The role of mass transport pathway in wormholelike mesoporous carbon for supercapacitors

2010 ◽  
Vol 12 (36) ◽  
pp. 10842 ◽  
Author(s):  
Yeru Liang ◽  
Fengxue Liang ◽  
Zhenghui Li ◽  
Dingcai Wu ◽  
Fangyu Yan ◽  
...  
2004 ◽  
Vol 287 (4) ◽  
pp. L843-L851 ◽  
Author(s):  
Christie P. Thomas ◽  
Jason R. Campbell ◽  
Patrick J. Wright ◽  
Russell F. Husted

H441 cells, a bronchiolar epithelial cell line, develop a cAMP-regulated benzamil-sensitive Na+ transport pathway on permeable supports (Itani OA, Auerbach SD, Husted RF, Volk KA, Ageloff S, Knepper MA, Stokes JB, Thomas CP. Am J Physiol Lung Cell Mol Physiol 282: L631–L641, 2002). To understand the molecular basis for the stimulation of Na+ transport, we delineated the role of specific intracellular pathways and examined the effect of cAMP on αβγ-epithelial Na+ channel (ENaC) and sgk1 expression. Na+ transport increases within 5 min of cAMP stimulation and is sustained for >24 h. The sustained effect of cAMP on Na+ transport is abolished by LY-294002, an inhibitor of phosphatidylinositol 3-kinase, by H89, an inhibitor of PKA, or by SB-202190, an inhibitor of p38 MAP kinase. The sustained effect of cAMP was associated with increases in α-ENaC mRNA and protein but without a detectable increase in βγ-ENaC and sgk1. The early effect of cAMP on Na+ transport is brefeldin sensitive and is mediated via PKA. These results are consistent with a model where the early effect of cAMP is to increase trafficking of Na+ channels to the apical cell surface whereas the sustained effect requires the synthesis of α-ENaC.


1990 ◽  
Vol 23 (6) ◽  
pp. 188-194 ◽  
Author(s):  
Toivo T. Kodas ◽  
Paul B. Comita
Keyword(s):  

2020 ◽  
Vol 40 (5) ◽  
pp. 789-807
Author(s):  
G. H. Browne ◽  
S. Bull ◽  
M. J. Arnot ◽  
A. F. Boyes ◽  
P. R. King ◽  
...  

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