Quasi one-dimensional assembly of gold nanoparticles templated by a pH-sensitive peptide amphiphile from silk fibroin

RSC Advances ◽  
2012 ◽  
Vol 2 (13) ◽  
pp. 5599 ◽  
Author(s):  
Jinming Zhang ◽  
Tao Xu ◽  
Jinrong Yao ◽  
Lei Huang ◽  
Xin Chen ◽  
...  
2013 ◽  
Vol 14 (8) ◽  
pp. 2733-2738 ◽  
Author(s):  
Hui Guo ◽  
Jinming Zhang ◽  
Tao Xu ◽  
Zhidong Zhang ◽  
Jinrong Yao ◽  
...  

2021 ◽  
Vol 18 ◽  
Author(s):  
Aykut Elmas ◽  
Guliz Akyuz ◽  
Ayhan Bergal ◽  
Muberra Andac ◽  
Omer Andac

Background: pH sensitive dendrimers attached to nanocarriers, as one of the drug release systems, has become quite popular due to their ease of manufacture in experimental conditions and ability to generate fast drug release in the targeted area. This kind of fast release behavior cannot be represented properly most of the existing kinetic mathematical models. Besides, these models have either no pH dependence or pH dependence added separately. So, they have remained one dimensional. Objective: The aim of this study was to establish the proper analytic equation to describe the fast release of drugs from pH sensitive nanocarrier systems. Then, to combine it with the pH dependent equation for establishing a two-dimensional model for whole system. Methods: We used four common kinetic models for comparison and we fitted them to the release data. Finding that, only Higuchi and Korsmeyer-Peppas models show acceptable fit results. None of these models have pH dependence. To get a better description for pH triggered fast release, we observed the behavior of the slope angle of the release curve. Then we puroposed a new analytic equation by using relation between the slope angle and time. Result: To add a pH dependent equation, we assumed the drug release is “on” or “off” above/below specific pH value and we modified a step function to get a desired behavior. Conclusion: Our new analytic model shows good fitting, not only one-dimensional time dependent release, but also two-dimensional pH dependent release, that provides a useful analytic model to represent release profiles of pH sensitive fast drug release systems.


2001 ◽  
Vol 704 ◽  
Author(s):  
Sheng-Ming Shih ◽  
Wei-Fang Su ◽  
Yuh-Jiuan Lin ◽  
Cen-Shawn Wu ◽  
Chii-Dong Chen

AbstractNovel arrays of gold nanoparticles with sulfur containing fullerene nanoparticles were self-assembled through the formation of Au-S covalent bonds. Disulfide functional groups were introduced into C60 molecule by reacting propyl 2-aminoethyl disulfide with C60. The two dimensional(2D) arrays were formed at the interface of aqueous phase of gold particles and organic phase of fullerene particles as a blue transparent film. TEM images showed that the fullerene spacing between adjacent Au(~10 nm) particles was about 2.1±0.4 nm, which was consistent with the result of 2.18 nm by molecular molding calculations(MM+). The arrays were deposited on the top of pairs of gold electrodes to form 2D colloidal single electron devices. The electrode pairs were made by electron beam lithography techniques, and the separation between tips of the two electrodes in a pair was less then 100 nm. Transport measurements at low temperatures exhibited Coulomb-Blockade type current-voltage characteristics, the lower the temperature the more pronounced the Coulomb gap. Also, step-by-step method was used to assemble one-dimensional(1D) array of gold nanoparticles with fullerene derivative between two electrodes spaced with 15 nm. The Coulomb blockade behavior of 1D arrays was clearer than that of 2D arrays.


2019 ◽  
Vol 13 (2) ◽  
pp. 126-132 ◽  
Author(s):  
Chengzhi Yang ◽  
Shikun Chen ◽  
Huilan Su ◽  
Haoyue Zhang ◽  
Jianfei Tang ◽  
...  

ACS Nano ◽  
2020 ◽  
Vol 14 (5) ◽  
pp. 5874-5886 ◽  
Author(s):  
Elena A. Egorova ◽  
Mark M. J. van Rijt ◽  
Nico Sommerdijk ◽  
Gert S. Gooris ◽  
Joke A. Bouwstra ◽  
...  

2012 ◽  
Vol 20 (3) ◽  
pp. 319-326 ◽  
Author(s):  
Eui-Joon Cha ◽  
In-Cheol Sun ◽  
Sang Cheon Lee ◽  
Kwangmeyung Kim ◽  
Ick Chan Kwon ◽  
...  

ChemPhysChem ◽  
2012 ◽  
Vol 13 (5) ◽  
pp. 1347-1353 ◽  
Author(s):  
Jorge Carballido-Landeira ◽  
Sonia Goy-López ◽  
Alberto P. Muñuzuri ◽  
Pablo Taboada ◽  
Víctor Mosquera

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