A new synthetic route for axially chiral secondary amines with binaphthyl backbone and their applications in asymmetric Michael reaction of aldehydes to nitroalkenes

2012 ◽  
Vol 10 (15) ◽  
pp. 3071 ◽  
Author(s):  
Da-Cheng Liang ◽  
Ren-Shi Luo ◽  
Li-Hua Yin ◽  
Albert S. C. Chan ◽  
Gui Lu
Keyword(s):  
Michael Reaction ◽  
Secondary Amines ◽  
Synthetic Route ◽  
Axially Chiral ◽  
Asymmetric Michael Reaction

scholarly journals Copper-Catalyzed Synthesis of Axially Chiral Biaryls with Diaryliodonium Salts as Arylation Reagents

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3223
Author(s):  
Ji-Wei Zhang ◽  
Shao-Hua Xiang ◽  
Shaoyu Li ◽  
Bin Tan
Keyword(s):  
Amino Alcohols ◽  
Sigmatropic Rearrangement ◽  
Synthetic Route ◽  
Mild Conditions ◽  
Good Substrate ◽  
Diaryliodonium Salts ◽  
Axially Chiral

NOBIN and BINAM derivatives harboring biaryl frameworks are recognized as a class of important atropisomers with versatile applications. Here, we present an efficient synthetic route to access such compounds through copper-catalyzed domino arylation of N-arylhydroxylamines or N-arylhydrazines with diaryliodonium salts and [3,3]-sigmatropic rearrangement. This reaction features mild conditions, good substrate compatibility, and excellent efficiency. The practicality of this protocol was further extended by the synthesis of biaryl amino alcohols.

ChemInform Abstract: High Diastereoselectivity Induced by a Fluorous Alkyl Group in the Asymmetric Michael Reaction of Nitroalkenes Catalyzed by a Prolinol Methyl Ether.

ChemInform ◽  
2014 ◽  
Vol 45 (18) ◽  
pp. no-no
Author(s):  
Kazumasa Funabiki ◽  
Masaya Ohta ◽  
Yuta Sakaida ◽  
Kiyofumi Oida ◽  
Yasuhiro Kubota ◽  
...  
Keyword(s):  
Methyl Ether ◽  
Alkyl Group ◽  
Michael Reaction ◽  
Asymmetric Michael Reaction

Cationic [2,6-Bis(2‘-oxazolinyl)phenyl]palladium(II) Complexes:  Catalysts for the Asymmetric Michael Reaction

2000 ◽  
Vol 19 (7) ◽  
pp. 1282-1291 ◽  
Author(s):  
Mark A. Stark ◽  
Geraint Jones ◽  
Christopher J. Richards
Keyword(s):  
Michael Reaction ◽  
Asymmetric Michael Reaction

2-Azanorbornane-Based Amino Alcohol Organocatalysts for Asymmetric Michael Reaction of β-Keto Esters with Nitroolefins

2019 ◽  
Vol 2019 (24) ◽  
pp. 3882-3889 ◽  
Author(s):  
Rei Togashi ◽  
Madhu Chennapuram ◽  
Chigusa Seki ◽  
Yuko Okuyama ◽  
Eunsang Kwon ◽  
...  
Keyword(s):  
Amino Alcohol ◽  
Michael Reaction ◽  
Keto Esters ◽  
Asymmetric Michael Reaction

Asymmetric Michael reaction between aldehydes and nitroalkanes promoted by pyrrolidine-containing C2-symmetric organocatalysts

2019 ◽  
Vol 68 (7) ◽  
pp. 1402-1406
Author(s):  
K. A. Bykova ◽  
A. A. Kostenko ◽  
A. S. Kucherenko ◽  
S. G. Zlotin
Keyword(s):  
Michael Reaction ◽  
Asymmetric Michael Reaction

ChemInform Abstract: Asymmetric Michael Reaction of Acetaldehyde Catalyzed by Diphenylprolinol Silyl Ether.

ChemInform ◽  
2008 ◽  
Vol 39 (41) ◽  
Author(s):  
Yujiro Hayashi ◽  
Takahiko Itoh ◽  
Masahiro Ohkubo ◽  
Hayato Ishikawa
Keyword(s):  
Michael Reaction ◽  
Silyl Ether ◽  
Asymmetric Michael Reaction
Sign in / Sign up

Export Citation Format

Share Document