4,17a-Diaza-D-homoandrostane lactams, a new hetero-steroid system

1970 ◽  
pp. 522a ◽  
Author(s):  
Harkishan Singh ◽  
Veerendra V. Parashar
Keyword(s):  
Steroid System

Mass spectrometry of steroid system—IX

Tetrahedron ◽  
1967 ◽  
Vol 23 (9) ◽  
pp. 3667-3682 ◽  
Author(s):  
N.S. Wulfson ◽  
V.I. Zaretskii ◽  
V.L. Sadovskaya ◽  
A.V. Zakharychev ◽  
S.N. Ananchenko ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Steroid System

ChemInform Abstract: First Example of Construction of a Pyrrole Ring Bonded to a Steroid System by the Trofimov Reaction.

ChemInform ◽  
2010 ◽  
Vol 33 (38) ◽  
pp. no-no
Author(s):  
A. M. Vasil'tsov ◽  
E. Yu. Shmidt ◽  
A. I. Mikhaleva ◽  
A. V. Afonin ◽  
A. B. Zaitsev
Keyword(s):  
Pyrrole Ring ◽  
Trofimov Reaction ◽  
Steroid System

Steroids. CXCI.1Some Reactions of a 6-Methyl-▵5-3β-hydroxy Steroid System

1962 ◽  
Vol 27 (4) ◽  
pp. 1139-1148 ◽  
Author(s):  
J. IRIARTE ◽  
J. N. SHOOLERY ◽  
CARL DJERASSI
Keyword(s):  
Steroid System ◽  
Hydroxy Steroid

Role of cardiac steroid system in heart failure

2008 ◽  
Vol 14 (7) ◽  
pp. S142
Author(s):  
Kazuhiro Yamamoto ◽  
Toshiaki Mano ◽  
Tomohito Ohtani ◽  
Yasuharu Takeda ◽  
Yasushi Sakata
Keyword(s):  
Heart Failure ◽  
Steroid System

Synthesis and X-ray structure of the 8,13-diaza-steroid system

1968 ◽  
pp. 1274 ◽  
Author(s):  
J. H. Burckhalter ◽  
Hanley N. Abramson ◽  
John G. MacConnell ◽  
Ronald J. Thill ◽  
Arthur J. Olson ◽  
...  
Keyword(s):  
X Ray ◽  
Steroid System

scholarly journals Steroid Hormone Sensitivity in Reproductive Mood Disorders: On the Role of the GABAA Receptor Complex and Stress During Hormonal Transitions

2021 ◽  
Vol 7 ◽  
Author(s):  
Sophie Schweizer-Schubert ◽  
Jennifer L. Gordon ◽  
Tory A. Eisenlohr-Moul ◽  
Samantha Meltzer-Brody ◽  
Katja M. Schmalenberger ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Mood Disorders ◽  
Psychosocial Factors ◽  
Psychological Treatment ◽  
Steroid Hormone ◽  
Receptor Complex ◽  
Hormone Sensitivity ◽  
Steroid System ◽  
Steroid Hormone Sensitivity

Women worldwide are two to three times more likely to suffer from depression in their lifetime than are men. Female risk for depressive symptoms is particularly high during the reproductive years between menarche and menopause. The term “Reproductive Mood Disorders” refers to depressive disorders triggered by hormonal fluctuations during reproductive transitions including the perimenarchal phase, the pre-menstrual phase, pregnancy, the peripartum period and the perimenopausal transition.Here we focus on reproductive mood disorders manifesting in adult life. We propose a research agenda that draws together several reproductive mood disorders and investigates which genetic, endocrinological, neural, and psychosocial factors can explain depressive symptoms during phases of hormonal transitions in women. Based on current research it is assumed that some women experience an increased sensitivity to not only fluctuations in reproductive steroids (estrogen and progesterone), but also stress-related steroids. We integrate both dynamics into the concept of “steroid hormone sensitivity,” expanding on the concept of “reproductive hormone sensitivity.” We suggest that a differential response of the stress steroid system including corticosteroids, neurosteroids, like allopregnanolone and the GABA-A Receptor complex, as well as a differential (epi)genetic risk in serotonergic and GABAergic signaling, are moderators or mediators between changes in the reproductive steroid system and the physiological, affective, and cognitive outcomes manifesting in reproductive mood disorders. We point to the lack of research on the role of psychosocial factors in increasing a woman's stress level and at some point also the sensitivity of her stress steroid system within the etiology of Reproductive Mood Disorders.Drawing together the evidence on various reproductive mood disorders we seek to present a basis for the development of more effective pharmacological, social, and psychological treatment interventions and prevention strategies for women susceptible to these disorders. This could pave the way for new research as well as medical and psychological teaching and practice- such as a new type of Practice for Gynecological Psychoneuroendocrinology- with the aim of working on and ultimately offering more integrative forms of support not yet available to women suffering from depression during hormonal transitions. In medical history women have been left alone with this integrative challenge.

Sign in / Sign up

Export Citation Format

Share Document