Improvement of in vitro-transcribed amber suppressor tRNAs toward higher suppression efficiency in wheat germ extract

2011 ◽  
Vol 9 (24) ◽  
pp. 8495 ◽  
Author(s):  
Atsushi Ogawa ◽  
Yasunori Doi ◽  
Nobuto Matsushita
Keyword(s):  
Wheat Germ ◽  
Wheat Germ Extract ◽  
Suppression Efficiency ◽  
Amber Suppressor

scholarly journals Decrease in the Rate of Protein Synthesis by Polysomes from Cultured Fibroblasts of Patients and Carriers with Duchenne Muscular Dystrophy

1979 ◽  
Vol 6 (3) ◽  
pp. 355-358 ◽  
Author(s):  
M. Boulé ◽  
M. Vanasse ◽  
L. Brakier-Gingras
Keyword(s):  
Protein Synthesis ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Wheat Germ ◽  
Fibroblast Cells ◽  
Wheat Germ Extract ◽  
Cultured Fibroblasts ◽  
Normal Controls

SUMMARY:Polysomes extracted from cultured fibroblast cells isolated from patients with Duchenne muscular dystrophy (DMD), carriers of the disease, and normal controls were used for in vitro measurement of protein synthesis in a wheat germ extract system. It was observed that polysomes from patients and carriers (seven of each aged 17 years or older) exhibited a 3-fold and a 1.5-fold decrease in the rate of protein synthesis, respectively, as compared with controls. These results are discussed with a view to developing a sensitive and easily available assay for the detection of DMD carriers.

Investigation of end processing and degradation of premature tRNAs and their application to stabilization of in vitro transcripts in wheat germ extract

2015 ◽  
Vol 13 (4) ◽  
pp. 1008-1012 ◽  
Author(s):  
Atsushi Ogawa ◽  
Yasunori Doi
Keyword(s):  
Wheat Germ ◽  
Wheat Germ Extract ◽  
In Vitro Transcripts

We investigated the end processing and degradation of premature tRNAs in wheat germ extract (left), which led to the findings of end protectors for efficiently stabilizing an in vitro transcript (purple, right).

scholarly journals The Effects of Adjuvant Fermented Wheat Germ Extract on Cancer Cell Lines: A Systematic Review

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1546 ◽  
Author(s):  
Khrystyna Zhurakivska ◽  
Giuseppe Troiano ◽  
Vito Caponio ◽  
Mario Dioguardi ◽  
Claudia Arena ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cell Lines ◽  
Cancer Cell ◽  
Wheat Germ ◽  
Cancer Cell Lines ◽  
In Vivo Studies ◽  
Wheat Germ Extract ◽  
Fermented Wheat Germ Extract

Fermented wheat germ extract (FWGE; trade name AVEMAR) is a natural compound derived from industrial fermentation of wheat germ. Its potential anticancer properties has emerged from recent studies. The aim of this systematic review is to summarize the data available in the scientific literature concerning the in vitro activity of FWGE on malignant cells. A systematic review of English articles in electronic databases has been performed. The primary outcomes of the review regarded types of cancer cell lines subjected to the investigation and the main results concerning cell viability, proliferation, and apoptosis observed within the studies. Sixteen articles were included in the final qualitative analysis. Various types of cancer cells treated with FWGE have been analyzed, showing mainly cytotoxic effects, alteration of the cell cycle, antiproliferative effects, and induction of apoptosis. FWGE can be a promising drug component in cancer treatment; however, further in vitro and in vivo studies are necessary to prove its effectiveness and safety in humans.

Effects of Fermented Wheat Germ Extract on Oral Cancer Cells: An In Vitro Study

2021 ◽  
pp. 1-9
Author(s):  
Khrystyna Zhurakivska ◽  
Maija Risteli ◽  
Tuula Salo ◽  
Davide Sartini ◽  
Alessia Salvucci ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Cells ◽  
Wheat Germ ◽  
In Vitro Study ◽  
Vitro Study ◽  
Wheat Germ Extract ◽  
Oral Cancer Cells ◽  
Fermented Wheat Germ Extract
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