Electrospray mass spectrometry of the self-assembly of a capped polymetallic complex

1993 ◽  
pp. 990-993 ◽  
Author(s):  
Emmanuelie Leize ◽  
Alain Van Dorsselaer ◽  
Roland Krämer ◽  
Jean-Marie Lehn
Keyword(s):  
Mass Spectrometry ◽  
Self Assembly ◽  
Electrospray Mass Spectrometry ◽  
The Self

Investigation of the Self-Assembly Pathway of Pentanuclear Helicates by Electrospray Mass Spectrometry

1996 ◽  
Vol 2 (11) ◽  
pp. 1395-1398 ◽  
Author(s):  
Annie Marquis-Rigault ◽  
Annick Dupont-Gervais ◽  
Alain Van Dorsselaer ◽  
Jean-Marie Lehn
Keyword(s):  
Mass Spectrometry ◽  
Self Assembly ◽  
Electrospray Mass Spectrometry ◽  
The Self ◽  
Assembly Pathway

Self-Assembly of an 11-Component Cylindrical Inorganic Architecture:  Electrospray Mass Spectrometry and Thermodynamic Studies

1996 ◽  
Vol 35 (8) ◽  
pp. 2307-2310 ◽  
Author(s):  
Annie Marquis-Rigault ◽  
Annick Dupont-Gervais ◽  
Paul N. W. Baxter ◽  
Alain Van Dorsselaer ◽  
Jean-Marie Lehn
Keyword(s):  
Mass Spectrometry ◽  
Self Assembly ◽  
Electrospray Mass Spectrometry ◽  
Thermodynamic Studies

scholarly journals Self-assembly of metallosupramolecular rhombi from chiral concave 9,9’-spirobifluorene-derived bis(pyridine) ligands

2014 ◽  
Vol 10 ◽  
pp. 432-441 ◽  
Author(s):  
Rainer Hovorka ◽  
Sophie Hytteballe ◽  
Torsten Piehler ◽  
Georg Meyer-Eppler ◽  
Filip Topić ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Single Crystal ◽  
Self Assembly ◽  
The Self ◽  
Assembly Process ◽  
X Ray Diffraction ◽  
X Ray ◽  
Pyridine Ligands ◽  
Racemic Form

Two new 9,9’-spirobifluorene-based bis(4-pyridines) were synthesised in enantiopure and one also in racemic form. These ligands act as concave templates and form metallosupramolecular [(dppp)2M2L2] rhombi with cis-protected [(dppp)Pd]2+ and [(dppp)Pt]2+ ions. The self-assembly process of the racemic ligand preferably occurs in a narcissistic self-recognising manner. Hence, a mixture of all three possible stereoisomers [(dppp)2M2{(R)-L}2](OTf)4, [(dppp)2M2{(S)-L}2](OTf)4, and [(dppp)2M2{(R)-L}{(S)-L}](OTf)4 was obtained in an approximate 1.5:1.5:1 ratio which corresponds to an amplification of the homochiral assemblies by a factor of approximately three as evidenced by NMR spectroscopy and mass spectrometry. The racemic homochiral assemblies could also be characterised by single crystal X-ray diffraction.

scholarly journals hu.MAP 2.0: Integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies

2020 ◽  
Author(s):  
Kevin Drew ◽  
John B. Wallingford ◽  
Edward M. Marcotte
Keyword(s):  
Machine Learning ◽  
Mass Spectrometry ◽  
Structural Biology ◽  
Self Assembly ◽  
Protein Complexes ◽  
The Self ◽  
Web Interface ◽  
Valuable Resource ◽  
Cellular Functions ◽  
Learning Framework

AbstractA general principle of biology is the self-assembly of proteins into functional complexes. Characterizing their composition is, therefore, required for our understanding of cellular functions. Unfortunately, we lack a comprehensive set of protein complexes for human cells. To address this gap, we developed a machine learning framework to identify protein complexes in over 15,000 mass spectrometry experiments which resulted in the identification of nearly 7,000 physical assemblies. We show our resource, hu.MAP 2.0, is more accurate and comprehensive than previous resources and gives rise to many new hypotheses, including for 274 completely uncharacterized proteins. Further, we identify 259 promiscuous proteins that participate in multiple complexes pointing to possible moonlighting roles. We have made hu.MAP 2.0 easily searchable in a web interface (http://humap2.proteincomplexes.org/), which will be a valuable resource for researchers across a broad range of interests including systems biology, structural biology, and molecular explanations of disease.

scholarly journals Metallo-organic ensembles of tritopic subphthalocyanine ligands

2017 ◽  
Vol 21 (12) ◽  
pp. 782-789 ◽  
Author(s):  
M. Ángel Revuelta-Maza ◽  
Ettore Fazio ◽  
Gema de la Torre ◽  
Tomás Torres
Keyword(s):  
Mass Spectrometry ◽  
Self Assembly ◽  
Direct Injection ◽  
Building Blocks ◽  
The Self ◽  
Assembly Process ◽  
Text Structures ◽  
Assembly Method ◽  
Injection Techniques

Organic building blocks containing amines and aldehydes can be used for the preparation of complex metallo-organic structures, such as M[Formula: see text]L[Formula: see text] triple helicates or face-capped M[Formula: see text]L[Formula: see text] tetrahedral cages, through the formation of both dynamic covalent and coordinative linkages during the self-assembly process. Herein we describe how the subcomponent self-assembly method can be succesfully applied over a triamine-functionalized subphthalocyanine (SubPc) ligand to build metallo-supramolecular helicates. Two isomeric SubPcs (C[Formula: see text]-SubPc1 and C[Formula: see text]-SubPc1) have been prepared from the corresponding C[Formula: see text]-SubPcI[Formula: see text] and C[Formula: see text]-SubPcI[Formula: see text] precursors under optimized Suzuki conditions. We selected the tritopic C[Formula: see text]-SubPc1 derivative as ligand for the subcomponent self-assembly experiments, which involved the reaction with 2-formylpyridine and different Fe(II) salts. The self-assembly process was mainly studied by mass spectrometry (ESI direct injection techniques), and in all the conditions applied, we could observe the formation of helicate-type Fe[Formula: see text]SubPc[Formula: see text] structures and/or Fe[Formula: see text]SubPc[Formula: see text] species, which can be considered as open precursors of Fe[Formula: see text]SubPc[Formula: see text] tetrahedral cages.

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