Thiamine hydrochloride (VB1): an efficient promoter for the one-pot synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine and [1,2,4]triazolo[1,5-a]pyrimidine derivatives in water medium

2012 ◽  
Vol 14 (3) ◽  
pp. 840 ◽  
Author(s):  
Junhua Liu ◽  
Min Lei ◽  
Lihong Hu
Keyword(s):  
Thiamine Hydrochloride ◽  
Water Medium ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One

Thiamine hydrochloride (VB1) as an efficient promoter for the one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones

2012 ◽  
Vol 53 (44) ◽  
pp. 5923-5925 ◽  
Author(s):  
Yijia Chen ◽  
Weiguang Shan ◽  
Min Lei ◽  
Lihong Hu
Keyword(s):  
Thiamine Hydrochloride ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One

scholarly journals One-pot synthesis of new Pyrido [2,3-d] Pyrimidine derivatives under ultrasonic irradiation using organo catalyst 4-Dimethylaminopyridine (DMAP)

2016 ◽  
Vol 3 (1) ◽  
Author(s):  
Imtiyaz Rasool Parrey ◽  
Athar Adil Hashmi
Keyword(s):  
Ultrasonic Irradiation ◽  
Aromatic Aldehydes ◽  
Major Effect ◽  
Mass Spectral Data ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Environment Friendly ◽  
Mass Spectral ◽  
One Pot Synthesis ◽  
The One

AbstractThe one-pot synthesis of pyrido[2,3-d] pyrimidine derivatives has been reported via Knoevenagel-Michal addition pathways using substituted aromatic aldehydes, Cyanoacetamide and 6-aminouracil in N,N-dimethylformamide (DMF) solvent, with 4-dimethylaminopyridine (DMAP) as new organo catalyst catalyst under ultrasonic irradiation. The results showed that a series of aromatic aldehydes were effectively used to prepare the targeted pyrido [2, 3-d] pyrimidine derivatives with good to excellent yields (81-93 %) with no major effect on the yield of product by electron donating/withdrawing substituents. Short reaction time, environment friendly procedure, excellent yields, inexpensive and readily available catalyst are the advantages of this procedure. All synthesized compounds were characterized by IR, 1HNMR, 13CNMR and mass spectral data.

An Overview of the One-pot Synthesis of Imidazolines

2020 ◽  
Vol 24 (20) ◽  
pp. 2341-2355
Author(s):  
Thaipparambil Aneeja ◽  
Sankaran Radhika ◽  
Mohan Neetha ◽  
Gopinathan Anilkumar
Keyword(s):  
Asymmetric Catalysis ◽  
Organic Compounds ◽  
Ring Opening ◽  
Ecological Impact ◽  
Chiral Auxiliary ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Synthetic Intermediate ◽  
Heterocyclic Moiety

One-pot syntheses are a simple, efficient and easy methodology, which are widely used for the synthesis of organic compounds. Imidazoline is a valuable heterocyclic moiety used as a synthetic intermediate, chiral auxiliary, chiral catalyst and a ligand for asymmetric catalysis. Imidazole is a fundamental unit of biomolecules that can be easily prepared from imidazolines. The one-pot method is an impressive approach to synthesize organic compounds as it minimizes the reaction time, separation procedures, and ecological impact. Many significant one-pot methods such as N-bromosuccinimide mediated reaction, ring-opening of tetrahydrofuran, triflic anhydrate mediated reaction, etc. were reported for imidazoline synthesis. This review describes an overview of the one-pot synthesis of imidazolines and covers literature up to 2020.

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