Modulation of gene expression by the oxidative stress generated in human skin cells by UVA radiation and the restoration of redox homeostasis

2012 ◽  
Vol 11 (1) ◽  
pp. 135-147 ◽  
Author(s):  
Rex M. Tyrrell
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Human Skin ◽  
Redox Homeostasis ◽  
Skin Cells ◽  
Modulation Of Gene Expression ◽  
Human Skin Cells ◽  
Uva Radiation

scholarly journals Proteins of the Extracellular Matrix Are Sensitizers of Photo-oxidative Stress in Human Skin Cells

2003 ◽  
Vol 121 (3) ◽  
pp. 578-586 ◽  
Author(s):  
Georg T. Wondrak ◽  
Michael J. Roberts ◽  
Daniel Cervantes-Laurean ◽  
Myron K. Jacobson ◽  
Elaine L. Jacobson
Keyword(s):  
Oxidative Stress ◽  
Extracellular Matrix ◽  
Human Skin ◽  
Skin Cells ◽  
Human Skin Cells

Effect of UVA radiation on the Nrf2 signalling pathway in human skin cells

2020 ◽  
Vol 209 ◽  
pp. 111948
Author(s):  
Alena Ryšavá ◽  
Kateřina Čížková ◽  
Jana Franková ◽  
Lenka Roubalová ◽  
Jitka Ulrichová ◽  
...  
Keyword(s):  
Human Skin ◽  
Signalling Pathway ◽  
Skin Cells ◽  
Human Skin Cells ◽  
Uva Radiation

MON-LB674: Dracocephalum Moldavica L. Seed Extracts Modulate Inflammation and Oxidative Stress in Human Skin Cells

2019 ◽  
Vol 38 ◽  
pp. S310
Author(s):  
E. Song ◽  
J. Choi ◽  
H. Gwon ◽  
S.-G. Choi ◽  
J. Chun ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Human Skin ◽  
Skin Cells ◽  
Human Skin Cells ◽  
And Oxidative Stress ◽  
Seed Extracts

scholarly journals Can Light Emitted from Smartphone Screens and Taking Selfies Cause Premature Aging and Wrinkles?

2018 ◽  
Vol 8 (4Dec) ◽  
Author(s):  
N Arjmandi ◽  
Gh Mortazavi ◽  
S Zarei ◽  
M Faraz ◽  
S A R Mortazavi
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Visible Light ◽  
Human Skin ◽  
Blue Light ◽  
Biological Effects ◽  
Premature Aging ◽  
Oxygen Species ◽  
Skin Cells ◽  
Human Skin Cells

Since the early days of human life on the Earth, our skin has been exposed to different levels of light. Recently, due to inevitable consequences of modern life, humans are not exposed to adequate levels of natural light during the day but they are overexposed to relatively high levels of artificial light at night. Skin is a major target of oxidative stress and the link between aging and oxidative stress is well documented. Especially, extrinsic skin aging can be caused by oxidative stress. The widespread use of light emitting diodes (LEDs) and the rapidly increasing use of smartphones, tablets, laptops and desktop computers have led to a significant rise in the exposure of human eyes to short-wavelength visible light. Recent studies show that exposure of human skin cells to light emitted from electronic devices, even for exposures as short as 1 hour, may cause reactive oxygen species (ROS) generation, apoptosis, and necrosis. The biological effects of exposure to short-wavelength visible light in blue region in humans and other living organisms were among our research priorities at the Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC). Today, there is a growing concern over the safety of the light sources such as LEDs with peak emissions in the blue light range (400-490 nm). Recent studies aimed at investigating the effect of exposure to light emitted from electronic device on human skin cells, shows that even short exposures can increase the generation of reactive oxygen species. However, the biological effects of either long-term or repeated exposures are not fully known, yet. Furthermore, there are reports indicating that frequent exposure to visible light spectrum of the selfie flashes may cause skin damage and accelerated skin ageing. In this paper we have addressed the different aspects of potential effects of exposure to the light emitted from smartphones’ digital screens as well as smartphones’ photoflashes on premature aging of the human skin. Specifically, the effects of blue light on eyes and skin are discussed. Based on current knowledge, it can be suggested that changing the spectral output of LED-based smartphones’ flashes can be introduced as an effective method to reduce the adverse health effects associated with exposure to blue light.

scholarly journals Antioxidant and Cellular Protective Effects against Oxidative Stress of Calendula officinalis Flowers Extracts in Human Skin Cells

2016 ◽  
Vol 27 (6) ◽  
pp. 620-626 ◽  
Author(s):  
Song Hua Xuan ◽  
Ga Yoon Kim ◽  
Ji Yeon Yu ◽  
Jee Won Kim ◽  
Ye Rim Yang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Human Skin ◽  
Protective Effects ◽  
Calendula Officinalis ◽  
Skin Cells ◽  
Human Skin Cells
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