Isolation, antimicrobial activity, and absolute configuration of the furylidene tetronic acid core of pestalotic acids A–G

2012 ◽  
Vol 10 (27) ◽  
pp. 5307 ◽  
Author(s):  
Fan Zhang ◽  
Gang Ding ◽  
Li Li ◽  
Xiaoyue Cai ◽  
Yikang Si ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Absolute Configuration ◽  
Tetronic Acid

New rare atropisomers: structure elucidation, absolute configuration and antimicrobial activity

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
A Debbab ◽  
R Bara ◽  
A Pretsch ◽  
R Edrada Ebel ◽  
V Wray ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Absolute Configuration ◽  
Structure Elucidation

Absolute Configuration and Antimicrobial Activity of Acylhomoserine Lactones

2008 ◽  
Vol 71 (6) ◽  
pp. 1032-1036 ◽  
Author(s):  
Armando M. Pomini ◽  
Anita J. Marsaioli
Keyword(s):  
Antimicrobial Activity ◽  
Absolute Configuration

Microbial Transformation of (−)-Carvone¥

2004 ◽  
Vol 59 (5-6) ◽  
pp. 389-392 ◽  
Author(s):  
Fatih Demirci ◽  
Yoshiaki Noma ◽  
Neş’e Kırımer ◽  
K. Hüsnü Can Başera
Keyword(s):  
Antimicrobial Activity ◽  
Absolute Configuration ◽  
Pathogenic Fungus ◽  
Microbial Transformation ◽  
Crystalline Substance ◽  
Spectroscopic Techniques ◽  
Pathogenic Microorganisms ◽  
X Ray Diffraction ◽  
X Ray ◽  
Plant Pathogenic Fungus

The cyclic monoterpene ketone (−)-carvone was metabolized by the plant pathogenic fungus Absidia glauca. After 4 days of incubation, the diol 10-hydroxy-(+)-neodihydrocarveol was formed. The absolute configuration and structure of the crystalline substance was identified by means of X-ray diffraction and by spectroscopic techniques (MS, IR and NMR). The antimicrobial activity of the substrate and metabolite was assayed with human pathogenic microorganisms.

A New Sesterterpene Tetronic Acid From an Australian Sponge, Ircinia sp

1987 ◽  
Vol 40 (7) ◽  
pp. 1327 ◽  
Author(s):  
RJ Capon ◽  
JK Macleod
Keyword(s):  
Antimicrobial Activity ◽  
Structure Elucidation ◽  
Spectroscopic Analysis ◽  
Tetronic Acid

A new sesterterpene tetronic acid* (2), exhibiting antimicrobial activity, has been isolated from an Australian Ircinia species. The structure elucidation was based on detailed spectroscopic analysis of (2), its acetate (3), and two methylated derivatives (4) and (5).

A New Sesterterpene Tetronic Acid From an Australian Marine Sponge, Psammocinia sp.

1995 ◽  
Vol 48 (11) ◽  
pp. 1899 ◽  
Author(s):  
L Murray ◽  
H Hamit ◽  
JNA Hooper ◽  
L Hobbs ◽  
RJ Capon
Keyword(s):  
Antimicrobial Activity ◽  
Natural Product ◽  
Marine Sponge ◽  
Spectroscopic Analysis ◽  
Marine Natural Product ◽  
Structural Isomer ◽  
Tetronic Acid ◽  
Spectroscopic Characteristics

A new sesterterpene tetronic acid (5) exhibiting antimicrobial activity has been isolated from an Australian marine sponge, Psammocinia sp., and its structure secured by detailed spectroscopic analysis. The tetronic acid (5) possesses almost identical spectroscopic characteristics to, and is a structural isomer of, the known marine natural product (6) previously reported from an Australian sponge.

scholarly journals Antibacterial Cyclic Tripeptides from Antarctica-Sponge-Derived Fungus Aspergillus insulicola HDN151418

Marine Drugs ◽  
2020 ◽  
Vol 18 (11) ◽  
pp. 532
Author(s):  
Chunxiao Sun ◽  
Ziping Zhang ◽  
Zilin Ren ◽  
Liu Yu ◽  
Huan Zhou ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Ethyl Acetate ◽  
Absolute Configuration ◽  
Ethyl Acetate Extract ◽  
Edwardsiella Tarda ◽  
Side Chain ◽  
Mycobacterium Phlei ◽  
Vibrio Parahemolyticus ◽  
First Time

Three new aspochracin-type cyclic tripeptides, sclerotiotides M–O (1–3), together with three known analogues, sclerotiotide L (4), sclerotiotide F (5), and sclerotiotide B (6), were obtained from the ethyl acetate extract of the fungus Aspergillus insulicola HDN151418, which was isolated from an unidentified Antarctica sponge. Spectroscopic and chemical approaches were used to elucidate their structures. The absolute configuration of the side chain in compound 4 was elucidated for the first time. Compounds 1 and 2 showed broad antimicrobial activity against a panel of pathogenic strains, including Bacillus cereus, Proteus species, Mycobacterium phlei, Bacillus subtilis, Vibrio parahemolyticus, Edwardsiella tarda, MRCNS, and MRSA, with MIC values ranging from 1.56 to 25.0 µM.

A highly asymmetric synthesis of the O-2-isocephem class of β-lactam antibiotics

1980 ◽  
Vol 58 (15) ◽  
pp. 1605-1607 ◽  
Author(s):  
Sheila M. Tenneson ◽  
Bernard Belleau
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Asymmetric Synthesis ◽  
Absolute Configuration ◽  
Optical Yield ◽  
The Absolute

Starting from D-threonine, an asymmetric synthesis of the dextrorotatory bioactive enantiomer of 3-methyl-7-phenylacetamido-O-2-isocephem was accomplished. The key step, where asymmetric cycloaddition of azidoacetyl chloride to the cinnamylidene Schiff base of protected D-threonine is induced, generates the desired cis-β-lactam in 90% optical yield. The absolute configuration of the final product was confirmed by comparing its antimicrobial activity with that of its corresponding racemate.

A New Furanosesterpene From the Marine Sponge Psammocinia rugosa

1989 ◽  
Vol 42 (10) ◽  
pp. 1805 ◽  
Author(s):  
V Liokas ◽  
MJ Garson ◽  
JA Carver
Keyword(s):  
Antimicrobial Activity ◽  
Marine Sponge ◽  
Tetronic Acid

A tetronic acid (5), 5-[13-(furan-3-yl)-2,6,10-trimethyltrideca-2,6,8-trienyl]-4-hydroxy 3-methylfuran-2(5H)-one,* with weak antimicrobial activity has been isolated from the sponge Psammocinia sp. and characterized by analysis of 1H and 13C n.m.r. data including 'H-1H correlation (COSY) experiments. The compound may be identical to a tetronic acid isolated by the Roche group, previously assigned structure (3).

Antimicrobial activity of withanolides from the leaves of Withania aristata

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
L Araujo ◽  
N Padilla ◽  
GG Llanos ◽  
IL Bazzocchi ◽  
L Moujir
Keyword(s):  
Antimicrobial Activity
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