Unusual radical addition on a heteroaromatic nitrogen. A convenient access to new pyrimidine derivatives

Yann Laot; Laurent Petit; Samir Z. Zard

doi:10.1039/c0cc00533a

Unusual radical addition on a heteroaromatic nitrogen. A convenient access to new pyrimidine derivatives

Chemical Communications ◽

10.1039/c0cc00533a ◽

2010 ◽

Vol 46 (31) ◽

pp. 5784 ◽

Cited By ~ 14

Author(s):

Yann Laot ◽

Laurent Petit ◽

Samir Z. Zard

Keyword(s):

Radical Addition ◽

Pyrimidine Derivatives ◽

Convenient Access

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ChemInform Abstract: Unusual Radical Addition on a Heteroaromatic Nitrogen. A Convenient Access to New Pyrimidine Derivatives.

ChemInform ◽

10.1002/chin.201051162 ◽

2010 ◽

Vol 41 (51) ◽

pp. no-no

Author(s):

Yann Laot ◽

Laurent Petit ◽

Samir Z. Zard

Keyword(s):

Radical Addition ◽

Pyrimidine Derivatives ◽

Convenient Access

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ChemInform Abstract: Convenient Access to New 4-Substituted Aminopyrido[2,3-d]pyrimidine Derivatives.

ChemInform ◽

10.1002/chin.201609185 ◽

2016 ◽

Vol 47 (9) ◽

pp. no-no

Author(s):

Fatima Belhadj ◽

Zahira Kibou ◽

Nawel Cheikh ◽

Noureddine Choukchou-Braham ◽

Didier Villemin

Keyword(s):

Pyrimidine Derivatives ◽

Convenient Access

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Iron-Catalyzed Tandem Radical Addition/Cyclization: Highly Efficient Access to Methylated Quinoline-2,4-diones

Synlett ◽

10.1055/s-0039-1691574 ◽

2020 ◽

Vol 31 (20) ◽

pp. 2049-2053

Author(s):

Ji-Kai Liu ◽

Huan Sun ◽

Yue Jiang ◽

Ming-Kun Lu ◽

Yun-Yun Li ◽

...

Keyword(s):

Visible Light ◽

Dimethyl Sulfoxide ◽

Functional Group ◽

Cascade Reaction ◽

Radical Addition ◽

Highly Efficient ◽

Efficient Access ◽

Convenient Access

A visible-light-induced and iron-catalyzed oxidative radical addition/cyclization cascade reaction of N-(o-cyanoaryl)acrylamides with dimethyl sulfoxide has been developed. The method exhibits a wide substrate scope and an excellent functional-group tolerance, thus providing an efficient and convenient access to a variety of methylated quinoline-2,4-diones.

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Aerobic thiyl radical addition/cyclization of N-methacryloyl benzamides for the synthesis of isoquinoline-1,3(2H,4H)-dione derivatives

Organic & Biomolecular Chemistry ◽

10.1039/c7ob01552f ◽

2017 ◽

Vol 15 (35) ◽

pp. 7330-7338 ◽

Cited By ~ 12

Author(s):

Yan-qin Yuan ◽

Pailla Santhosh Kumar ◽

Chun-niu Zhang ◽

Ming-hua Yang ◽

Sheng-rong Guo

Keyword(s):

Radical Addition ◽

Thiyl Radical ◽

Highly Effective ◽

Convenient Access

A highly effective dioxygen-triggered oxidative thiyl radical addition/cyclization of N-methacryloylbenzamides was explored. This method provides convenient access to a variety of useful sulfide-containing 4,4-disubstituted isoquinoline-1,3-diones.

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