The mechanism of methyl radical loss from CH3CHCHCH(CH3)OCH3+˙and CH2C(CH3)CH(CH3)OCH3+˙: a not-so-simple cleavage

1991 ◽  
pp. 1055-1057 ◽  
Author(s):  
Richard D. Bowen ◽  
Andrew D. Wright
Keyword(s):  
Methyl Radical ◽  
Methyl Radical Loss

Formation threshold structures of some [C5H7O]+ ions: use of general schemes for estimation of heats of formation of gas-phase organic ions

1985 ◽  
Vol 63 (4) ◽  
pp. 833-835 ◽  
Author(s):  
Mehrshid Alai ◽  
Giorgio G. Attardo ◽  
Robin T. B. Rye
Keyword(s):  
Gas Phase ◽  
Heat Of Formation ◽  
Molecular Ions ◽  
Thermochemical Data ◽  
Mesityl Oxide ◽  
Methyl Radical ◽  
Organic Ions ◽  
Gas Phase Ions ◽  
Structure Assignment ◽  
Methyl Radical Loss

Recently published correlations between heat of formation and structure of gas-phase ions have been used to assign formation threshold structures to [C5H7O]+ ions produced by methyl radical loss from molecular ions of mesityl oxide, 5-hexene-2-one, 3-methylcyclopentanone, and 2-cyclohexenol. An unambiguous structure assignment has been made for the [C5H7O]+ daughter ion from mesityl oxide. For the three other precursors two common formation-threshold structures consistent with the thermochemical data are proposed.

Losses of CO and CO2 upon collision-activated dissociation of substituted 2-methoxyphenoxides after methyl radical loss

2020 ◽  
Vol 456 ◽  
pp. 116397
Author(s):  
Christopher L. Marcum ◽  
James S. Riedeman ◽  
Tiffany M. Jarrell ◽  
John J. Nash ◽  
Hilkka I. Kenttämaa
Keyword(s):  
Methyl Radical ◽  
Methyl Radical Loss

Kinetics of the Reactions of Methyl Radical with Hydrogen, Methyl and Ethyl Peroxides

2021 ◽  
Vol 6 (7) ◽  
pp. 1548-1554
Author(s):  
Fei Cao ◽  
Gai Shi ◽  
Jinou Song ◽  
Pengzhen Tian ◽  
Zhijun Li
Keyword(s):  
Methyl Radical ◽  
Kinetics Of

scholarly journals Correlation of methylation status in MTHFR promoter region with recurrent pregnancy loss

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Mai Mahmoud Shaker ◽  
Taghreed Abdelmoniem shalabi ◽  
Khalda said Amr
Keyword(s):  
Dna Methylation ◽  
Dna Sequences ◽  
Promoter Region ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Methylation Status ◽  
Control Group ◽  
Case Group ◽  
Methyl Radical ◽  
Fertile Women

Abstract Background DNA methylation is an epigenetic process for modifying transcription factors in various genes. Methylenetetrahydrofolate reductase (MTHFR) stimulates synthesis of methyl radical in the homocysteine cycle and delivers methyl groups needed in DNA methylation. Furthermore, numerous studies have linked gene polymorphisms of this enzyme with a larger risk of recurrent pregnancy loss (RPL), yet scarce information is available concerning the association between epigenetic deviations in this gene and RPL. Hypermethylation at precise DNA sequences can function as biomarkers for a diversity of diseases. We aimed by this study to evaluate the methylation status of the promoter region of MTHFR gene in women with RPL compared to healthy fertile women. It is a case–control study. Hundred RPL patients and hundred healthy fertile women with no history of RPL as controls were recruited. MTHFR C677T was assessed by polymerase chain reaction-restriction fragment length polymorphism (RFLP). Quantitative evaluation of DNA methylation was performed by high-resolution melt analysis by real-time PCR. Results The median of percentage of MTHFR promoter methylation in RPL cases was 6.45 [0.74–100] vs. controls was 4.50 [0.60–91.7], P value < 0.001. In the case group, 57 hypermethylated and 43 normo-methylated among RPL patients vs. 40 hypermethylated and 60 normo-methylated among controls, P< 0.005. Frequency of T allele in C677T MTHFR gene among RPL patients was 29% vs. 23% among the control group; C allele vs. T allele: odds ratio (OR) = 1.367 (95% confidence interval (CI) 0.725–2.581). Conclusion Findings suggested a significant association between hypermethylation of the MTHFR promoter region in RPL patients compared to healthy fertile women.

ChemInform Abstract: DIFFERENCE FREQUENCY LASER SPECTROSCOPY OF THE ν3 BAND OF THE METHYL RADICAL

1983 ◽  
Vol 14 (8) ◽  
Author(s):  
T. AMANO ◽  
P. F. BERNATH ◽  
C. YAMADA ◽  
Y. ENDO ◽  
E. HIROTA
Keyword(s):  
Laser Spectroscopy ◽  
Difference Frequency ◽  
Methyl Radical ◽  
Frequency Laser
Sign in / Sign up

Export Citation Format

Share Document