In situ preparation of silver nanoparticles on biocompatible methacrylated poly(vinyl alcohol) and cellulose based polymeric nanofibers

RSC Advances ◽  
2012 ◽  
Vol 2 (30) ◽  
pp. 11389 ◽  
Author(s):  
Narahari Mahanta ◽  
Suresh Valiyaveettil
2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Xiaojuan Zhang ◽  
Wenbin Cai ◽  
Lingyun Hao ◽  
Wei Zhang

This study synthesized poly(vinyl alcohol)/carboxymethyl chitosan/cyanidin (PVA/CMCS/CY) hydrogel films. First, PVA and CMCS were used to synthesize hydrogel films by ultraviolet irradiation. Meanwhile, CY was in situ combined into the hydrogel films through the electrostatic attraction between CMCS and CY. Next, the products were analyzed using Fourier-transform infrared spectroscopy, scanning electron microscopy, contact angle test, swelling analysis, and mechanical property test. The results revealed that compared with PVA/CMCS hydrogel films, the PVA/CMCS/CY hydrogel films had an interporous structure and good swelling and mechanical properties. Moreover, the drug release experiments demonstrated that the PVA/CMCS/CY hydrogel films had a CY encapsulation efficiency of 33.5% with a sustained CY release of up to 60 h. Furthermore, the examined antibacterial activities against Staphylococcus aureus and Escherichia coli showed that the porous PVA/CMCS/CY hydrogel films exhibited a certain inhibition. Cell viability experiments demonstrated that the PVA/CMCS/CY films displayed no obvious cytotoxicity to human umbilical vein endothelial cells.


2014 ◽  
Vol 96 ◽  
pp. 158-166 ◽  
Author(s):  
Jelena Krstić ◽  
Jelena Spasojević ◽  
Aleksandra Radosavljević ◽  
Milorad Šiljegovć ◽  
Zorica Kačarević-Popović

2018 ◽  
Vol 40 (4) ◽  
pp. 1322-1328 ◽  
Author(s):  
Atena Golabdar ◽  
Hossein Adelnia ◽  
Nooshafarin Moshtzan ◽  
Jaber Nasrollah Gavgani ◽  
Hossein Izadi‐Vasafi

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 96
Author(s):  
John Jackson ◽  
Helen Burt ◽  
Dirk Lange ◽  
In Whang ◽  
Robin Evans ◽  
...  

The prompt treatment of burn wounds is essential but can be challenging in remote parts of Africa, where burns from open fires are a constant hazard for children and suitable medical care may be far away. Consequently, there is an unmet need for an economical burn wound dressing with a sustained antimicrobial activity that might be manufactured locally at low cost. This study describes and characterizes the novel preparation of a silver nitrate-loaded/poly(vinyl alcohol) (PVA) film. Using controlled heating cycles, films may be crosslinked with in situ silver nanoparticle production using only a low heat oven and little technical expertise. Our research demonstrated that heat-curing of PVA/silver nitrate films converted the silver to nanoparticles. These films swelled in water to form a robust, wound-compatible hydrogel which exhibited controlled release of the antibacterial silver nanoparticles. An optimal formulation was obtained using 5% (w/w) silver nitrate in PVA membrane films that had been heated at 140 °C for 90 min. Physical and chemical characterization of such films was complemented by in vitro studies that confirmed the effective antibacterial activity of the released silver nanoparticles against both gram positive and negative bacteria. Overall, these findings provide economical and simple methods to manufacture stable, hydrogel forming wound dressings that release antibiotic silver over prolonged periods suitable for emergency use in remote locations.


2019 ◽  
Vol 27 (7) ◽  
pp. 1595-1607 ◽  
Author(s):  
Asmaa Selim ◽  
Andras Jozsef Toth ◽  
Daniel Fozer ◽  
Eniko Haaz ◽  
Nóra Valentínyi ◽  
...  

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