A facile chemoenzymatic route to optically pure building blocks for cyclopentanoid natural products

1986 ◽  
pp. 1298 ◽  
Author(s):  
Kurt Laumen ◽  
Manfred P. Schneider
Keyword(s):  
Natural Products ◽  
Building Blocks ◽  
Optically Pure

Formation of Carbon-Oxygen Bond Mediated by Hypervalent Iodine Reagents Under Metal-free Conditions

2020 ◽  
Vol 17 ◽  
Author(s):  
Ayesha Jalil ◽  
Yaxin O Yang ◽  
Zhendong Chen ◽  
Rongxuan Jia ◽  
Tianhao Bi ◽  
...  
Keyword(s):  
Natural Products ◽  
Bond Formation ◽  
Building Blocks ◽  
Review Article ◽  
Hypervalent Iodine ◽  
Metal Free ◽  
Bioactive Natural Products ◽  
The Past ◽  
Oxygen Bond ◽  
Privileged Scaffolds

: Hypervalent iodine reagents are a class of non-metallic oxidants have been widely used in the construction of several sorts of bond formations. This surging interest in hypervalent iodine reagents is essentially due to their very useful oxidizing properties, combined with their benign environmental character and commercial availability from the past few decades ago. Furthermore, these hypervalent iodine reagents have been used in the construction of many significant building blocks and privileged scaffolds of bioactive natural products. The purpose of writing this review article is to explore all the transformations in which carbon-oxygen bond formation occurred by using hypervalent iodine reagents under metal-free conditions

scholarly journals Non-Enzymatic Desymmetrization Reactions in Aqueous Media

Symmetry ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 720
Author(s):  
Satomi Niwayama
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Functional Groups ◽  
Organic Compounds ◽  
Recent Progress ◽  
Aqueous Media ◽  
Building Blocks ◽  
Organic Reactions ◽  
Environmentally Benign ◽  
Enzymatic Desymmetrization

Symmetric organic compounds are generally obtained inexpensively, and therefore they can be attractive building blocks for the total synthesis of various pharmaceuticals and natural products. The drawback is that discriminating the identical functional groups in the symmetric compounds is difficult. Water is the most environmentally benign and inexpensive solvent. However, successful organic reactions in water are rather limited due to the hydrophobicity of organic compounds in general. Therefore, desymmetrization reactions in aqueous media are expected to offer versatile strategies for the synthesis of a variety of significant organic compounds. This review focuses on the recent progress of desymmetrization reactions of symmetric organic compounds in aqueous media without utilizing enzymes.

Synthesis of Optically Pure 2-Aziridinemethanols: Versatile Synthetic Building Blocks.

1994 ◽  
Vol 42 (11) ◽  
pp. 2241-2250 ◽  
Author(s):  
Nobutaka FUJII ◽  
Kazuo NAKAI ◽  
Hiromu HABASHITA ◽  
Yuka HOTTA ◽  
Hirokazu TAMAMURA ◽  
...  
Keyword(s):  
Building Blocks ◽  
Optically Pure

New Versatile Fluorinated Chiral Building Blocks:  Synthesis and Reactivity of Optically Pure α-(Fluoroalkyl)-β-sulfinylenamines

1996 ◽  
Vol 61 (10) ◽  
pp. 3375-3387 ◽  
Author(s):  
Alberto Arnone ◽  
Pierfrancesco Bravo ◽  
Silvia Capelli ◽  
Giovanni Fronza ◽  
Stefano V. Meille ◽  
...  
Keyword(s):  
Building Blocks ◽  
Optically Pure

6-Siloxy-Substituted 5,6-Dihydro-4H-1,2-oxazines as Key Building Blocks for Natural Products

1992 ◽  
Vol 1992 (7) ◽  
pp. 709-714 ◽  
Author(s):  
Reinhold Zimmer ◽  
Markus Collas ◽  
Michael Roth ◽  
Hans-Ulrich Reißig
Keyword(s):  
Natural Products ◽  
Building Blocks
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