scholarly journals Antibiotic mediated synthesis of gold nanoparticles with potent antimicrobial activity and their application in antimicrobial coatings

2010 ◽  
Vol 20 (32) ◽  
pp. 6789 ◽  
Author(s):  
Akhilesh Rai ◽  
Asmita Prabhune ◽  
Carole C. Perry
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles ◽  
Antimicrobial Coatings

scholarly journals Varied-shaped gold nanoparticles with nanogram killing efficiency as potential antimicrobial surface coatings for the medical devices

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ewelina Piktel ◽  
Łukasz Suprewicz ◽  
Joanna Depciuch ◽  
Sylwia Chmielewska ◽  
Karol Skłodowski ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Medical Devices ◽  
Multidrug Resistant ◽  
Resistance Mechanisms ◽  
Antimicrobial Spectrum ◽  
Antimicrobial Coatings ◽  
Low Toxicity ◽  
Spherical Gold Nanoparticles ◽  
Cost Efficient ◽  
Bactericidal Efficiency

AbstractMedical device-associated infections are a serious medical threat, particularly for patients with impaired mobility and/or advanced age. Despite a variety of antimicrobial coatings for medical devices being explored to date, only a limited number have been introduced for clinical use. Research into new bactericidal agents with the ability to eradicate pathogens, limit biofilm formation, and exhibit satisfactory biocompatibility, is therefore necessary and urgent. In this study, a series of varied-morphology gold nanoparticles in shapes of rods, peanuts, stars and spherical-like, porous ones with potent antibacterial activity were synthesized and thoroughly tested against spectrum of Candida albicans, Pseudomonas aeruginosa, Staphylococcus aureus clinical strains, as well as spectrum of uropathogenic Escherichia coli isolates. The optimization of gold nanoparticles synthesis allowed to develop nanomaterials, which are proved to be significantly more potent against tested microbes compared with the gold nanoformulations reported to date. Notably, their antimicrobial spectrum includes strains with different drug resistance mechanisms. Facile and cost-efficient synthesis of gold nanoparticles, remarkable bactericidal efficiency at nanogram doses, and low toxicity, underline their potential for development as a new coatings, as indicated by the example of urological catheters. The presented research fills a gap in microbial studies of non-spherical gold nanoparticles for the development of antimicrobial coatings targeting multidrug-resistant pathogens responsible for device-associated nosocomial infections.

scholarly journals Isolation and Optimization of Culture Conditions of Thraustochytrium kinnei for Biomass Production, Nanoparticle Synthesis, Antioxidant and Antimicrobial Activities

2021 ◽  
Vol 9 (6) ◽  
pp. 678
Author(s):  
Kaliyamoorthy Kalidasan ◽  
Nabikhan Asmathunisha ◽  
Venugopal Gomathi ◽  
Laurent Dufossé ◽  
Kandasamy Kathiresan
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles ◽  
Silver Nanoparticles ◽  
Biomass Production ◽  
Petroleum Ether Extract ◽  
Antimicrobial Activities ◽  
Culture Conditions ◽  
Gold And Silver Nanoparticles ◽  
Optimization Of Culture Conditions ◽  
Antioxidant And Antimicrobial Activities

This work deals with the identification of a predominant thraustochytrid strain, the optimization of culture conditions, the synthesis of nanoparticles, and the evaluation of antioxidant and antimicrobial activities in biomass extracts and nanoparticles. Thraustochytrium kinnei was identified as a predominant strain from decomposing mangrove leaves, and its culture conditions were optimized for maximum biomass production of 13.53 g·L−1, with total lipids of 41.33% and DHA of 39.16% of total fatty acids. Furthermore, the strain was shown to synthesize gold and silver nanoparticles in the size ranges of 10–85 nm and 5–90 nm, respectively. Silver nanoparticles exhibited higher total antioxidant and DPPH activities than gold nanoparticles and methanol extract of the strain. The silver nanoparticles showed higher antimicrobial activity than gold nanoparticles and petroleum ether extract of the strain. Thus, Thraustochytrium kinnei is proven to be promising for synthesis of silver nanoparticles with high antioxidant and antimicrobial activity.

