A simple synthesis of the ripening agent 1-aminocyclopropane-1-carboxylic acid

Author(s):  
Patricia M. Angus ◽  
Bernard T. Golding ◽  
Alan M. Sargeson
2008 ◽  
Vol 63 (2) ◽  
pp. 210-216 ◽  
Author(s):  
Seikwan Oh ◽  
Jae-Chul Jung ◽  
Mitchell A. Avery

A convenient synthesis of 4-substituted 2-(3-hydroxy-2-oxo-1-phenethylpropylcarbamoyl)pyrrolidine- 1-carboxylic acid benzyl esters 17 and 18 as new cysteine protease inhibitors is described. The synthetic key strategies involve the diazocarbonyl insertion reaction of N-Boc-L-homophenylalanine (1) by diazomethane, acetylation of the bromoketone 2 with sodium acetate, and condensation of acids 12, 14 with (3S)-3-amino-2-oxo-5-phenyl-pentyl acetate monohydrochloride (4) in good yield


2019 ◽  
Vol 60 (39) ◽  
pp. 151084
Author(s):  
Debasis Sahoo ◽  
Sohini Sarkar ◽  
Samaresh Jana

2016 ◽  
Vol 217 (15) ◽  
pp. 1745-1751 ◽  
Author(s):  
Javier F. Guastavino ◽  
Victoria A. Vaillard ◽  
Mariano D. Cristaldi ◽  
Lorena Rossini ◽  
Santiago E. Vaillard

ChemInform ◽  
2010 ◽  
Vol 24 (36) ◽  
pp. no-no
Author(s):  
P. M. ANGUS ◽  
B. T. GOLDING ◽  
A. M. SARGESON

1990 ◽  
Vol 54 (7) ◽  
pp. 1845-1846 ◽  
Author(s):  
Mitsunori Kirihata ◽  
Akio Sakamoto ◽  
Itsuo Ichimoto ◽  
Hiroo Ueda ◽  
Mamoru Honma

ChemInform ◽  
2010 ◽  
Vol 23 (12) ◽  
pp. no-no
Author(s):  
L. I. ZAKHARKIN ◽  
V. V. GUSEVA

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