A facile preparation of targetable pH-sensitive polymeric nanocarriers with encapsulated magnetic nanoparticles for controlled drug release

2012 ◽  
Vol 22 (48) ◽  
pp. 25354 ◽  
Author(s):  
Shun Yang ◽  
Dongyun Chen ◽  
Najun Li ◽  
Xiao Mei ◽  
Xiuxiu Qi ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Polymeric Nanocarriers ◽  
Facile Preparation

A facile way to prepare magnetic nanoparticles encapsulated by targetable pH-sensitive copolymer for controlled drug release

2013 ◽  
Vol 172 (1) ◽  
pp. e66-e67
Author(s):  
Shun Yang ◽  
Najun Li ◽  
Dongyun Chen ◽  
Hua Li ◽  
Xiaoping Xu ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Controlled Drug Release ◽  
Ph Sensitive

scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Core Shell ◽  
Assembly Process ◽  
Block Polymer ◽  
Hollow Mesoporous Silica

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

scholarly journals Carbon-Based Magnetic Nanocarrier for Controlled Drug Release: A Green Synthesis Approach

2018 ◽  
Vol 5 (1) ◽  
pp. 1 ◽  
Author(s):  
Jessica Oliveira ◽  
Raquel Rodrigues ◽  
Lillian Barros ◽  
Isabel Ferreira ◽  
Luís Marchesi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Phosphate Buffer ◽  
Colloidal Stability ◽  
Ph Dependence ◽  
Phosphate Buffer Solution ◽  
Controlled Drug Release ◽  
Buffer Solution ◽  
Carbon Based

In this study, hydrophilic magnetic nanoparticles were synthesized by green routes using a methanolic extract of Rubus ulmifolius Schott flowers. The prepared magnetic nanoparticles were coated with carbon-based shell for drug delivery application. The nanocomposites were further chemically functionalized with nitric acid and, sequentially, with Pluronic® F68 (CMNPs-plur) to enhance their colloidal stability. The resulting material was dispersed in phosphate buffer solution at pH 7.4 to study the Doxorubicin loading. After shaking for 48 h, 99.13% of the drug was loaded by the nanocomposites. Subsequently, the drug release was studied in different working phosphate buffer solutions (i.e., PB pH 4.5, pH 6.0 and pH 7.4) to determine the efficiency of the synthesized material for drug delivery as pH-dependent drug nanocarrier. The results have shown a drug release quantity 18% higher in mimicking tumor environment than in the physiological one. Therefore, this study demonstrates the ability of CMNPs-plur to release a drug with pH dependence, which could be used in the future for the treatment of cancer "in situ" by means of controlled drug release.

Manipulation of pH-Sensitive interactions between podophyllotoxin-chitosan for enhanced controlled drug release

2017 ◽  
Vol 95 ◽  
pp. 451-461 ◽  
Author(s):  
Chao Chen ◽  
Yong Yu ◽  
Xiaoli Wang ◽  
Ping Shi ◽  
Yibing Wang ◽  
...  
Keyword(s):  
Drug Release ◽  
Controlled Drug Release ◽  
Ph Sensitive

Molecular encapsulator on the surface of magnetic nanoparticles. Controlled drug release from calcium Ferrite/Cyclodextrin–tethered polymer hybrid

2018 ◽  
Vol 161 ◽  
pp. 347-355 ◽  
Author(s):  
Sivaraj Ramasamy ◽  
Beniya Samathanam ◽  
Helfried Reuther ◽  
Muthukumar Nadar Meenakshi Subbaraman Adyanpuram ◽  
Israel Vijayaraj Muthu Vijayan Enoch ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Controlled Drug Release ◽  
Calcium Ferrite ◽  
Polymer Hybrid

Monoolein Cubic Phase Gels and Cubosomes Doped with Magnetic Nanoparticles–Hybrid Materials for Controlled Drug Release

2017 ◽  
Vol 9 (3) ◽  
pp. 2796-2805 ◽  
Author(s):  
Monika Szlezak ◽  
Dorota Nieciecka ◽  
Aleksandra Joniec ◽  
Marek Pękała ◽  
Ewa Gorecka ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Hybrid Materials ◽  
Controlled Drug Release ◽  
Cubic Phase

Triple Redox Responsive Poly(Ethylene Glycol)-Polycaprolactone Polymeric Nanocarriers for Fine-Controlled Drug Release

2016 ◽  
Vol 17 (4) ◽  
pp. 1600295 ◽  
Author(s):  
Caiyan Zhao ◽  
Leihou Shao ◽  
Jianqing Lu ◽  
Chenying Zhao ◽  
Yujie Wei ◽  
...  
Keyword(s):  
Drug Release ◽  
Ethylene Glycol ◽  
Controlled Drug Release ◽  
Poly Ethylene Glycol ◽  
Polymeric Nanocarriers ◽  
Redox Responsive ◽  
Poly Ethylene
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