scholarly journals Rapid determination of vitamin B12 concentration with a chemiluminescence lab on a chip

Lab on a Chip ◽  
2012 ◽  
Vol 12 (13) ◽  
pp. 2353 ◽  
Author(s):  
Khoi Seng Lok ◽  
Siti Zubaidah binte Abdul Muttalib ◽  
Peter Peng Foo Lee ◽  
Yien Chian Kwok ◽  
Nam-Trung Nguyen
2016 ◽  
Vol 8 (22) ◽  
pp. 4324-4327 ◽  
Author(s):  
Fei Qu ◽  
Qianwei Song ◽  
Jinmao You

Ag nanocluster fluorescence can be dramatically quenched by vitamin B12 by the inner filter effect.


2017 ◽  
Vol 15 (7) ◽  
pp. 529-539
Author(s):  
Thanyaluck SOMSAENG ◽  
Kem PUMSA-ARD ◽  
Piyada JITTANGPRASERT

A simple lab-on-a-chip system was developed for the rapid determination of ethanol in different sample matrices, including gasohol and various alcoholic beverages. The colorimetric detection of ethanol using a spectrophotometer was based on the reaction between ethanol with 0.12 M ceric ammonium nitrate in acidic medium to produce a red colored product which gave a maximum absorption at 470 nm. A non-lithographic method was used for creating lab-on-a-chip molds to reduce  manufacturing cost and preparation steps. The lab-on-a-chip device was fabricated from polydimethylsiloxane which consisted of a simple Y-shaped working channel. Under optimum conditions, a linear calibration graph was obtained in the concentration range of 0.20 - 20 % (v/v) (r2> 0.999). The limit of detection (3 SD) and limit of quantification (10 SD) were 0.039 and 0.13 % (v/v), respectively. The precision reported in terms of relative standard deviation (RSD) values was less than 1.40 % (n = 15). To demonstrate the lab-on-a-chip’s performance, the determination of ethanol in gasohol and various alcoholic beverages was applied. The results obtained from the developed method compared with a standard gas chromatographic method were well correlated using the paired t-test and linear regression test. The results indicate that the proposed method has shown potential to extend the use of this simple lab-on-a-chip analytical device, due to its simplicity, low cost, lower reagent and sample consumption and high analytical performance. Moreover, the method of fabrication would be an additive manufacturing technique featuring a low equipment cost with no need for clean rooms.


2012 ◽  
Vol 4 (12) ◽  
pp. 4155 ◽  
Author(s):  
Fayezeh Samari ◽  
Bahram Hemmateenejad ◽  
Zahra Rezaei ◽  
Mojtaba Shamsipur

Author(s):  
T. Y. Tan ◽  
W. K. Tice

In studying ion implanted semiconductors and fast neutron irradiated metals, the need for characterizing small dislocation loops having diameters of a few hundred angstrom units usually arises. The weak beam imaging method is a powerful technique for analyzing these loops. Because of the large reduction in stacking fault (SF) fringe spacing at large sg, this method allows for a rapid determination of whether the loop is faulted, and, hence, whether it is a perfect or a Frank partial loop. This method was first used by Bicknell to image small faulted loops in boron implanted silicon. He explained the fringe spacing by kinematical theory, i.e., ≃l/(Sg) in the fault fringe in depth oscillation. The fault image contrast formation mechanism is, however, really more complicated.


2017 ◽  
Vol 45 (2) ◽  
pp. 455-464
Author(s):  
T.T. Xue ◽  
J. Liu ◽  
Y.B. Shen ◽  
G.Q. Liu

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