scholarly journals Manganite perovskite nanoparticles for self-controlled magnetic fluid hyperthermia: about the suitability of an aqueous combustion synthesis route

2011 ◽  
Vol 21 (12) ◽  
pp. 4393 ◽  
Author(s):  
Romain Epherre ◽  
Etienne Duguet ◽  
Stéphane Mornet ◽  
Emil Pollert ◽  
Stéphanie Louguet ◽  
...  
Keyword(s):  
Combustion Synthesis ◽  
Magnetic Fluid ◽  
Magnetic Fluid Hyperthermia ◽  
Synthesis Route ◽  
Manganite Perovskite ◽  
Perovskite Nanoparticles

New insights into the heating mechanisms and self-regulating abilities of manganite perovskite nanoparticles suitable for magnetic fluid hyperthermia

Nanoscale ◽  
2012 ◽  
Vol 4 (13) ◽  
pp. 3954 ◽  
Author(s):  
Eva Natividad ◽  
Miguel Castro ◽  
Graziella Goglio ◽  
Irene Andreu ◽  
Romain Epherre ◽  
...  
Keyword(s):  
Magnetic Fluid ◽  
Magnetic Fluid Hyperthermia ◽  
Manganite Perovskite ◽  
Perovskite Nanoparticles

scholarly journals Magnetic Fluid Hyperthermia of Rodent Tumors Using Manganese Perovskite Nanoparticles

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Larissa Bubnovskaya ◽  
Anatolij Belous ◽  
Sergej Solopan ◽  
Antonina Kovelskaya ◽  
Lyudmila Bovkun ◽  
...  
Keyword(s):  
Magnetic Fluid ◽  
Tumor Growth Inhibition ◽  
Complete Regression ◽  
Lanthanum Strontium Manganite ◽  
Magnetic Fluid Hyperthermia ◽  
Lanthanum Strontium ◽  
Manganite Nanoparticles ◽  
Thermal Enhancement ◽  
Perovskite Nanoparticles

Purpose. To test the antitumor activity of magnetic fluid (MF) on the basis of substituted lanthanum-strontium manganite nanoparticles combined with alternating magnetic field (AMF) in experiments with transplanted tumors. Materials and Methods. MF with a size of nanoparticles of 30–40 nm in aqueous agarose solution was investigated. The ability of MF to heat tumor under AMF (300 kHz, 7.7 kA/m) was tested in vivo with rodent tumors (Guerin carcinoma, Walker-256 carcinosarcoma, and Lewis lung carcinoma (3LL)). Results. Single administration of MF into the tumor at a dose of 150 mg/kg (rats) or 200 mg/kg (mice) followed by AMF within 20–30 min (treatment was repeated 3-4-fold) has resulted in the complete regression of tumor in the 35% of rats and 57% of mice. Administration of MF alone or action of AMF alone has not resulted in tumor growth inhibition. The chemomodifying effect of nanohyperthermia was determined, in particular for cisplatinum: thermal enhancement ratio was 2.0. It was also observed that nanohyperthermia has resulted in the absence of 3LL metastases in 43% of mice. Conclusions. MF on the basis of lanthanum-strontium manganite may be considered as an effective inductor of tumor local hyperthermia.

On the in Vitro Hyperthermia of Magnetic Fluid in AC Magnetic Field

2009 ◽  
Author(s):  
Junfeng Jiang ◽  
Ruoyu Hong ◽  
Xiaohui Zhang ◽  
Hongzhong Li
Keyword(s):  
Magnetic Field ◽  
Magnetic Fluid ◽  
Volume Fraction ◽  
Maximum Temperature ◽  
Magnetic Fluid Hyperthermia ◽  
Ac Magnetic Field ◽  
Hyperthermia Therapy ◽  
Good Biocompatibility ◽  
High Chemical Stability

Hyperthermia therapy for cancer has attracted much attention nowadays. The study on the heat transfer in the magnetic fluid and the tumor is crucial for the successful application of magnetic fluid hyperthermia (MFH). Water-based Fe3O4 magnetic fluid is expected to be a most appropriate candidate for MFH due to the good biocompatibility, high saturation magnetization, super-paramagnetization and high chemical stability. In this paper, we explore the heat generation and transfer in magnetic fluid which is placed under an AC magnetic field. It is found that the amplitude and the frequency of alternating magnetic field, particle size and volume fraction have a pronounce influence on maximum temperature of hyperthermia.

scholarly journals Heating effect and biocompatibility of bacterial magnetosomes as potential materials used in magnetic fluid hyperthermia

2012 ◽  
Vol 22 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Rui-ting Liu ◽  
Jie Liu ◽  
Jie-qiong Tong ◽  
Tao Tang ◽  
Wei-Chao Kong ◽  
...  
Keyword(s):  
Magnetic Fluid ◽  
Heating Effect ◽  
Magnetic Fluid Hyperthermia ◽  
Materials Used
Sign in / Sign up

Export Citation Format

Share Document