Long-term fate of polycyclic aromatic hydrocarbons (PAH) in sediments from Loch Leven after closure of an aluminium smelter

2012 ◽  
Vol 14 (5) ◽  
pp. 1335 ◽  
Author(s):  
A. D. McIntosh ◽  
R. J. Fryer ◽  
L. Webster ◽  
A. B. Cundy
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Loch Leven ◽  
Aluminium Smelter ◽  
Polycyclic Aromatic

scholarly journals Polycyclic aromatic hydrocarbons in biochar amended soils: Long-term experiments in Brazilian tropical areas

Chemosphere ◽  
2018 ◽  
Vol 200 ◽  
pp. 641-648 ◽  
Author(s):  
Michele Fabri de Resende ◽  
Taila Figueredo Brasil ◽  
Beata Emoke Madari ◽  
Annibal Duarte Pereira Netto ◽  
Etelvino Henrique Novotny
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Amended Soils ◽  
Long Term Experiments ◽  
Polycyclic Aromatic ◽  
Tropical Areas

scholarly journals Polycyclic Aromatic Hydrocarbons in Electrocautery Smoke during Peritonectomy Procedures

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Sara Näslund Andréasson ◽  
Haile Mahteme ◽  
Bo Sahlberg ◽  
Helena Anundi
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Occupational Exposure Limits ◽  
Exposure Limits ◽  
Polycyclic Aromatic ◽  
Peritonectomy Procedures ◽  
Low Levels ◽  
Stationary Sampling ◽  
Electrocautery Smoke

Objective. This study identified and quantified polycyclic aromatic hydrocarbons (PAHs) in electrocautery smoke during 40 peritonectomy procedures and investigated any correlations and/or differences between levels of PAHs and perioperative variables.Methods. PAHs were measured in personal and stationary sampling by 40 mm Millipore cassettes, for adsorption of both gaseous and particle-bound PAHs.Results. All 16 USEPA priority pollutant PAHs were detected during peritonectomy procedures, naphthalene being the most abundant. For the only two PAHs with Swedish occupational exposure limits (OELs), benzo[a]pyrene and naphthalene, limits were never exceeded. Amount of bleeding was the only perioperative variable that correlated with levels of PAHs.Conclusions. Low levels of PAHs were detected in electrocautery smoke during peritonectomy procedures, and an increased amount of bleeding correlated with higher levels of PAHs. For evaluation of long-term health effects, more studies are needed.

scholarly journals Short-term and Long-term Exposure of the MucilAir™ Model to Polycyclic Aromatic Hydrocarbons

2019 ◽  
Vol 47 (1) ◽  
pp. 9-18 ◽  
Author(s):  
Tereza Cervena ◽  
Kristyna Vrbova ◽  
Andrea Rossnerova ◽  
Jan Topinka ◽  
Pavel Rossner
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Lung Tissue ◽  
Aromatic Hydrocarbons ◽  
Messenger Rna ◽  
Mrna Levels ◽  
Short Term ◽  
Polycyclic Aromatic ◽  
Ldh Release

Cells grown in monocultures are widely used to model lung tissue. As a result of these culture conditions, these cells exhibit poor morphological similarity to those present in in vivo lung tissue. MucilAir™, a 3-D in vitro model comprising human basal, goblet and ciliated cells, represents a fully differentiated respiratory epithelium that can be used as an alternative and a more realistic system. The aim of our study was to compare the effects of short-term and long-term exposure to two polycyclic aromatic hydrocarbons (PAHs) — benzo[a]pyrene (B[a]P) and 3-nitrobenzanthrone (3-NBA) — using MucilAir as a model of human lung tissue. Two concentrations (0.1 μM and 1 μM) were tested at three time points (24 hours, 7 days and 28 days). Several aspects were assessed: cytotoxicity (lactate dehydrogenase (LDH) release), integrity of the cell layer (transepithelial electrical resistance (TEER)), induction of oxidative stress (reactive oxygen species production) and changes in the expression of selected genes involved in PAH metabolism ( CYP1A1 and AKR1C2) and the antioxidant response ( ALDH3A1, SOD1, SOD2, GPX1, CAT, HMOX1 and TXNRD1). The results showed that exposure to B[a]P caused a spike in LDH release at day 5. Exposure to 3-NBA caused a number of spikes in LDH release, starting at day 5, and a decrease in TEER after 11 days. CYP1A1 gene expression was upregulated after the 7-day and 28-day B[a]P exposures, as well as after the 24-hour and 7-day 3-NBA exposures. HMOX1 and SOD1 were downregulated after both 24-hour PAH treatments. HMOX1 was upregulated after a 1-week exposure to 3-NBA. There were no significant changes in the messenger RNA (mRNA) levels of AKR1C2, ALDH3A1, TXNRD1, SOD2, GPX1 or CAT. These results illustrate the potential use of this 3-D in vitro lung tissue model in studying the effects of chronic exposure to PAHs.

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