Identification of antibiotics using small molecule variable ligand display on gold nanoparticles

2010 ◽  
Vol 46 (40) ◽  
pp. 7516 ◽  
Author(s):  
Jamee Bresee ◽  
Keith E. Maier ◽  
Christian Melander ◽  
Daniel L. Feldheim
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule

Small Molecule- and Amino Acid-Induced Aggregation of Gold Nanoparticles

Langmuir ◽  
2013 ◽  
Vol 29 (25) ◽  
pp. 7661-7673 ◽  
Author(s):  
Hesham M. Zakaria ◽  
Akash Shah ◽  
Michael Konieczny ◽  
Joan A. Hoffmann ◽  
A. Jasper Nijdam ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Amino Acid ◽  
Small Molecule ◽  
Induced Aggregation

scholarly journals Colloidal Capsules Assembled from Gold Nanoparticles Using Small-Molecule Hydrophobic Cross-linkers

Langmuir ◽  
2019 ◽  
Vol 35 (52) ◽  
pp. 17037-17045
Author(s):  
Yijia Zhang ◽  
Wafa Abidi ◽  
Jacob M. Berlin
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule

scholarly journals Small molecule-decorated gold nanoparticles for preparing antibiofilm fabrics

2020 ◽  
Vol 2 (6) ◽  
pp. 2293-2302
Author(s):  
Le Wang ◽  
Michal Natan ◽  
Wenshu Zheng ◽  
Wenfu Zheng ◽  
Shaoqin Liu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Coating Technology ◽  
Ultrasound Assisted

By using ultrasound-assisted coating technology, we modified fabrics with N_Au NPs to fabricate antibiofilm fabrics.

Self-Assembled Monolayer Immobilized Gold Nanoparticles for Plasmonic Effects in Small Molecule Organic Photovoltaic

2013 ◽  
Vol 5 (3) ◽  
pp. 511-517 ◽  
Author(s):  
Ming-Chung Chen ◽  
Yi-Ling Yang ◽  
Shin-Wen Chen ◽  
Jia-Han Li ◽  
Muluken Aklilu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Organic Photovoltaic ◽  
Self Assembled Monolayer ◽  
Self Assembled ◽  
Plasmonic Effects

scholarly journals Colorimetric detection of protein via the terminal protection of small-molecule-linked DNA and unmodified gold nanoparticles

RSC Advances ◽  
2018 ◽  
Vol 8 (68) ◽  
pp. 38758-38764
Author(s):  
Jianwei Zhao ◽  
Cuiping Li ◽  
Guimin Ma ◽  
Wenhui Hao ◽  
Hongxia Jia
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Colorimetric Detection ◽  
Protein Detection ◽  
Target Protein

A novel colorimetric strategy for protein detection was developed based on unmodified gold nanoparticles (AuNPs) and terminal protection from a target protein.

scholarly journals Intratumoral diffusion patterns of small-molecule surface passivated Gold Nanoparticles quantified using in vivo micro-CT imaging

2021 ◽  
Author(s):  
Rossana Terracciano ◽  
Aobo Zang ◽  
E. Brian Butler ◽  
Danilo Demarchi ◽  
Jason Hafner ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Ct Imaging ◽  
Micro Ct ◽  
Molecule Surface

scholarly journals Gold Nanostars with Reduced Fouling Facilitate Small Molecule Detection in the Presence of Protein

Nanomaterials ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2565
Author(s):  
Anastasiia Tukova ◽  
Inga Christine Kuschnerus ◽  
Alfonso Garcia-Bennett ◽  
Yuling Wang ◽  
Alison Rodger
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Protein Corona ◽  
Surface Enhanced Raman Spectroscopy ◽  
Biological Media ◽  
Gold Nanostars ◽  
Cellular Environment ◽  
Vis Spectroscopy ◽  
Corona Formation

Gold nanoparticles have the potential to be used in biomedical applications from diagnostics to drug delivery. However, interactions of gold nanoparticles with different biomolecules in the cellular environment result in the formation of a “protein corona”—a layer of protein formed around a nanoparticle, which induces changes in the properties of nanoparticles. In this work we developed methods to reproducibly synthesize spheroidal and star-shaped gold nanoparticles, and carried out a physico-chemical characterization of synthesized anionic gold nanospheroids and gold nanostars through transmission electron microscopy (TEM), dynamic light scattering (DLS), zeta potential (ZP), nanoparticles tracking analysis (NTA), ultraviolet-visible (UV–Vis) spectroscopy and estimates of surface-enhanced Raman spectroscopy (SERS) signal enhancement ability. We analyzed how they interact with proteins after pre-incubation with bovine serum albumin (BSA) via UV–Vis, DLS, ZP, NTA, SERS, cryogenic TEM (cryo-TEM) and circular dichroism (CD) spectroscopy. The tests demonstrated that the protein adsorption on the particles’ surfaces was different for spheroidal and star shaped particles. In our experiments, star shaped particles limited the protein corona formation at SERS “hot spots”. This benefits the small-molecule sensing of nanostars in biological media. This work adds more understanding about protein corona formation on gold nanoparticles of different shapes in biological media, and therefore guides design of particles for studies in vitro and in vivo.

scholarly journals Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

2019 ◽  
Vol 7 (1) ◽  
pp. 113-124 ◽  
Author(s):  
Yu-Sang Sabrina Yang ◽  
Kelly D. Moynihan ◽  
Ahmet Bekdemir ◽  
Tanmay M. Dichwalkar ◽  
Michelle M. Noh ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
T Cells ◽  
Small Molecule ◽  
Small Molecule Drugs ◽  
Cell Penetrating

We sought to develop a nanoparticle vehicle that could deliver small molecule drugs to T cells.

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