Nanocomposite film with antimicrobial activity based on gold nanoparticles, chitosan and aminopropylsilane

2021 ◽  
pp. 127086
Author(s):  
Anike H. Virgili ◽  
Daniela C. Laranja ◽  
Patrícia S. Malheiros ◽  
Marcelo B. Pereira ◽  
Tania M.H. Costa ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles ◽  
Nanocomposite Film

Isolation, biosynthesis and antimicrobial activity of gold nanoparticles produced with extracts of Anabaena spiroides

2021 ◽  
Author(s):  
Chinmayee Priyadarshini Mandhata ◽  
Chita Ranjan Sahoo ◽  
Chandrika Saloni Mahanta ◽  
Rabindra Nath Padhy
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles

scholarly journals Synthesis of Gold Nanoparticles Using Leaf Extract of Ziziphus zizyphus and their Antimicrobial Activity

Nanomaterials ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. 174 ◽  
Author(s):  
Alaa Aljabali ◽  
Yazan Akkam ◽  
Mazhar Al Zoubi ◽  
Khalid Al-Batayneh ◽  
Bahaa Al-Trad ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles ◽  
Leaf Extract

scholarly journals Biosynthesis of Gold Nanoparticles Using Fusarium oxysporum f. sp. cubense JT1, a Plant Pathogenic Fungus

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Janki N. Thakker ◽  
Pranay Dalwadi ◽  
Pinakin C. Dhandhukia
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles ◽  
Chloride Solution ◽  
Pathogenic Fungus ◽  
Particle Size Analysis ◽  
Size Analysis ◽  
Plant Pathogenic Fungus ◽  
Extracellular Synthesis ◽  
Vis Spectroscopy ◽  
Methods Of Synthesis

The development of reliable processes for the synthesis of gold nanoparticles is an important aspect of current nanotechnology research. Recently, reports are published on the extracellular as well as intracellular biosynthesis of gold nanoparticles using microorganisms. However, these methods of synthesis are rather slow. In present study, rapid and extracellular synthesis of gold nanoparticles using a plant pathogenic fungus F. oxysporum f. sp. cubense JT1 (FocJT1) is reported. Incubation of FocJT1 mycelium with auric chloride solution produces gold nanoparticles in 60 min. Gold nanoparticles were characterized by UV-Vis spectroscopy, FTIR, and particle size analysis. The particles synthesized were of 22 nm sized, capped by proteins, and posed antimicrobial activity against Pseudomonas sp.

Biosynthesized gold nanoparticles as photocatalysts for selective degradation of cationic dye and their antimicrobial activity

2020 ◽  
Vol 400 ◽  
pp. 112704
Author(s):  
Rohit Kumar Singh ◽  
Saroj Sekhar Behera ◽  
Khushboo Rani Singh ◽  
Sourav Mishra ◽  
Bijayananda Panigrahi ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles ◽  
Cationic Dye ◽  
Selective Degradation

scholarly journals Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata

2019 ◽  
Vol 9 (2) ◽  
pp. 111-117 ◽  
Author(s):  
Aderonke Folorunso ◽  
Sunday Akintelu ◽  
Abel Kolawole Oyebamiji ◽  
Samuel Ajayi ◽  
Babawale Abiola ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Gold Nanoparticles ◽  
Annona Muricata ◽  
Leaf Extracts

scholarly journals Novel test procedure for testing antimicrobially active materials

2018 ◽  
Vol 4 (1) ◽  
pp. 229-231
Author(s):  
Alexander Stich ◽  
Sebastian Buhl ◽  
Clemens Bulitta
Keyword(s):  
Antimicrobial Activity ◽  
Standard Method ◽  
Test Procedure ◽  
Practical Application ◽  
Active Materials ◽  
Antimicrobial Coatings ◽  
Artificial Structure ◽  
Antimicrobial Test ◽  
Cleaning Procedures

AbstractAntimicrobial coatings are typically tested for their activity and effectiveness based on an artificial procedure, the standard JIS Z 2801 (or ISO 22196). The test samples are contaminated with a predetermined concentration of bacteria and covered with a sterile film. Due to the artificial structure of this process, however, there is always the question of the validity in the practical application of these surfaces and how comparable this germ-reducing effect is to currently common disinfection measures. Therefore, we developed a more realistic test procedure in our laboratory. The test samples are inoculated and incubated at standard room conditions. To compare the antimicrobial activity to standard cleaning procedures also disinfection and wipe controls were performed. The results show that the antimicrobial test patterns we use have a strong efficacy. This could be shown reproducibly both with the standard method JIS Z 2801 as well as with our new test procedure.

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