Genome-wide transcriptional responses of Escherichia coli to glyphosate, a potent inhibitor of the shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase

2013 ◽  
Vol 9 (3) ◽  
pp. 522-530 ◽  
Author(s):  
Wei Lu ◽  
Liang Li ◽  
Ming Chen ◽  
Zhengfu Zhou ◽  
Wei Zhang ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Potent Inhibitor ◽  
Shikimate Pathway ◽  
Transcriptional Responses ◽  
Genome Wide ◽  
Phosphate Synthase

Genome-wide transcriptional responses of Escherichia coli to recombinant protein overproduction

2007 ◽  
Vol 131 (2) ◽  
pp. S17
Author(s):  
Min Jee Kim ◽  
Soo Jung Park ◽  
Doo-Byoung Oh ◽  
Hyun Ah Kang ◽  
Ohsuk Kwon
Keyword(s):  
Escherichia Coli ◽  
Recombinant Protein ◽  
Transcriptional Responses ◽  
Genome Wide ◽  
Protein Overproduction

scholarly journals Genome-Wide Transcriptional Responses of Escherichia coli K-12 to Continuous Osmotic and Heat Stresses

2008 ◽  
Vol 190 (10) ◽  
pp. 3712-3720 ◽  
Author(s):  
Thusitha S. Gunasekera ◽  
Laszlo N. Csonka ◽  
Oleg Paliy
Keyword(s):  
Oxidative Stress ◽  
Escherichia Coli ◽  
High Temperature ◽  
Osmotic Stress ◽  
Stress Responses ◽  
Transcriptional Responses ◽  
High Osmolarity ◽  
Genome Wide ◽  
K 12 ◽  
And Oxidative Stress

ABSTRACT Osmotic stress is known to increase the thermotolerance and oxidative-stress resistance of bacteria by a mechanism that is not adequately understood. We probed the cross-regulation of continuous osmotic and heat stress responses by characterizing the effects of external osmolarity (0.3 M versus 0.0 M NaCl) and temperature (43°C versus 30°C) on the transcriptome of Escherichia coli K-12. Our most important discovery was that a number of genes in the SoxRS and OxyR oxidative-stress regulons were up-regulated by high osmolarity, high temperature, or a combination of both stresses. This result can explain the previously noted cross-protection of osmotic stress against oxidative and heat stresses. Most of the genes shown in previous studies to be induced during the early phase of adaptation to hyperosmotic shock were found to be also overexpressed under continuous osmotic stress. However, there was a poorer overlap between the heat shock genes that are induced transiently after high temperature shifts and the genes that we found to be chronically up-regulated at 43°C. Supplementation of the high-osmolarity medium with the osmoprotectant glycine betaine, which reduces the cytoplasmic K+ pool, did not lead to a universal reduction in the expression of osmotically induced genes. This finding does not support the hypothesis that K+ is the central osmoregulatory signal in Enterobacteriaceae.

Genome-wide investigation on transcriptional responses to drought stress in wild and cultivated rice

2021 ◽  
pp. 104555
Author(s):  
Mu-Fan Geng ◽  
Xiu-Hua Wang ◽  
Mei-Xia Wang ◽  
Zhe Cai ◽  
Qing-Lin Meng ◽  
...  
Keyword(s):  
Drought Stress ◽  
Cultivated Rice ◽  
Transcriptional Responses ◽  
Genome Wide
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