scholarly journals Total synthesis of indole-3-acetonitrile-4-methoxy-2-C-β-d-glucopyranoside. Proposal for structural revision of the natural product

2012 ◽  
Vol 10 (27) ◽  
pp. 5194 ◽  
Author(s):  
Akop Yepremyan ◽  
Thomas G. Minehan
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Structural Revision

Bioinspired total synthesis and structural revision of yuremamine, an alkaloid from the entheogenic plant Mimosa tenuiflora

2015 ◽  
Vol 51 (28) ◽  
pp. 6202-6205 ◽  
Author(s):  
Matthew B. Calvert ◽  
Jonathan Sperry
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Synthetic Approach ◽  
Structural Revision ◽  
True Structure ◽  
Mimosa Tenuiflora

A bioinspired synthetic approach to nominal yuremamine has uncovered the true structure of the natural product to be a flavonoidal indole.

Total synthesis and structural revision of an isopanepoxydone analog isolated from Lentinus strigellus

2018 ◽  
Vol 16 (27) ◽  
pp. 5043-5049 ◽  
Author(s):  
Yi Man ◽  
Shaomin Fu ◽  
Juan Chen ◽  
Bo Liu
Keyword(s):  
Molecular Structure ◽  
Total Synthesis ◽  
Natural Product ◽  
Asymmetric Total Synthesis ◽  
Structural Revision

Asymmetric total synthesis of compound 1, as a proposed molecular structure of a natural product, in 11 steps is described. The inconsistency of the characterization data prompted us to propose a different structure as compound 2 and accordingly accomplish total synthesis in 9 steps and confirm the structural revision of this natural product.

Total Synthesis and Structural Revision of a Harziane Diterpenoid

2019 ◽  
Author(s):  
Moritz Honig ◽  
Erick Carreira
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Spectral Characteristics ◽  
Tertiary Alcohol ◽  
Carbon Skeleton ◽  
Structural Revision ◽  
Stereochemical Analysis ◽  
Quaternary Stereocenter

The first total synthesis of nominal harziane diterpenoid is disclosed, whose spectral characteristics did not match those of the reported natural product. Stereochemical analysis and subsequent synthesis of the epimeric tertiary alcohol led to reassignment of configuration of the natural product. At the heart of the synthesis is an enyne cycloisomerization that sets a key quaternary stereocenter within a cyclobutane with high diastereocontrol. The route features strategies for the synthesis of the highly congested 6–5–7–4 carbon skeleton characteristic of the caged harziane diterpenoids.

scholarly journals Total Synthesis and Structural Revision of a Harziane Diterpenoid

2019 ◽  
Author(s):  
Moritz Honig ◽  
Erick Carreira
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Spectral Characteristics ◽  
Tertiary Alcohol ◽  
Carbon Skeleton ◽  
Structural Revision ◽  
Stereochemical Analysis ◽  
Quaternary Stereocenter

The first total synthesis of nominal harziane diterpenoid is disclosed, whose spectral characteristics did not match those of the reported natural product. Stereochemical analysis and subsequent synthesis of the epimeric tertiary alcohol led to reassignment of configuration of the natural product. At the heart of the synthesis is an enyne cycloisomerization that sets a key quaternary stereocenter within a cyclobutane with high diastereocontrol. The route features strategies for the synthesis of the highly congested 6–5–7–4 carbon skeleton characteristic of the caged harziane diterpenoids.

Total Synthesis and Structural Revision of Mycalol, an Anticancer Natural Product from the Marine Source

2015 ◽  
Vol 17 (7) ◽  
pp. 1652-1655 ◽  
Author(s):  
B. Seetharamsingh ◽  
P. R. Rajamohanan ◽  
D. Srinivasa Reddy
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Structural Revision ◽  
Marine Source

ChemInform Abstract: Total Synthesis and Structural Revision of Mycalol, an Anticancer Natural Product from the Marine Source.

ChemInform ◽  
2015 ◽  
Vol 46 (34) ◽  
pp. no-no
Author(s):  
B. Seetharamsingh ◽  
P. R. Rajamohanan ◽  
D. Srinivasa Reddy
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Structural Revision ◽  
Marine Source

Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation

2018 ◽  
Vol 16 (47) ◽  
pp. 9138-9142 ◽  
Author(s):  
Gorakhnath R. Jachak ◽  
Paresh R. Athawale ◽  
Heena Agarwal ◽  
Manoj Kumar Barthwal ◽  
Gianluigi Lauro ◽  
...  
Keyword(s):  
Biological Activity ◽  
Total Synthesis ◽  
Natural Product ◽  
Structural Revision ◽  
Activity Evaluation ◽  
Anti Inflammatory ◽  
First Time

Herein, we report the total synthesis of solomonamide A along with its structural revision for the first time.

Synthetic studies toward inducamide C

2021 ◽  
Author(s):  
Ardalan A. Nabi ◽  
Lydia M. Scott ◽  
Daniel P. Furkert ◽  
Jonathan Sperry
Keyword(s):  
Natural Product ◽  
Structural Revision ◽  
Synthetic Studies

The rare benzoxazepine ring in the alkaloid inducamide C is unstable and prone to rearrangement, indicating that structural revision of the natural product may be necessary.

Progress Toward The Total Synthesis Of The Marine Natural Product Karlotoxin 5

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
M Albadry ◽  
Y Zou ◽  
Y Takahashi ◽  
A Waters ◽  
M Hossein ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Marine Natural Product
Sign in / Sign up

Export Citation Format

Share Document