A new class of hydride-bridged platinum complex with application as hydrosilylation catalysts; molecular and X-ray crystal structure of trans-di-µ-hydrido-bis(tricyclohexylphosphine)bis(triethylsilyl)diplatinum(Pt–Pt)

1976 ◽  
pp. 671-672 ◽  
Author(s):  
Michael Green ◽  
Judith A. K. Howard ◽  
Jill Proud ◽  
John L. Spencer ◽  
F. Gordon A. Stone ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Platinum Complex ◽  
X Ray ◽  
New Class

Synthesis and Structure of a New Class of Fused Heterocycle with 8,9-Dihydro-pyridazino[1,2,4]triazine Skeleton

2017 ◽  
Vol 68 (6) ◽  
pp. 1159-1162
Author(s):  
Ionel Humelnicu ◽  
Violeta Vasilache
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bond ◽  
Spectral Analysis ◽  
Heterocyclic System ◽  
Intensity Data ◽  
Methyl Group ◽  
X Ray ◽  
New Class ◽  
Out Of Plane

The synthesis and X-ray crystal structure of a new class of fused heterocycle with 8,9-dihydro-pyridazino[1,2,4]triazine type 2 is reported. The synthesis is facile and efficient and, the structure of compounds was proven by elemental and spectral analysis, the X-ray spectra including (for 2b). The compound crystallizes in the space group P21/N (monoclinic) with a = 9.0077(2) �, b = 10.20019(18) �, c = 14.0099(3) �, a= 90�, b = 89.768(2)�, g= 90�, V= 1287.22(5) and Z = 4. Accurate molecular parameters for the heterocyclic system were obtained from intensity data collected at 200(14) K. The molecule 8,9-dihydro-pyridazino[1,2,4]triazine type 2 is a noncoplanar bicyclic fused system, with an envelope shape onto the triazine moiety, the C12 carbon being out of plane. The methyl group from the C12 carbon it is almost perpendicular on the triazine plane. We also notice a rather powerful hydrogen bond between hydrogen atom from N1 and the oxygen from the C11=O1 carbonyl group.

A PASE Approach to the Synthesis of Benzimidazopurines as Polycondensed Purine Derivatives

Synthesis ◽  
2020 ◽  
Vol 52 (23) ◽  
pp. 3622-3631
Author(s):  
Victor V. Fedotov ◽  
Evgeny N. Ulomsky ◽  
Konstantin V. Savateev ◽  
Evgeny M. Mukhin ◽  
Denis A. Gazizov ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Structure Analysis ◽  
Medicinal Chemistry ◽  
Crystal Structure Analysis ◽  
Purine Derivatives ◽  
Acidic Media ◽  
X Ray ◽  
New Class ◽  
Highly Efficient ◽  
Derivatives Of

A highly efficient PASE approach to a new class of polycyclic purine derivatives has been proposed. The strategy includes a consecutive reduction, auto-aromatization, and heterocyclization of the initial nitrobenzimidazopyrimidines obtained by a three-component condensation. It was shown that reduction of nitrobenzimidazopyrimidines by metals in acidic media was more efficient than heterogeneous hydro­genation. Novel derivatives of benz[4,5]imidazo[1,2-a]purines were obtained­ in good yields and the proposed structure was confirmed by X-ray crystal structure analysis. The obtained convergent benzimidazopurines combine two relevant medicinal chemistry scaffolds – benz­imidazole and purine.

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