Theoretical investigation on mechanism of asymmetric Michael addition of malononitrile to chalcones catalyzed by Cinchona alkaloid aluminium(iii) complex

2011 ◽  
Vol 9 (18) ◽  
pp. 6402 ◽  
Author(s):  
Zhishan Su ◽  
Hai Whang Lee ◽  
Chan Kyung Kim
Keyword(s):  
Theoretical Investigation ◽  
Michael Addition ◽  
Cinchona Alkaloid ◽  
Asymmetric Michael Addition

Recyclable cinchona alkaloid catalyzed asymmetric Michael addition reaction

2013 ◽  
Vol 54 (45) ◽  
pp. 6064-6066 ◽  
Author(s):  
Xin Huang ◽  
Wen-Bin Yi ◽  
Danash Ahad ◽  
Wei Zhang
Keyword(s):  
Michael Addition ◽  
Addition Reaction ◽  
Cinchona Alkaloid ◽  
Michael Addition Reaction ◽  
Asymmetric Michael Addition

scholarly journals Novel Selenoureas Based on Cinchona Alkaloid Skeleton: Synthesis and Catalytic Investigations

Materials ◽  
2021 ◽  
Vol 14 (3) ◽  
pp. 600
Author(s):  
Mariola Zielińska-Błajet ◽  
Joanna Najdek
Keyword(s):  
Michael Addition ◽  
Catalytic Performance ◽  
Cinchona Alkaloid ◽  
Addition Reactions ◽  
Efficient Approach ◽  
Mild Conditions ◽  
Asymmetric Michael Addition

An efficient approach to the synthesis of chiral selenoureas consisting of Cinchona alkaloid scaffolds was described. The new selenoureas were assessed as bifunctional organocatalysts in the asymmetric Michael addition reactions under mild conditions. The best results were obtained for selenoureas bearing the 4-fluorophenyl group. These catalysts promoted the reactions with enantioselectivities of up to 96% ee. Additionally, the catalytic performance of the thiourea and selenourea counterpart was compared.

Squaramide−catalysed asymmetric Michael addition/cyclization cascade reactions of 4-arylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones

2021 ◽  
Author(s):  
Xiqiang Hou ◽  
Jiang-Bo Wen ◽  
Li Yan ◽  
Da-Ming Du
Keyword(s):  
Michael Addition ◽  
Cascade Reactions ◽  
Cascade Reaction ◽  
Cinchona Alkaloid ◽  
Highly Efficient ◽  
Asymmetric Michael Addition

A highly efficient cinchona alkaloid‐derived squaramide catalysed asymmetric Michael/cyclization cascade reaction of 4‐ arylmethylidene‐2,3‐dioxopyrrolidines with 2‐isothiocyanato‐1‐indanones was successfully developed. This protocol provides an efficient and mild access to obtain indanone‐derived...

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