Improved pH-responsive amphiphilic carboxymethyl-hexanoyl chitosan–poly(acrylic acid) macromolecules for biomedical applications

Soft Matter ◽  
2013 ◽  
Vol 9 (8) ◽  
pp. 2458 ◽  
Author(s):  
Meng-Hsuan Hsiao ◽  
Kuan-Hui Lin ◽  
Dean-Mo Liu
Keyword(s):  
Acrylic Acid ◽  
Biomedical Applications ◽  
Ph Responsive ◽  
Hexanoyl Chitosan ◽  
Poly Acrylic Acid

Dendritic magnetite decorated by pH-responsive PEGylated starch: a smart multifunctional nanocarrier for the triggered release of anti-cancer drugs

RSC Advances ◽  
2015 ◽  
Vol 5 (60) ◽  
pp. 48586-48595 ◽  
Author(s):  
Ali Pourjavadi ◽  
Zahra Mazaheri Tehrani ◽  
Seyed Hassan Hosseini
Keyword(s):  
Acrylic Acid ◽  
Cancer Drugs ◽  
Ph Responsive ◽  
Triggered Release ◽  
Anti Cancer ◽  
Poly Acrylic Acid

In the present study, we designed a pH-responsive drug nanocarrier based on polyamidoamine-modified Fe3O4 nanoparticles coated by PEGylated starch-co-poly(acrylic acid).

Preparation of Poly(Acrylic Acid) Crosslinked-Gold Nanoparticles for Colorimetric Detection of Analytes

2019 ◽  
Vol 950 ◽  
pp. 138-143
Author(s):  
Erindyah Retno Wikantyasning ◽  
Mutmainnah Mutmainnah ◽  
Ghiyats Ramadhan ◽  
Zakky Cholisoh ◽  
Muhammad Da'i
Keyword(s):  
Gold Nanoparticles ◽  
Herbal Medicine ◽  
Acrylic Acid ◽  
Color Change ◽  
Colorimetric Detection ◽  
Ph Responsive ◽  
Herbal Medicine Product ◽  
Responsive Polymer ◽  
Medicine Product ◽  
Poly Acrylic Acid

The aims of this study are to synthesize and characterize gold nanoparticles (AuNPs) crosslinked by pH-responsive polymer poly (acrylic acid) (PAA) and its application for detection of some analytes in herbal medicine product. In this study, a pH-responsive polymer, poly (acrylic acid) was prepared by the reversible addition-fragmentation chain transfer (RAFT) polymerization method. The polymer was then cross-linked by gold nanoparticles, which was synthesized by the Turkevich method. The response of the AuNPs-crosslinked PAA was observed by the color change from red to blue at a specific pH (4-5) and was characterized by TEM. The reversible color change was resulted from aggregation and disaggregation of the AuNPs due to the shrinking and swelling of the polymer when different pH was introduced as a stimulant. This sensor has the capability of recognizing analytes such as aspirin and tolbutamide added in the herbal medicine product at the concentration of 0.04-0.05 M.

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