A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands

2010 ◽  
Vol 8 (13) ◽  
pp. 2926 ◽  
Author(s):  
John E. Moses ◽  
Dougal J. Ritson ◽  
Fengzhi Zhang ◽  
Caterina Maria Lombardo ◽  
Shozeb Haider ◽  
...  
Keyword(s):  
Click Chemistry ◽  
G Quadruplex

Amino acid‐anthraquinone click chemistry conjugates selectively target human telomeric G‐quadruplex

ChemMedChem ◽  
2021 ◽  
Author(s):  
Alberto Ongaro ◽  
Giovanni Desiderati ◽  
Erika Oselladore ◽  
Davide Auricchio ◽  
Maurizio Memo ◽  
...  
Keyword(s):  
Amino Acid ◽  
Click Chemistry ◽  
G Quadruplex

scholarly journals Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry

2012 ◽  
Vol 51 (44) ◽  
pp. 11073-11078 ◽  
Author(s):  
Marco Di Antonio ◽  
Giulia Biffi ◽  
Angelica Mariani ◽  
Eun-Ang Raiber ◽  
Raphaël Rodriguez ◽  
...  
Keyword(s):  
Click Chemistry ◽  
G Quadruplex

scholarly journals Inside Cover: Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry (Angew. Chem. Int. Ed. 44/2012)

2012 ◽  
Vol 51 (44) ◽  
pp. 10906-10906
Author(s):  
Marco Di Antonio ◽  
Giulia Biffi ◽  
Angelica Mariani ◽  
Eun-Ang Raiber ◽  
Raphaël Rodriguez ◽  
...  
Keyword(s):  
Click Chemistry ◽  
G Quadruplex

Intra-molecular G-quadruplex structure generated by DNA-templated click chemistry: “Turn-on” fluorescent probe for copper ions

2014 ◽  
Vol 55 ◽  
pp. 187-194 ◽  
Author(s):  
Qinpeng Shen ◽  
Lifen Zhou ◽  
Yijia Yuan ◽  
Yan Huang ◽  
Binbin Xiang ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Fluorescent Probe ◽  
Copper Ions ◽  
Turn On ◽  
Quadruplex Structure ◽  
G Quadruplex

scholarly journals Conformation of G-quadruplex Controlled by Click Reaction

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4339
Author(s):  
Chao-Da Xiao ◽  
Zhi-Yong He ◽  
Chuan-Xin Guo ◽  
Xiang-Chun Shen ◽  
Yan Xu
Keyword(s):  
Click Chemistry ◽  
Dna Sequence ◽  
Click Reaction ◽  
Secondary Structures ◽  
Biological Processes ◽  
Biological Importance ◽  
Intense Fluorescence ◽  
G Quadruplex ◽  
First Time

G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging. In this study, we described a method for regulating G-quadruplex conformation by click chemistry for the first time. 8-ethynyl-2′-deoxyguanosine was synthesized and incorporated into a 12-nt telomere DNA sequence. Such a sequence, at first, formed mixed parallel/anti-parallel G-quadruplexes, while it changed to anti-parallel after reaction with azidobenzene. Meanwhile, the click reaction can give the sequence intense fluorescence.

Discovery of Novel 11-Triazole Substituted Benzofuro[3,2-b]quinolone Derivatives as c-myc G-Quadruplex Specific Stabilizers via Click Chemistry

2017 ◽  
Vol 60 (13) ◽  
pp. 5407-5423 ◽  
Author(s):  
De-Ying Zeng ◽  
Guo-Tao Kuang ◽  
Shi-Ke Wang ◽  
Wang Peng ◽  
Shu-Ling Lin ◽  
...  
Keyword(s):  
Click Chemistry ◽  
G Quadruplex ◽  
Quinolone Derivatives

Conjugation of hemin to G-quadruplex forming oligonucleotide using click chemistry

2017 ◽  
Vol 101 ◽  
pp. 799-804 ◽  
Author(s):  
J. Kosman ◽  
A. Stanislawska ◽  
A. Gluszynska ◽  
B. Juskowiak
Keyword(s):  
Click Chemistry ◽  
G Quadruplex

scholarly journals A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Ming-Hao Hu ◽  
Xiao Chen ◽  
Shuo-Bin Chen ◽  
Tian-Miao Ou ◽  
Meicun Yao ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Fluorescent Probe ◽  
G Quadruplex
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