Photoacid generator formation for the selective enrichment of perfluoroalkyl sulfonates and their direct analysis by MALDI-TOF-MS

The Analyst ◽  
2011 ◽  
Vol 136 (11) ◽  
pp. 2225 ◽  
Author(s):  
Dong Cao ◽  
Ming Hu ◽  
Chunguang Han ◽  
Jiyao Yu ◽  
Lin Cui ◽  
...  
Keyword(s):  
Direct Analysis ◽  
Maldi Tof Ms ◽  
Selective Enrichment ◽  
Maldi Tof ◽  
Photoacid Generator ◽  
Tof Ms

Development of magnetic LuPO4 microspheres for highly selective enrichment and identification of phosphopeptides for MALDI-TOF MS analysis

2015 ◽  
Vol 3 (48) ◽  
pp. 9330-9339 ◽  
Author(s):  
Xing-yu Long ◽  
Qun Song ◽  
Hong-zhen Lian
Keyword(s):  
Core Shell ◽  
Maldi Tof Ms ◽  
Selective Enrichment ◽  
Maldi Tof ◽  
Ms Analysis ◽  
Tof Ms

Lichee-like core–shell structured magnetic lutetium phosphate (Fe3O4@LuPO4) affinity microspheres were synthesized, characterized and successfully applied to enrich phosphopeptides.

Rapid Pathogen Identification With Direct Application of MALDI-TOF Mass Spectrometry on an Endophthalmitis Vitreous Sample Without Prior Culture

2019 ◽  
Vol 3 (4) ◽  
pp. 255-259 ◽  
Author(s):  
Lindsay Y. Chun ◽  
Laura Dolle Molle ◽  
Olaf Schneewind ◽  
Dominique Missiakas ◽  
Kathleen G. Beavis ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Direct Analysis ◽  
Causative Organism ◽  
Pathogen Identification ◽  
Maldi Tof Ms ◽  
Hand Motion ◽  
Maldi Tof ◽  
Microbiological Methods ◽  
Vitreous Sample ◽  
Tof Ms

Purpose:We report a case of a 72-year-old man with bleb-related endophthalmitis (BRE) whose vitreous samples were directly analyzed with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to rapidly identify the causative organism, whereas the results from conventional microbiological techniques were negative.Methods:We analyzed BRE vitreous samples with MALDI-TOF MS (Vitek MS, bioMérieux) for rapid pathogen identification without prior culture. Samples were also analyzed with standard microbiological methods.Results:Within 1 hour of sample acquisition, MALDI-TOF MS identified Gemella sanguinis from the undiluted vitreous sample from vitrectomy without prior culture with a confidence value of 99.7%. Gram stain and cultures from aqueous and vitreous samples were negative for 28 days after acquisition. The patient’s right-eye vision improved from hand motion to 20/50 2 months later.Conclusions:Our findings suggest that the direct analysis of intraocular samples with MALDI-TOF MS could be a novel, promising adjuvant method of rapid endophthalmitis diagnosis.

Characterization of Phosphopeptides Using a Combination of Immobilized Metal Ion Affinity Media and Direct Analysis by MALDI-TOF-MS

2007 ◽  
Vol 2007 (8) ◽  
pp. pdb.prot4618-pdb.prot4618
Author(s):  
L. J. Deterding ◽  
J. M. Cutalo ◽  
K. B. Tomer
Keyword(s):  
Metal Ion ◽  
Direct Analysis ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

Direct analysis of positive blood cultures using MALDI-TOF MS profiling and a fundamentally improved sample preparation technique

Pathology ◽  
2011 ◽  
Vol 43 ◽  
pp. S73-S74
Author(s):  
Guido Mix ◽  
Leith Fremlin ◽  
Thomas Maier ◽  
Beatrix Wegemann ◽  
Markus Kostrzewa
Keyword(s):  
Sample Preparation ◽  
Direct Analysis ◽  
Blood Cultures ◽  
Preparation Technique ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Sample Preparation Technique ◽  
Tof Ms

Magnetic metal–organic frameworks for selective enrichment and exclusion of proteins for MALDI-TOF MS analysis

The Analyst ◽  
2016 ◽  
Vol 141 (15) ◽  
pp. 4568-4572 ◽  
Author(s):  
Wei Wan ◽  
Qionglin Liang ◽  
Xiaoqiong Zhang ◽  
Min Yan ◽  
Mingyu Ding
Keyword(s):  
Metal Organic Frameworks ◽  
Maldi Tof Ms ◽  
Selective Enrichment ◽  
Maldi Tof ◽  
Ms Analysis ◽  
Magnetic Metal ◽  
Metal Organic ◽  
Tof Ms

We firstly report magnetic metal–organic frameworks for selective enrichment and exclusion of proteins for MALDI-TOF MS analysis.

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