Identifying drug metallation sites on peptides using electron transfer dissociation (ETD), collision induced dissociation (CID) and ion mobility-mass spectrometry (IM-MS)

2010 ◽  
Vol 46 (30) ◽  
pp. 5458 ◽  
Author(s):  
Jonathan P. Williams ◽  
Jeffery M. Brown ◽  
Iain Campuzano ◽  
Peter J. Sadler
Keyword(s):  
Mass Spectrometry ◽  
Electron Transfer ◽  
Ion Mobility ◽  
Electron Transfer Dissociation ◽  
Collision Induced Dissociation ◽  
Ion Mobility Mass Spectrometry

Obtaining complementary polypeptide sequence information from a single precursor ion packet via sequential ion mobility-resolved electron transfer and vibrational activation

The Analyst ◽  
2015 ◽  
Vol 140 (21) ◽  
pp. 7175-7183 ◽  
Author(s):  
Deepali Rathore ◽  
Forouzan Aboufazeli ◽  
Eric D. Dodds
Keyword(s):  
Electron Transfer ◽  
Ion Mobility ◽  
Electron Transfer Dissociation ◽  
Collision Induced Dissociation ◽  
Sequence Information ◽  
Polypeptide Sequence ◽  
Single Precursor

Electron transfer, ion mobility, and vibrational activation are combined to obtain temporally-resolved electron transfer dissociation and collision-induced dissociation spectra from a single packet of protonated polypeptide ions.

Possible isomers in ligand protected Ag11cluster ions identified by ion mobility mass spectrometry and fragmented by surface induced dissociation

2016 ◽  
Vol 52 (19) ◽  
pp. 3805-3808 ◽  
Author(s):  
Ananya Baksi ◽  
Sophie R. Harvey ◽  
Ganapati Natarajan ◽  
Vicki H. Wysocki ◽  
Thalappil Pradeep
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility ◽  
Collision Induced Dissociation ◽  
Silver Clusters ◽  
Ion Mobility Mass Spectrometry ◽  
Surface Induced Dissociation

Isomeric glutathione protected silver clusters have been detected using ion mobility mass spectrometry. This cluster has been fragmented by conventional collision induced dissociation and newly introduced surface induced dissociation.

scholarly journals Electron transfer with no dissociation ion mobility–mass spectrometry (ETnoD IM-MS). The effect of charge reduction on protein conformation

2017 ◽  
Vol 413 ◽  
pp. 43-51 ◽  
Author(s):  
Jacquelyn R. Jhingree ◽  
Rebecca Beveridge ◽  
Eleanor R. Dickinson ◽  
Jonathan P. Williams ◽  
Jeffery M. Brown ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Transfer ◽  
Ion Mobility ◽  
Protein Conformation ◽  
Ion Mobility Mass Spectrometry ◽  
Charge Reduction
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