoic acids with their thallium(I) salts: a new homologous series of fatty acid metal soaps

1997 ◽  
Vol 38 (2) ◽  
pp. 361-372
Author(s):  
M Fernández-García ◽  
M V García ◽  
M I Redondo ◽  
J A Cheda ◽  
M Fernández-García ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Homologous Series ◽  
Molecular Association ◽  
Alkanoic Acids ◽  
Metal Soaps
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