Surface modified superparamagnetic iron oxide nanoparticles (SPIONs) for high efficiency folate-receptor targeting with low uptake by macrophages

2011 ◽  
Vol 21 (40) ◽  
pp. 16094 ◽  
Author(s):  
Chao Huang ◽  
Koon Gee Neoh ◽  
En-Tang Kang ◽  
Borys Shuter
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
High Efficiency ◽  
Folate Receptor ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Receptor Targeting ◽  
Folate Receptor Targeting ◽  
Surface Modified

Evaluation of Surface-modified Superparamagnetic Iron Oxide Nanoparticles to Optimize Bacterial Immobilization for Bio-separation with the Least Inhibitory Effect on Microorganism Activity

2020 ◽  
Vol 10 (2) ◽  
pp. 166-174
Author(s):  
Mehdi Khoshneviszadeh ◽  
Sarah Zargarnezhad ◽  
Younes Ghasemi ◽  
Ahmad Gholami
Keyword(s):  
Iron Oxide ◽  
Amino Acid ◽  
Magnetic Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Surface Coating ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Surface Charges ◽  
Surface Modified

Background: Magnetic cell immobilization has been introduced as a novel, facile and highly efficient approach for cell separation. A stable attachment between bacterial cell wall with superparamagnetic iron oxide nanoparticles (SPIONs) would enable the microorganisms to be affected by an outer magnetic field. At high concentrations, SPIONs produce reactive oxygen species in cytoplasm, which induce apoptosis or necrosis in microorganisms. Choosing a proper surface coating could cover the defects and increase the efficiency. Methods: In this study, asparagine, APTES, lipo-amino acid and PEG surface modified SPIONs was synthesized by co-precipitation method and characterized by FTIR, TEM, VSM, XRD, DLS techniques. Then, their protective effects against four Gram-positive and Gram-negative bacterial strains including Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were examined through microdilution broth and compared to naked SPION. Results: The evaluation of characterization results showed that functionalization of magnetic nanoparticles could change their MS value, size and surface charges. Also, the microbial analysis revealed that lipo-amino acid coated magnetic nanoparticles has the least adverse effect on microbial strain among tested SPIONs. Conclusion: This study showed lipo-amino acid could be considered as the most protective and even promotive surface coating, which is explained by its optimizing effect on cell penetration and negligible reductive effects on magnetic properties of SPIONs. lipo-amino acid coated magnetic nanoparticles could be used in microbial biotechnology and industrial microbiology.

Effect of surface-modified superparamagnetic iron oxide nanoparticles (SPIONS) on mast cell infiltration: An acute in vivo study

2016 ◽  
Vol 12 (6) ◽  
pp. 1523-1533 ◽  
Author(s):  
Arumugam Sabareeswaran ◽  
Ereath Beeran Ansar ◽  
Parimanathu Rama Varma Harikrishna Varma ◽  
Parayanthala Vilappil Mohanan ◽  
Thrikkovil Variathu Kumary
Keyword(s):  
Mast Cell ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Cell Infiltration ◽  
Oxide Nanoparticles ◽  
Surface Modified ◽  
Effect Of Surface

scholarly journals Superparamagnetic iron oxide nanoparticles (SPIONs) conjugated with lipase Candida antarctica A for biodiesel synthesis

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38490-38496
Author(s):  
Luis Fernando Peffi Ferreira ◽  
Thayná Mazzi de Oliveira ◽  
Sergio Hiroshi Toma ◽  
Marcos Makoto Toyama ◽  
Koiti Araki ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Enzymatic Activity ◽  
Iron Oxide Nanoparticles ◽  
High Efficiency ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Biodiesel Production ◽  
Oxide Nanoparticles ◽  
Biodiesel Synthesis ◽  
Lipase A

A newly designed biocatalyst prepared by conjugation of lipase A on SPION demonstrated high efficiency for biodiesel production. The nanomaterial was characterized by FTIR, TGA and XRD, and its enzymatic activity compared with a commercial standard.

An In-Situ Functionalization of Decanethiol Monolayer on Thin Silica Coated Superparamagnetic Iron Oxide Nanoparticles Synthesized by Non-Seeded Process

2014 ◽  
Vol 1024 ◽  
pp. 300-303 ◽  
Author(s):  
Sodipo Bashiru Kayode ◽  
Azlan Abdul Aziz
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Silanol Group ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Composite Nanoparticles ◽  
Oxide Nanoparticles ◽  
Magnetic Composite ◽  
Surface Modified

Superparamagnetic iron oxide nanoparticles (SPION) are routinely employed in biomedical and water treatment applications due to their inherent magnetic properties. However, for these applications a surface modified and functionalized SPION is required. Herein, for the first time we present an in-situ method of functionalizing decanethiol monolayer on thin silica coated SPION synthesised via a non-seeded process. Through physico-chemical analyses the grafting of decanethiol onto the composite nanoparticles were demonstrated. The alkane functional group in the monolayer molecule attached to the silanol group of the silica shell and became the tail and binding site to the magnetic composite nanoparticles.

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