scholarly journals Protein adhesion regulated by the nanoscale surface conformation

Soft Matter ◽  
2012 ◽  
Vol 8 (47) ◽  
pp. 11801 ◽  
Author(s):  
Eun Chul Cho ◽  
Hyunjoon Kong ◽  
Tae Byeong Oh ◽  
Kilwon Cho
Keyword(s):  
Protein Adhesion ◽  
Surface Conformation

Mechanisms of Protein Adhesion on Surface Films of Hydrophobin

Langmuir ◽  
2010 ◽  
Vol 26 (11) ◽  
pp. 8491-8496 ◽  
Author(s):  
Zefang Wang ◽  
Michael Lienemann ◽  
Mingqiang Qiau ◽  
Markus B. Linder
Keyword(s):  
Surface Films ◽  
Protein Adhesion

scholarly journals Honeycomb structured porous interfaces as templates for protein adhesion

2010 ◽  
Vol 252 ◽  
pp. 012002
Author(s):  
J Rodríguez-Hernández ◽  
A Muñoz-Bonilla ◽  
E Ibarboure ◽  
V Bordegé ◽  
M Fernández-García
Keyword(s):  
Protein Adhesion

Diphenylhydantoin plays a role in gene expression related to cytoskeleton and protein adhesion in human normal palate fibroblasts

Pathology ◽  
2009 ◽  
Vol 41 (3) ◽  
pp. 261-268 ◽  
Author(s):  
Furio Pezzetti ◽  
Francesco Carinci ◽  
Annalisa Palmieri ◽  
Laura Vizzotto ◽  
Claudia Moscheni ◽  
...  
Keyword(s):  
Gene Expression ◽  
Protein Adhesion

scholarly journals Vitronectin is a critical protein adhesion substrate for IL‐4‐induced foreign body giant cell formation

2008 ◽  
Vol 86A (2) ◽  
pp. 535-543 ◽  
Author(s):  
Amy K. McNally ◽  
Jacqueline A. Jones ◽  
Sarah R. MacEwan ◽  
Erica Colton ◽  
James M. Anderson
Keyword(s):  
Foreign Body ◽  
Giant Cell ◽  
Cell Formation ◽  
Foreign Body Giant Cell ◽  
Giant Cell Formation ◽  
Protein Adhesion

scholarly journals Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers

RSC Advances ◽  
2020 ◽  
Vol 10 (37) ◽  
pp. 21907-21913 ◽  
Author(s):  
Martina Banchelli ◽  
Roberta Cascella ◽  
Cristiano D'Andrea ◽  
Leszek Cabaj ◽  
Iacopo Osticioli ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Structural Determinants ◽  
Surface Conformation

Unraveling characteristic structural determinants at the basis of Aβ42 oligomers' neurotoxicity by a sub-molecular SERS investigation of their surface.

scholarly journals Recent Developments in the Design of Non-Biofouling Coatings for Nanoparticles and Surfaces

2020 ◽  
Vol 21 (3) ◽  
pp. 1007 ◽  
Author(s):  
Carlos Sanchez-Cano ◽  
Mónica Carril
Keyword(s):  
Gold Standard ◽  
Protein Corona ◽  
The Other ◽  
Engineered Surfaces ◽  
Recent Developments ◽  
Protein Adhesion ◽  
And Performance ◽  
The One ◽  
Biological Context

Biofouling is a major issue in the field of nanomedicine and consists of the spontaneous and unwanted adsorption of biomolecules on engineered surfaces. In a biological context and referring to nanoparticles (NPs) acting as nanomedicines, the adsorption of biomolecules found in blood (mostly proteins) is known as protein corona. On the one hand, the protein corona, as it covers the NPs’ surface, can be considered the biological identity of engineered NPs, because the corona is what cells will “see” instead of the underlying NPs. As such, the protein corona will influence the fate, integrity, and performance of NPs in vivo. On the other hand, the physicochemical properties of the engineered NPs, such as their size, shape, charge, or hydrophobicity, will influence the identity of the proteins attracted to their surface. In this context, the design of coatings for NPs and surfaces that avoid biofouling is an active field of research. The gold standard in the field is the use of polyethylene glycol (PEG) molecules, although zwitterions have also proved to be efficient in preventing protein adhesion and fluorinated molecules are emerging as coatings with interesting properties. Hence, in this review, we will focus on recent examples of anti-biofouling coatings in three main areas, that is, PEGylated, zwitterionic, and fluorinated coatings.

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