The use of enzymes in organic synthesis and the life sciences: perspectives from the Swiss Industrial Biocatalysis Consortium (SIBC)

2013 ◽  
Vol 3 (1) ◽  
pp. 29-40 ◽  
Author(s):  
Hans-Peter Meyer ◽  
Eric Eichhorn ◽  
Steven Hanlon ◽  
Stephan Lütz ◽  
Martin Schürmann ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Life Sciences ◽  
Enzymes In Organic Synthesis

Enzymes in organic synthesis. 33. Stereoselective pig liver esterase-catalyzed hydrolyses of meso cyclopentyl-, tetrahydrofuranyl-, and tetrahydrothiophenyl-1,3-diesters

1985 ◽  
Vol 63 (2) ◽  
pp. 452-456 ◽  
Author(s):  
J. Bryan Jones ◽  
R. Scott Hinks ◽  
Philip G. Hultin
Keyword(s):  
Organic Synthesis ◽  
Absolute Configuration ◽  
Enantiomeric Excess ◽  
Membered Ring ◽  
Pig Liver ◽  
Pig Liver Esterase ◽  
Preparative Scale ◽  
Liver Esterase ◽  
The Absolute ◽  
Enzymes In Organic Synthesis

Preparative-scale pig liver esterase-catalyzed hydrolyses of five-membered ring meso-1,3-diesters are enantiotopically selective. While pro-S enantiotopic selectivity is exhibited in each case, the absolute configuration sense of the hydrolysis in the cyclopentyl series is opposite to that of both the tetrahydrofuranyl and tetrahydrothiophenyl diesters. The enantiomeric excess levels induced are in the 34–46% range.

Esterolytic and Lipolytic Enzymes in Organic Synthesis

Synthesis ◽  
1991 ◽  
Vol 1991 (12) ◽  
pp. 1049-1072 ◽  
Author(s):  
Wilhelm Boland ◽  
Christian Frößl ◽  
Michael Lorenz
Keyword(s):  
Organic Synthesis ◽  
Lipolytic Enzymes ◽  
Enzymes In Organic Synthesis

ChemInform Abstract: Enzymes in Organic Synthesis: Oxidoreductions.

ChemInform ◽  
2010 ◽  
Vol 26 (33) ◽  
pp. no-no
Author(s):  
J.-M. FANG ◽  
C.-H. LIN ◽  
C. W. BRADSHAW ◽  
C.-H. WONG
Keyword(s):  
Organic Synthesis ◽  
Enzymes In Organic Synthesis

Enzymes in organic synthesis. 32. Stereospecific horse liver alcohol dehydrogenase-catalyzed oxidations of exo- and endo-oxabicyclic meso diols

1984 ◽  
Vol 62 (11) ◽  
pp. 2578-2582 ◽  
Author(s):  
J. Bryan Jones ◽  
Christopher J. Francis
Keyword(s):  
Alcohol Dehydrogenase ◽  
Organic Synthesis ◽  
Horse Liver Alcohol Dehydrogenase ◽  
Preparative Scale ◽  
Enantiomerically Pure ◽  
Liver Alcohol Dehydrogenase ◽  
Horse Liver ◽  
One Step ◽  
Catalyzed Oxidation ◽  
Enzymes In Organic Synthesis

Preparative-scale horse liver alcohol dehydrogenase-catalyzed oxidation of mesoexo- and endo-7-oxabicyclo[2.2.1]heptane diols provides a direct one-step route to enantiomerically pure chiral γ-lactones of the oxabicyclic series.

ChemInform Abstract: Cyclodextrins to Increase the Utility of Enzymes in Organic Synthesis

ChemInform ◽  
2000 ◽  
Vol 31 (47) ◽  
pp. no-no
Author(s):  
J. B. Harper ◽  
C. J. Easton ◽  
S. F. Lincoln
Keyword(s):  
Organic Synthesis ◽  
Enzymes In Organic Synthesis
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