Hierarchical self-assembly and secondary structures of linear polypeptides graft onto POSS in the side chain through click chemistry

2012 ◽  
Vol 3 (1) ◽  
pp. 162-171 ◽  
Author(s):  
Yung-Chih Lin ◽  
Shiao-Wei Kuo
Keyword(s):  
Click Chemistry ◽  
Self Assembly ◽  
Secondary Structures ◽  
Side Chain

Synthesis and self-assembly behaviours of side-chain smectic thiol–ene polymers based on the polysiloxane backbone

2016 ◽  
Vol 4 (7) ◽  
pp. 1425-1440 ◽  
Author(s):  
Wenhuan Yao ◽  
Yanzi Gao ◽  
Xiao Yuan ◽  
Baofeng He ◽  
Haifeng Yu ◽  
...  
Keyword(s):  
Liquid Crystal ◽  
Click Chemistry ◽  
Self Assembly ◽  
Side Chain ◽  
Liquid Crystal Polymers ◽  
Different Types

A series of novel chiral polysiloxane side chain liquid crystal polymers (PSCLCPs) with two different types of LC phases and three self-assembly arrangements were successfully synthesized via thiol–ene click chemistry.

Synthesis and self-assembly of thermotropic block copolymer with long alkyl tethered cage silsesquioxane in the side chain

2011 ◽  
Vol 49 (12) ◽  
pp. 2653-2664 ◽  
Author(s):  
Yoshihito Ishida ◽  
Tomoyasu Hirai ◽  
Raita Goseki ◽  
Masatoshi Tokita ◽  
Masa-Aki Kakimoto ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Self Assembly ◽  
Side Chain

Synthesis of a Cholesterol Side-Chain Triazole Analogue via ‘Click’ Chemistry

Synthesis ◽  
2015 ◽  
Vol 47 (18) ◽  
pp. 2826-2830 ◽  
Author(s):  
Matar Seck ◽  
Yagamare Fall ◽  
Insa Seck ◽  
Alioune Fall ◽  
Carmen Lago ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Side Chain

Copper-free click chemistry on polymersomes: pre- vs. post-self-assembly functionalisation

2012 ◽  
Vol 3 (7) ◽  
pp. 1783-1795 ◽  
Author(s):  
Silvie A. Meeuwissen ◽  
Marjoke F. Debets ◽  
Jan C. M. van Hest
Keyword(s):  
Click Chemistry ◽  
Self Assembly

Synthesis and self-assembly of side-chain azocomplex for preparation of solid and hollow nanosphere

2012 ◽  
Vol 290 (8) ◽  
pp. 741-749 ◽  
Author(s):  
Cheng Jin ◽  
Yongchao Zhao ◽  
Huixia Wang ◽  
Kunhua Lin ◽  
Qinjian Yin
Keyword(s):  
Self Assembly ◽  
Side Chain ◽  
Hollow Nanosphere

Click Synthesis of Shape-Persistent Azodendrimers and their Orthogonal Self-Assembly to Nanofibres

2018 ◽  
Vol 71 (6) ◽  
pp. 463 ◽  
Author(s):  
Tamer El Malah ◽  
Hany F. Nour
Keyword(s):  
Electron Microscopy ◽  
Mass Spectrometry ◽  
Self Assembly ◽  
Molecular Structures ◽  
Side Chain ◽  
Spectroscopic Techniques ◽  
Molecular Weights ◽  
Transmission Electron ◽  
Click Synthesis ◽  
Scanning Electron

The copper(i)-catalyzed azide–alkyne cycloaddition (CuAAC) reaction has been efficiently utilized to synthesize a series of dendrons with amino functionalities. The aminodendrons successfully underwent azodimerization to furnish a series of pyridyl- and phenyl-based azodendrimers with peripheral alkyl or ether side chain substituents. The molecular structures of the azodendrimers were fully assigned using different spectroscopic techniques, such as 1H NMR and 13C NMR, and the molecular weights were determined using MALDI-TOF mass spectrometry. The molecular self-assembly of the azodendrimers was investigated by scanning electron microscopy and transmission electron microscopy, which revealed the formation of highly ordered and uniform self-assembled nanofibres.

scholarly journals pH- and concentration-dependent supramolecular self-assembly of a naturally occurring octapeptide

2020 ◽  
Vol 16 ◽  
pp. 2017-2025
Author(s):  
Goutam Ghosh ◽  
Gustavo Fernández
Keyword(s):  
Self Assembly ◽  
Ph Value ◽  
Secondary Structures ◽  
Random Coil ◽  
Conformational Transformation ◽  
Stimuli Responsive ◽  
Responsive Materials ◽  
Force Microscopy ◽  
Assembly Behavior ◽  
Novel Drug

Peptide-based biopolymers represent highly promising biocompatible materials with multiple applications, such as tailored drug delivery, tissue engineering and regeneration, and as stimuli-responsive materials. Herein, we report the pH- and concentration-dependent self-assembly and conformational transformation of the newly synthesized octapeptide PEP-1. At pH 7.4, PEP-1 forms β-sheet-rich secondary structures into fractal-like morphologies, as verified by circular dichroism (CD), Fourier-transform infrared (FTIR) spectroscopy, thioflavin T (ThT) fluorescence spectroscopy assay, and atomic force microscopy (AFM). Upon changing the pH value (using pH 5.5 and 13.0), PEP-1 forms different types of secondary structures and resulting morphologies due to electrostatic repulsion between charged amino acids. PEP-1 can also form helical or random-coil secondary structures at a relatively low concentration. The obtained pH-sensitive self-assembly behavior of the target octapeptide is expected to contribute to the development of novel drug nanocarrier assemblies.

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