A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines

2012 ◽  
Vol 10 (32) ◽  
pp. 6600 ◽  
Author(s):  
Ke Chen ◽  
Sumod A. Pullarkat
Keyword(s):  
Michael Addition ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One

Pyridine-grafted graphene oxide: a reusable acid–base bifunctional catalyst for the one-pot synthesis of β-phosphonomalonates via a cascade Knoevenagel–phospha Michael addition reaction in water

RSC Advances ◽  
2015 ◽  
Vol 5 (117) ◽  
pp. 96532-96538 ◽  
Author(s):  
Sara Sobhani ◽  
Farzaneh Zarifi
Keyword(s):  
Graphene Oxide ◽  
Michael Addition ◽  
Addition Reaction ◽  
Bifunctional Catalyst ◽  
Michael Addition Reaction ◽  
Acid Base ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Reaction In Water

Py–GO as a new acid–base bifunctional catalyst was synthesized and employed for the one-pot synthesis of β-phosphonomalonates in water.

Synthesis of Thermoresponsive Nonconjugated Fluorescent Branched Poly(ether amide)s via Oxa-Michael Addition Polymerization

2021 ◽  
Author(s):  
Qimin Jiang ◽  
Liang Zhao ◽  
Yongzhuang Du ◽  
Wenyan Huang ◽  
Xiaoqiang Xue ◽  
...  
Keyword(s):  
Michael Addition ◽  
Biological Applications ◽  
Stimuli Responsive ◽  
One Pot ◽  
One Pot Synthesis ◽  
Addition Polymerization ◽  
Straightforward Method ◽  
Fluorescent Polymers ◽  
The One ◽  
Michael Addition Polymerization

With the aim of providing a straightforward method for the synthesis of stimuli-responsive nonconjugated fluorescent polymers suitable for biological applications, this study describes the one-pot synthesis of novel thermoresponsive nonconjugated...

A straightforward approach for the one-pot synthesis of cyclic polymers from RAFT polymers via thiol–Michael addition

2016 ◽  
Vol 7 (9) ◽  
pp. 1782-1791 ◽  
Author(s):  
Junfei Zhao ◽  
Yanyan Zhou ◽  
Yu Zhou ◽  
Nianchen Zhou ◽  
Xiangqiang Pan ◽  
...  
Keyword(s):  
Michael Addition ◽  
One Pot ◽  
Cyclic Polymers ◽  
One Pot Synthesis ◽  
The One ◽  
Raft Polymers ◽  
Straightforward Approach

A straightforward approach for the synthesis of cyclic polymers in a one-pot reaction.

An Overview of the One-pot Synthesis of Imidazolines

2020 ◽  
Vol 24 (20) ◽  
pp. 2341-2355
Author(s):  
Thaipparambil Aneeja ◽  
Sankaran Radhika ◽  
Mohan Neetha ◽  
Gopinathan Anilkumar
Keyword(s):  
Asymmetric Catalysis ◽  
Organic Compounds ◽  
Ring Opening ◽  
Ecological Impact ◽  
Chiral Auxiliary ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Synthetic Intermediate ◽  
Heterocyclic Moiety

One-pot syntheses are a simple, efficient and easy methodology, which are widely used for the synthesis of organic compounds. Imidazoline is a valuable heterocyclic moiety used as a synthetic intermediate, chiral auxiliary, chiral catalyst and a ligand for asymmetric catalysis. Imidazole is a fundamental unit of biomolecules that can be easily prepared from imidazolines. The one-pot method is an impressive approach to synthesize organic compounds as it minimizes the reaction time, separation procedures, and ecological impact. Many significant one-pot methods such as N-bromosuccinimide mediated reaction, ring-opening of tetrahydrofuran, triflic anhydrate mediated reaction, etc. were reported for imidazoline synthesis. This review describes an overview of the one-pot synthesis of imidazolines and covers literature up to 2020.

Catalyst-Free One-Pot Synthesis of Novel Heteroarylamine Substituted Furo[3,2-c]coumarins

Synlett ◽  
2018 ◽  
Vol 29 (12) ◽  
pp. 1589-1592 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Mahnaz Saraei ◽  
Reyhaneh Khoeiniha
Keyword(s):  
Michael Addition ◽  
Aldol Condensation ◽  
Ring Closure ◽  
Dehydration Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Tandem Process ◽  
First Time

A high-yielding cyclocondensation of 4-hydroxycoumarin, phenylglyoxal monohydrate, and heteroarylamines proceeds without catalysis, which gives novel functionalized furo[3,2-c]coumarins and heteroarylamino alkylation of coumarin products in acetonitrile under reflux, is reported for the first time. This tandem process involves sequentially an aldol condensation, Michael addition, a ring closure, and dehydration reaction.

One-Pot Synthesis of Highly Substituted Allenylidene Derivatives via Palladium- or Nickel-Catalyzed Tandem Michael Addition-Cyclization Reaction

2009 ◽  
Vol 351 (1-2) ◽  
pp. 141-146 ◽  
Author(s):  
Yun Shi ◽  
Jing Huang ◽  
Yan-Fang Yang ◽  
Lu-Yong Wu ◽  
Yan-Ning Niu ◽  
...  
Keyword(s):  
Michael Addition ◽  
Cyclization Reaction ◽  
One Pot ◽  
One Pot Synthesis
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