Enantioselective desymmetrizing palladium catalyzed carbonylation reactions: the catalytic asymmetric synthesis of quaternary carbon center containing 1,3-dienes

2010 ◽  
Vol 8 (4) ◽  
pp. 758-760 ◽  
Author(s):  
Simon J. Byrne ◽  
Anthony J. Fletcher ◽  
Paul Hebeisen ◽  
Michael C. Willis
RSC Advances ◽  
2016 ◽  
Vol 6 (88) ◽  
pp. 85058-85062 ◽  
Author(s):  
Mayaka Maeno ◽  
Hiroya Kondo ◽  
Etsuko Tokunaga ◽  
Norio Shibata

Catalytic asymmetric synthesis of fluorinated donepezil, a promising new therapeutic agent for Alzheimer's disease, was achieved.


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