Metal complexes as photochemical nitric oxide precursors: Potential applications in the treatment of tumors

2009 ◽  
pp. 10660 ◽  
Author(s):  
Alexis D. Ostrowski ◽  
Peter C. Ford
Keyword(s):  
Nitric Oxide ◽  
Metal Complexes ◽  
Potential Applications

Retracted Article: Light-triggered nitric oxide release and targeted fluorescence imaging in tumor cells developed from folic acid-graft-carboxymethyl chitosan nanospheres

RSC Advances ◽  
2014 ◽  
Vol 4 (57) ◽  
pp. 30129-30136 ◽  
Author(s):  
Rijun Gui ◽  
Ajun Wan ◽  
Yalei Zhang ◽  
Huili Li ◽  
Tingting Zhao
Keyword(s):  
Nitric Oxide ◽  
Folic Acid ◽  
Tumor Cells ◽  
Fluorescence Imaging ◽  
Carboxymethyl Chitosan ◽  
Nitric Oxide Release ◽  
No Release ◽  
Retracted Article ◽  
Potential Applications

This article reported the synthesis of CMC–FA–RBS(CQD) nanospheres and studied their potential applications for NO release and fluorescence imaging.

scholarly journals Schiff base metal complex as a potential therapeutic drug in medical science: A critical review

BIBECHANA ◽  
2021 ◽  
Vol 18 (1) ◽  
pp. 214-230
Author(s):  
Narendra Kumar Chaudhary ◽  
Biswash Guragain ◽  
Siyanand Kumar Chaudhary ◽  
Parashuram Mishra
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Medical Science ◽  
Emerging Diseases ◽  
Therapeutic Drug ◽  
Significant Research ◽  
Potential Applications ◽  
Global Threat ◽  
Schiff Base Metal Complexes

The discovery of new chemotherapeutics with novel bioactivities and functionalities to fight current emerging diseases has become the most significant research in pharmaceutical science. Schiff bases are versatile pharmacophores that can form complexes by chelation with metals of different oxidation states. Over a few decades of intensive research on metal-based drugs, Schiff base metal complexes have been considered as the active field of research in coordination chemistry, owing to their valuable applications in various fields of science. As therapeutic drugs, they have potential applications as antibiotic, antimicrobial, antitumor, antiviral, anti-inflammatory, analgesic, antifungal, and many more. There has been a global threat of drug resistance in medical science in recent years because most of the pathogenic organisms are developing the ability to deactivate drug substances. For this reason, it requires urgent attention from chemical and pharmaceutical scientists to address the severe challenges of multidrug resistance. This review summarizes the current developments in the last few decades' research on the chemotherapeutic activities of Schiff base metal complexes. BIBECHANA 18 (2021) 214-230

Ultrafast Photochemistry of a Molybdenum Carbonyl-Nitrosyl Complex with a Triazacyclononane Coligand

2021 ◽  
Author(s):  
Niklas Gessner ◽  
Anna Karina Bäck ◽  
Johannes Knorr ◽  
Christoph Nagel ◽  
Philipp Marquetand ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Carbon Monoxide ◽  
Transition Metal ◽  
Metal Complexes ◽  
Small Molecules ◽  
Transition Metal Complexes ◽  
Nitrosyl Complex ◽  
Molybdenum Carbonyl

Transition metal complexes capable of releasing small molecules such as carbon monoxide and nitric oxide upon photoactivation are versatile tools in various fields of chemistry and biology. In this work,...

scholarly journals Molecular design of luminescent metal-based materials

2001 ◽  
Vol 73 (3) ◽  
pp. 543-548 ◽  
Author(s):  
Vivian Wing-Wah Yam
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Building Block ◽  
Molecular Design ◽  
Metal Chalcogenide ◽  
Potential Applications ◽  
Photochemical Properties ◽  
Polynuclear Metal Complexes ◽  
Luminescence Behavior

A series of soluble di- and polynuclear transition-metal acetylides with rich luminescence behavior have been designed and successfully isolated. The photophysical and photochemical properties have been studied. Luminescent polynuclear metal complexes have also been obtained based on the metal chalcogenide building block. These high-nuclearity transition-metal chalcogenide complexes have been structurally characterized and shown to display rich luminescence behavior. Various approaches and strategies to design and synthesize luminescent polynuclear metal complexes that may find potential applications as chemosensors and luminescence signalling devices will also be described.

scholarly journals Half- and mixed-sandwich metallacarboranes for potential applications in medicine

2019 ◽  
Vol 91 (4) ◽  
pp. 563-573 ◽  
Author(s):  
Marta Gozzi ◽  
Benedikt Schwarze ◽  
Evamarie Hey-Hawkins
Keyword(s):  
Organic Chemistry ◽  
Transition Metal ◽  
Transition Metals ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Structural Features ◽  
Biological Stability ◽  
Potential Applications ◽  
Sandwich Type ◽  
Isolobal Analogy

Abstract Today, medicinal chemistry is still clearly dominated by organic chemistry, and commercially available boron-based drugs are rare. In contrast to hydrocarbons, boranes prefer the formation of polyhedral clusters via delocalized 3c2e bonds, such as polyhedral dicarba-closo-dodecaborane(12) (closo-C2B10H12). These clusters have remarkable biological stability, and the three isomers, 1,2- (ortho), 1,7- (meta), and 1,12-dicarba-closo-dodecaborane(12) (para), have attracted much interest due to their unique structural features. Furthermore, anionic nido clusters ([7,8-C2B9H11]2−), derived from the neutral icosahedral closo cluster 1,2-dicarba-closo-dodecaborane(12) by deboronation followed by deprotonation are suitable ligands for transition metals and offer the possibility to form metallacarboranes, for example via coordination through the upper pentagonal face of the cluster. The isolobal analogy between the cyclopentadienyl(–1) ligand (Cp−) and [C2B9H11]2− clusters (dicarbollide anion, Cb2−) is the motivation in using Cb2− as ligand for coordination to a metal center to design compounds for various applications. This review focuses on potential applications of half- and mixed-sandwich-type transition metal complexes in medicine.

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