Examining changes in cellular communication in neuroendocrine cells after noble metal nanoparticle exposure

The Analyst ◽  
2012 ◽  
Vol 137 (13) ◽  
pp. 3004 ◽  
Author(s):  
Sara A. Love ◽  
Zhen Liu ◽  
Christy L. Haynes
Keyword(s):  
Noble Metal ◽  
Cellular Communication ◽  
Neuroendocrine Cells ◽  
Metal Nanoparticle ◽  
Nanoparticle Exposure

scholarly journals Current Strategies for Noble Metal Nanoparticle Synthesis

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Giyaullah Habibullah ◽  
Jitka Viktorova ◽  
Tomas Ruml
Keyword(s):  
Noble Metal ◽  
Noble Metals ◽  
Drug Carriers ◽  
Industrial Applications ◽  
Metal Nanoparticle ◽  
Noble Metal Nanoparticles ◽  
Synthesis Methods ◽  
Gold And Silver Nanoparticles ◽  
Diverse Range ◽  
The Past

AbstractNoble metals have played an integral part in human history for centuries; however, their integration with recent advances in nanotechnology and material sciences have provided new research opportunities in both academia and industry, which has resulted in a new array of advanced applications, including medical ones. Noble metal nanoparticles (NMNPs) have been of great importance in the field of biomedicine over the past few decades due to their importance in personalized healthcare and diagnostics. In particular, platinum, gold and silver nanoparticles have achieved the most dominant spot in the list, thanks to a very diverse range of industrial applications, including biomedical ones such as antimicrobial and antiviral agents, diagnostics, drug carriers and imaging probes. In particular, their superior resistance to extreme conditions of corrosion and oxidation is highly appreciated. Notably, in the past two decades there has been a tremendous advancement in the development of new strategies of more cost-effective and robust NMNP synthesis methods that provide materials with highly tunable physicochemical, optical and thermal properties, and biochemical functionalities. As a result, new advanced hybrid NMNPs with polymer, graphene, carbon nanotubes, quantum dots and core–shell systems have been developed with even more enhanced physicochemical characteristics that has led to exceptional diagnostic and therapeutic applications. In this review, we aim to summarize current advances in the synthesis of NMNPs (Au, Ag and Pt).

Tuning optical properties of noble metal nanoparticle-composed glasses by laser radiation

2019 ◽  
Vol 463 ◽  
pp. 968-975 ◽  
Author(s):  
N. Nedyalkov ◽  
M.E. Koleva ◽  
R. Nikov ◽  
N.E. Stankova ◽  
E. Iordanova ◽  
...  
Keyword(s):  
Optical Properties ◽  
Laser Radiation ◽  
Noble Metal ◽  
Metal Nanoparticle

Noble metal nanoparticle-functionalized Zr-metal organic frameworks with excellent photocatalytic performance

2019 ◽  
Vol 538 ◽  
pp. 569-577 ◽  
Author(s):  
Jianhao Qiu ◽  
Xingguang Zhang ◽  
Kailuo Xie ◽  
Xiong-Fei Zhang ◽  
Yi Feng ◽  
...  
Keyword(s):  
Noble Metal ◽  
Photocatalytic Performance ◽  
Metal Organic Frameworks ◽  
Metal Nanoparticle ◽  
Metal Organic

scholarly journals Enhanced inhibition of influenza virus infection by peptide–noble-metal nanoparticle conjugates

2019 ◽  
Vol 10 ◽  
pp. 1038-1047 ◽  
Author(s):  
Zaid K Alghrair ◽  
David G Fernig ◽  
Bahram Ebrahimi
Keyword(s):  
Silver Nanoparticles ◽  
Influenza Virus ◽  
Antiviral Activity ◽  
Noble Metal ◽  
Metal Nanoparticle ◽  
Model Systems ◽  
Health Concern ◽  
Virus Infectivity ◽  
Mixed Matrix ◽  
Gold And Silver Nanoparticles

The influenza (“flu”) type-A virus is a major medical and veterinary health concern and causes global pandemics. The peptide “FluPep” is an established inhibitor of influenza virus infectivity in model systems. We have explored the potential for noble-metal nanoparticle conjugates of FluPep to enhance its antiviral activity and to determine their potential as a delivery platform for FluPep. FluPep ligand is FluPep extended at its N-terminus with the sequence CVVVTAAA, to allow for its incorporation into a mixed-matrix ligand shell of a peptidol and an alkanethiol ethylene glycol consisting of 70% CVVVTol and 30% HS(CH2)11(OC2H4)4OH (mol/mol). Gold and silver nanoparticles (ca. 10 nm diameter) with up to 5% (mol/mol) FluPep ligand remained as stable as the control of mixed-matrix-passivated nanoparticles in a variety of tests, including ligand exchange with dithiothreitol. The free FluPep ligand peptide was found to inhibit viral plaque formation in canine MDCK cells (IC50 = 2.1 nM), but was less potent than FluPep itself (IC50 = 140 pM). Nanoparticles functionalised with FluPep ligand showed enhanced antiviral activity compared to the free peptides. The IC50 value of the FluPep-functionalised nanoparticles decreased as the grafting density of FluPep ligand increased from 0.03% to 5% (both mol/mol), with IC50 values down to about 10% of that of the corresponding free peptide. The data demonstrate that conjugation of FluPep to gold and silver nanoparticles enhances its antiviral potency; the antimicrobial activity of silver ions may enable the design of even more potent antimicrobial inhibitors, capable of targeting both influenza and bacterial co-infections.

Noble metal nanoparticle-decorated TiO2 nanobelts for enhanced photocatalysis

2014 ◽  
Vol 07 (05) ◽  
pp. 1450064 ◽  
Author(s):  
Haiyan He ◽  
Ping Yang ◽  
Changchao Jia ◽  
Yanping Miao ◽  
Jie Zhao ◽  
...  
Keyword(s):  
Noble Metal ◽  
Au Nanoparticles ◽  
Acid Corrosion ◽  
Metal Nanoparticle ◽  
Noble Metal Nanoparticles ◽  
Au Nanoparticle ◽  
Chloroauric Acid ◽  
Sem Images ◽  
Photogenerated Electrons ◽  
Coarse Surface

TiO 2 nanobelts have been fabricated through a hydrothermal method and subsequently sulfuric-acid-corrosion-treated for a rough surface. Noble metal nanoparticles such as Ag and Au were deposited on the coarse surface of TiO 2 nanobelts via a coprecipitation procedure. Ag – TiO 2 nanobelts were prepared in ethanolic solution contained silver nitrate ( AgNO 3) and sodium hydroxide ( NaOH ). Au – TiO 2 nanobelts were obtained in chloroauric acid ( HAuCl 4) using sodium borohydride ( NaBH 4) as the reductant. It is confirmed by the results of XRD patterns together with the SEM images that the composite of noble metal and TiO 2 nanobelts were obtained successfully and the Ag or Au nanoparticles were well-dispersed on the TiO 2 nanobelts. Moreover, the as-prepared Ag and Au nanoparticle-decorated TiO 2 nanobelts represent an enhanced photocatalytic activity compared with pure TiO 2 nanobelts, which is due to the fact that the Ag and Au nanoparticles on the surface of TiO 2 nanobelts act as sinks for the photogenerated electrons and promote the separation of the electrons and holes.

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