Thionine/nanogold multilayer film for electrochemical immunoassay of alpha-fetoprotein in human serum using biofunctional double-codified gold nanoparticles

2010 ◽  
Vol 2 (11) ◽  
pp. 1702 ◽  
Author(s):  
Biling Su ◽  
Juan Tang ◽  
Huafeng Chen ◽  
Jianxin Huang ◽  
Guonan Chen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Human Serum ◽  
Multilayer Film ◽  
Alpha Fetoprotein ◽  
Electrochemical Immunoassay

Enzyme-catalyzed silver deposition on irregular-shaped gold nanoparticles for electrochemical immunoassay of alpha-fetoprotein

2012 ◽  
Vol 755 ◽  
pp. 62-68 ◽  
Author(s):  
Wenqiang Lai ◽  
Dianping Tang ◽  
Xiaohua Que ◽  
Junyang Zhuang ◽  
Libing Fu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Alpha Fetoprotein ◽  
Electrochemical Immunoassay ◽  
Silver Deposition

Electrochemical immunoassay of carcinoembryonic antigen based on TiO2–graphene / thionine / gold nanoparticles composite

2012 ◽  
Vol 90 (7) ◽  
pp. 608-615 ◽  
Author(s):  
Ke-Jing Huang ◽  
Zhi-Wei Wu ◽  
Ying-Ying Wu ◽  
Yan-Ming Liu
Keyword(s):  
Gold Nanoparticles ◽  
Carcinoembryonic Antigen ◽  
Linear Response ◽  
Multilayer Film ◽  
Electrostatic Force ◽  
Carbon Electrode ◽  
Electrochemical Immunoassay ◽  
Amino Groups ◽  
Amperometric Immunosensor ◽  
Highly Sensitive

A novel multilayer film based on gold nanoparticles (AuNPs), thionine (Thi), and TiO2–graphene (TiO2–Gr) was exploited to develop a highly sensitive amperometric immunosensor for detecting carcinoembryonic antigen (CEA). Firstly, Nafion–TiO2–Gr homogeneous composite was dropped on the surface of a glassy carbon electrode (GCE). Then Thi was chemisorbed by the TiO2–Gr–Nafion composite. Furthermore, the negative ly charged AuNPs were chemisorbed onto Thi film through the electrostatic force with the amino groups of Thi. Cyclic voltammetry (CV) was employed to characterize the assembly process and the performance of the immunosensor. Because of the synergistic effect of the AuNPs, Thi, and the unique properties of TiO2–Gr, the obtained immunosensor exhibited a wide linear response to CEA in two ranges from 0.1 to 10.0 ng mL−1 and from 10.0 to 120.0 ng mL−1 with a relatively low detection limit of 0.01 ng mL−1 (S/N = 3), as well as good stability and repeatability.

Construction of Boronate-Affinity Magnetic Immunity SERS Sensor and Detection of Alpha-Fetoprotein (AFP) in Human Serum

2021 ◽  
Vol 94 (3) ◽  
pp. 860-868
Author(s):  
Yuhan He ◽  
Lijun Li ◽  
Xiaoxuan Li ◽  
Chubing Lin ◽  
Yan Zhang
Keyword(s):  
Human Serum ◽  
Alpha Fetoprotein

Layer-by-layer self-assembly of 2D graphene nanosheets, 3D copper oxide nanoflowers and 0D gold nanoparticles for ultrasensitive electrochemical detection of alpha fetoprotein

RSC Advances ◽  
2015 ◽  
Vol 5 (70) ◽  
pp. 56583-56589 ◽  
Author(s):  
Yulan Wang ◽  
Dan Wu ◽  
Yong Zhang ◽  
Xiang Ren ◽  
Yaoguang Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Copper Oxide ◽  
Electrochemical Detection ◽  
Self Assembly ◽  
Graphene Nanosheets ◽  
Electrochemical Immunosensor ◽  
Alpha Fetoprotein ◽  
Quantitative Detection ◽  
Layer By Layer ◽  
Label Free

In this work, a novel and ultrasensitive label-free electrochemical immunosensor was developed for the quantitative detection of alpha fetoprotein (AFP).

scholarly journals Gold nanoparticles increases UV and thermal stability of human serum albumin

2016 ◽  
Vol 11 (4) ◽  
pp. 04B310 ◽  
Author(s):  
Robin Capomaccio ◽  
Inês Osório ◽  
Isaac Ojea-Jiménez ◽  
Giacomo Ceccone ◽  
Pascal Colpo ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Gold Nanoparticles ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Thermal Stability Of
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