Pyrrolidinyl-sulfamide derivatives as a new class of bifunctional organocatalysts for direct asymmetric Michael addition of cyclohexanone to nitroalkenes

2011 ◽  
Vol 9 (14) ◽  
pp. 5280 ◽  
Author(s):  
Jia-Rong Chen ◽  
Liang Fu ◽  
You-Quan Zou ◽  
Ning-Jie Chang ◽  
Jian Rong ◽  
...  
Keyword(s):  
Michael Addition ◽  
New Class ◽  
Asymmetric Michael Addition

Pyrrolidinyl-Camphor Derivatives as a New Class of Organocatalyst for Direct Asymmetric Michael Addition of Aldehydes and Ketones to β-Nitroalkenes

2010 ◽  
Vol 16 (23) ◽  
pp. 7030-7038 ◽  
Author(s):  
Ying-Fang Ting ◽  
Chihliang Chang ◽  
Raju Jannapu Reddy ◽  
Dhananjay R. Magar ◽  
Kwunmin Chen
Keyword(s):  
Michael Addition ◽  
New Class ◽  
Asymmetric Michael Addition ◽  
Aldehydes And Ketones ◽  
Camphor Derivatives

scholarly journals 3,3′-Bimorpholine Derivatives as a New Class of Organocatalysts for Asymmetric Michael Addition.

ChemInform ◽  
2006 ◽  
Vol 37 (43) ◽  
Author(s):  
Sarah Mosse ◽  
Marju Laars ◽  
Kadri Kriis ◽  
Tonis Kanger ◽  
Alexandre Alexakis
Keyword(s):  
Michael Addition ◽  
New Class ◽  
Asymmetric Michael Addition

ChemInform Abstract: Pyrrolidinyl-Sulfamide Derivatives as a New Class of Bifunctional Organocatalysts for Direct Asymmetric Michael Addition of Cyclohexanone to Nitroalkenes.

ChemInform ◽  
2011 ◽  
Vol 42 (49) ◽  
pp. no-no
Author(s):  
Jia-Rong Chen ◽  
Liang Fu ◽  
You-Quan Zou ◽  
Ning-Jie Chang ◽  
Jian Rong ◽  
...  
Keyword(s):  
Michael Addition ◽  
New Class ◽  
Asymmetric Michael Addition

3,3‘-Bimorpholine Derivatives as a New Class of Organocatalysts for Asymmetric Michael Addition

2006 ◽  
Vol 8 (12) ◽  
pp. 2559-2562 ◽  
Author(s):  
Sarah Mossé ◽  
Marju Laars ◽  
Kadri Kriis ◽  
Tõnis Kanger ◽  
Alexandre Alexakis
Keyword(s):  
Michael Addition ◽  
New Class ◽  
Asymmetric Michael Addition

A new class of chiral pyrrolidine for asymmetric Michael addition reactions. New mechanism via simple 4+2 type attack of the enamine on the trans-nitrostyrene

Tetrahedron ◽  
2007 ◽  
Vol 63 (3) ◽  
pp. 740-747 ◽  
Author(s):  
David Diez ◽  
M. Jose Gil ◽  
Rosalina F. Moro ◽  
Isidro S. Marcos ◽  
P. García ◽  
...  
Keyword(s):  
Michael Addition ◽  
Addition Reactions ◽  
New Class ◽  
Asymmetric Michael Addition

scholarly journals Facile and Promising Method for Michael Addition of Indole and Pyrrole to Electron-Deficienttrans-β-Nitroolefins Catalyzed by a Hydrogen Bond Donor Catalyst Feist’s Acid and Preliminary Study of Antimicrobial Activity

2014 ◽  
Vol 2014 ◽  
pp. 1-15 ◽  
Author(s):  
Abdullah M. A. Al Majid ◽  
Mohammad Shahidul Islam ◽  
Assem Barakat ◽  
Mohamed H. M. Al-Agamy ◽  
Mu. Naushad
Keyword(s):  
Antimicrobial Activity ◽  
Hydrogen Bond ◽  
Michael Addition ◽  
Hydrogen Bond Donor ◽  
New Class ◽  
Optimum Reaction ◽  
Preliminary Study ◽  
Cooperative Hydrogen Bonding ◽  
The Michael Addition

The importance of cooperative hydrogen-bonding effects has been demonstrated using novel 3-methylenecyclopropane-1,2-dicarboxylic acid (Feist’s acid (FA)) as hydrogen bond donor catalysts for the addition of indole and pyrrole totrans-β-nitrostyrene derivatives. Because of the hydrogen bond donor (HBD) ability, Feist’s acid (FA) has been introduced as a new class of hydrogen bond donor catalysts for the activation of nitroolefin towards nucleophilic substitution reaction. It has effectively catalyzed the Michael addition of indoles and pyrrole toβ-nitroolefins under optimum reaction condition to furnish the corresponding Michael adducts in good to excellent yields (up to 98%). The method is general, atom-economical, convenient, and eco-friendly and could provide excellent yields and regioselectivities. Some newly synthesized compounds were for examinedin vitroantimicrobial activity and their preliminary results are reported.

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