De novo sequencing and characterization of a novel Bowman–Birk inhibitor from Lathyrus sativus L. seeds by electrospray mass spectrometry

2012 ◽  
Vol 8 (12) ◽  
pp. 3232 ◽  
Author(s):  
Rachele Tamburino ◽  
Valeria Severino ◽  
Annamaria Sandomenico ◽  
Menotti Ruvo ◽  
Augusto Parente ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
De Novo ◽  
De Novo Sequencing ◽  
Lathyrus Sativus ◽  
Lathyrus Sativus L

ON PREPROCESSING AND ANTISYMMETRY IN DE NOVO PEPTIDE SEQUENCING: IMPROVING EFFICIENCY AND ACCURACY

2008 ◽  
Vol 06 (03) ◽  
pp. 467-492 ◽  
Author(s):  
KANG NING ◽  
NAN YE ◽  
HON WAI LEONG
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Computational Models ◽  
De Novo ◽  
Noise Removal ◽  
Peptide Sequencing ◽  
De Novo Sequencing ◽  
Tandem Mass ◽  
De Novo Peptide Sequencing ◽  
De Novo Peptide

Peptide sequencing plays a fundamental role in proteomics. Tandem mass spectrometry, being sensitive and efficient, is one of the most commonly used techniques in peptide sequencing. Many computational models and algorithms have been developed for peptide sequencing using tandem mass spectrometry. In this paper, we investigate general issues in de novo sequencing, and present results that can be used to improve current de novo sequencing algorithms. We propose a general preprocessing scheme that performs binning, pseudo-peak introduction, and noise removal, and present theoretical and experimental analyses on each of the components. Then, we study the antisymmetry problem and current assumptions related to it, and propose a more realistic way to handle the antisymmetry problem based on analysis of some datasets. We integrate our findings on preprocessing and the antisymmetry problem with some current models for peptide sequencing. Experimental results show that our findings help to improve accuracies for de novo sequencing.

Electrospray mass spectrometry for the characterization of the purity of natural and modified oligodeoxynucleotides

1995 ◽  
Vol 9 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Alain Deroussent ◽  
Jean-Pierre Le Caer ◽  
Jean Rossier ◽  
Alain Gouyette
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry

Characterization of multimetallic grid-type complexes by electrospray mass spectrometry

2002 ◽  
Vol 37 (1) ◽  
pp. 56-62 ◽  
Author(s):  
H�l�ne Nierengarten ◽  
Emmanuelle Leize ◽  
Esther Breuning ◽  
Ana Garcia ◽  
Francisco Romero-Salguero ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry

Electrospray mass spectrometry in the structural characterization of cephalosporins

1999 ◽  
Vol 34 (4) ◽  
pp. 268-275 ◽  
Author(s):  
Simone Tenconi ◽  
Laura De Filippo ◽  
Marco Da Col ◽  
Anna Maria Gioacchini ◽  
Pietro Traldi
Keyword(s):  
Mass Spectrometry ◽  
Structural Characterization ◽  
Electrospray Mass Spectrometry
Sign in / Sign up

Export Citation Format

Share Document