Experimental evidence of chemical exchange over the β(1→3) glycosidic linkage and hydrogen bonding involving hydroxy protons in hyaluronan oligosaccharides by NMR spectroscopy

2010 ◽  
Vol 8 (12) ◽  
pp. 2795 ◽  
Author(s):  
Gustav Nestor ◽  
Lennart Kenne ◽  
Corine Sandström
Keyword(s):  
Hydrogen Bonding ◽  
Nmr Spectroscopy ◽  
Experimental Evidence ◽  
Chemical Exchange ◽  
Glycosidic Linkage

NMR Study on Hydroxy Protons of κ- and κ/μ-Hybrid Carrageenan Oligosaccharides: Experimental Evidence of Hydrogen Bonding and Chemical Exchange Interactions in κ/μ Oligosaccharides

2010 ◽  
Vol 11 (12) ◽  
pp. 3487-3494 ◽  
Author(s):  
Eric Morssing Vilén ◽  
Lena C. E. Lundqvist ◽  
Diane Jouanneau ◽  
William Helbert ◽  
Corine Sandström
Keyword(s):  
Hydrogen Bonding ◽  
Experimental Evidence ◽  
Chemical Exchange ◽  
Exchange Interactions ◽  
Nmr Study

scholarly journals Exploring the Structural Chemistry of Pyrophosphoramides: N,N′,N″,N‴-Tetraisopropylpyrophosphoramide

Chemistry ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 149-163
Author(s):  
Duncan Micallef ◽  
Liana Vella-Zarb ◽  
Ulrich Baisch
Keyword(s):  
Crystal Structure ◽  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Hydrogen Bonding ◽  
Nmr Spectroscopy ◽  
Ir Spectroscopy ◽  
Room Temperature ◽  
Intermolecular Hydrogen Bonding ◽  
X Ray Diffraction ◽  
X Ray

N,N′,N″,N‴-Tetraisopropylpyrophosphoramide 1 is a pyrophosphoramide with documented butyrylcholinesterase inhibition, a property shared with the more widely studied octamethylphosphoramide (Schradan). Unlike Schradan, 1 is a solid at room temperature making it one of a few known pyrophosphoramide solids. The crystal structure of 1 was determined by single-crystal X-ray diffraction and compared with that of other previously described solid pyrophosphoramides. The pyrophosphoramide discussed in this study was synthesised by reacting iso-propyl amine with pyrophosphoryl tetrachloride under anhydrous conditions. A unique supramolecular motif was observed when compared with previously published pyrophosphoramide structures having two different intermolecular hydrogen bonding synthons. Furthermore, the potential of a wider variety of supramolecular structures in which similar pyrophosphoramides can crystallise was recognised. Proton (1H) and Phosphorus 31 (31P) Nuclear Magnetic Resonance (NMR) spectroscopy, infrared (IR) spectroscopy, mass spectrometry (MS) were carried out to complete the analysis of the compound.

scholarly journals IDENTIFICATION AND SEQUENCING BY NMR SPECTROSCOPY OF THE CARBOHYDRATE MOIETY IN A SAPONIN FROM Barringtonia asiatica

2010 ◽  
Vol 1 (3) ◽  
pp. 120-124
Author(s):  
Rymond J Rumampuk
Keyword(s):  
Nmr Spectroscopy ◽  
13C Nmr ◽  
Coupling Constants ◽  
Carbohydrate Moiety ◽  
Glycosidic Linkage ◽  
1H And 13C Nmr ◽  
Heteronuclear Correlation ◽  
Vicinal Coupling Constants ◽  
Nmr Signals

A trisaccharide chain in a saponin from the seeds of Barringtonia asiatica has been identified and sequenced as {[b-D-galactopyranosyl(1®3)- b-D-glucopyranosyl(1®2)]-b-D-glucuronopyranosyloxy} using a combination of homonuclear and heteronuclear correlation NMR spectroscopy. The 1H and 13C NMR signals of the sugar residues can be determined and distinguished from one other by use of the HMQC-TOCSY technique. Anomeric configurations were unambiguously assigned from the vicinal coupling constants 3JH-1,H-2 of the anomeric protons. Inter-glycosidic linkage assignments were elucidated using  HMBC.   Keyword: Barringtonia asiatica, carbohydrate, saponin, NMR

Conformational flexibility of C-glycosides: Experimental evidence of the existence of a gauche-gauche confirmation around the glycosidic linkage for a lactose analogue

1996 ◽  
Vol 37 (9) ◽  
pp. 1467-1470 ◽  
Author(s):  
Juan-Félix Espinosa ◽  
Hansjörg Dietrich ◽  
Manuel Martín-Lomas ◽  
Richard R. Schmidt ◽  
Jesús Jiménez-Barbero
Keyword(s):  
Experimental Evidence ◽  
Conformational Flexibility ◽  
Glycosidic Linkage
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