Drug–target interaction prediction by random walk on the heterogeneous network

2012 ◽  
Vol 8 (7) ◽  
pp. 1970 ◽  
Author(s):  
Xing Chen ◽  
Ming-Xi Liu ◽  
Gui-Ying Yan
Keyword(s):  
Random Walk ◽  
Heterogeneous Network ◽  
Drug Target ◽  
Target Interaction ◽  
Interaction Prediction

Drug-Target Interaction Prediction with Graph Regularized Matrix Factorization

2017 ◽  
Vol 14 (3) ◽  
pp. 646-656 ◽  
Author(s):  
Ali Ezzat ◽  
Peilin Zhao ◽  
Min Wu ◽  
Xiao-Li Li ◽  
Chee-Keong Kwoh
Keyword(s):  
Matrix Factorization ◽  
Drug Target ◽  
Target Interaction ◽  
Interaction Prediction

Prediction of drug–target interaction by label propagation with mutual interaction information derived from heterogeneous network

2016 ◽  
Vol 12 (2) ◽  
pp. 520-531 ◽  
Author(s):  
Xiao-Ying Yan ◽  
Shao-Wu Zhang ◽  
Song-Yao Zhang
Keyword(s):  
Heterogeneous Network ◽  
Drug Target ◽  
Label Propagation ◽  
Mutual Interaction ◽  
Potential Drug Target ◽  
Potential Drug ◽  
Similarity Network ◽  
Target Interaction ◽  
Interaction Information

By implementing label propagation on drug/target similarity network with mutual interaction information derived from drug–target heterogeneous network, LPMIHN algorithm identifies potential drug–target interactions.

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