A simple approach for the discrimination of nucleotides based on a water-soluble polythiophene derivative

2009 ◽  
pp. 4696 ◽  
Author(s):  
Zhiyi Yao ◽  
Xueling Feng ◽  
Wenjing Hong ◽  
Chun Li ◽  
Gaoquan Shi
Keyword(s):  
Simple Approach ◽  
Water Soluble ◽  
Polythiophene Derivative

Efficient and Green Synthesis of Bis(indolyl)Methanes using Thiamine Hydrochloride as an Organocatalyst: A Parallel Scrutiny of Microwave Irradiation versus Ultrasonicator Heating in Water

2020 ◽  
Vol 17 (8) ◽  
pp. 679-684
Author(s):  
Nitin M. Thorat ◽  
Kiran D. Dhawale ◽  
Sandeep B. Kasar ◽  
Manali S. Thopate ◽  
Limbraj R. Patil ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Aqueous Media ◽  
Vitamin B1 ◽  
Simple Approach ◽  
Water Soluble ◽  
High Yield ◽  
Thiamine Hydrochloride ◽  
Short Reaction Time ◽  
Alternative Approach ◽  
Solvent Free Conditions

Thiamine hydrochloride is reported to be a highly competent promoter for the synthesis of bis(indolyl)methanes under solvent free conditions using microwave irradiation and ultrasonicator heating in aqueous media. Vitamin B1 is an economical, non-toxic, nonflammable and water soluble green organocatalyst. Moreover, the simple approach, easily operational, short reaction time, high yield and using a little quantity of thiamine hydrochloride makes this method an alternative approach. Present protocol is a simple and eco-friendly approach for the synthesis of bis(indolyl)methanes under microwave and ultrasonicator conditions.

scholarly journals Molecular Doping of a Water‐Soluble Polythiophene Derivative

2019 ◽  
Vol 216 (12) ◽  
pp. 1800772
Author(s):  
Johanna Zessin ◽  
Eva Bittrich ◽  
Jakob Zessin ◽  
Mikhail Malanin ◽  
Juliane Posseckardt ◽  
...  
Keyword(s):  
Water Soluble ◽  
Molecular Doping ◽  
Polythiophene Derivative

Fluorescence and colorimetric detection of ATP based on a strategy of self-promoting aggregation of a water-soluble polythiophene derivative

2015 ◽  
Vol 51 (40) ◽  
pp. 8544-8546 ◽  
Author(s):  
Dandan Cheng ◽  
Yandong Li ◽  
Jing Wang ◽  
Yujiao Sun ◽  
Lu Jin ◽  
...  
Keyword(s):  
Detection Limit ◽  
Colorimetric Detection ◽  
Water Soluble ◽  
Side Chain ◽  
Polythiophene Derivative

A sensitive fluorescent and colorimetric dual-modal probe for the detection of ATP has been developed based on a strategy of self-promoting aggregation of a cationic polythiophene derivative bearing anthracene groups in the side chain with a detection limit as low as 10−9 M.

A new water-soluble polythiophene derivative as a probe for real-time monitoring adenosine 5′-triphosphatase activity in lysosome of living cells

Talanta ◽  
2018 ◽  
Vol 182 ◽  
pp. 396-404 ◽  
Author(s):  
Cui Liu ◽  
Qiang Zhang ◽  
Nianqi An ◽  
Jing Wang ◽  
Linlin Zhao ◽  
...  
Keyword(s):  
Real Time ◽  
Living Cells ◽  
Water Soluble ◽  
Real Time Monitoring ◽  
Polythiophene Derivative

Lysosomal ATP imaging in living cells by a water-soluble cationic polythiophene derivative

2016 ◽  
Vol 83 ◽  
pp. 213-220 ◽  
Author(s):  
Bing-Huan Huang ◽  
Zhi-Rong Geng ◽  
Xiao-Yan Ma ◽  
Cui Zhang ◽  
Zhi-Yang Zhang ◽  
...  
Keyword(s):  
Living Cells ◽  
Water Soluble ◽  
Polythiophene Derivative

Octadecyltrichlorosilane Incorporated Alginate Micro-granules as Sustained-Release Carriers for Small Hydrophilic Molecules

2020 ◽  
Vol 17 (4) ◽  
pp. 333-342 ◽  
Author(s):  
Qing Wang ◽  
Bi-min Zhang Newby
Keyword(s):  
Drug Carriers ◽  
Simple Approach ◽  
Water Soluble ◽  
Fickian Diffusion ◽  
Alginate Hydrogel ◽  
Effective Technique ◽  
Hydrophilic Drugs ◽  
Hydrophobic Agent ◽  
Model Drug ◽  
Release Data

Background: Hydrogels are excellent drug carriers, but their inability to retain hydrophilic drugs for a prolonged period of time has greatly limited their usage. Research has mostly focused on intricate designs and manipulations of hydrogels to expand their applications in drug delivery. Objective: In this study, a simple approach by incorporating a hydrophobic agent, octadecyltrichlorosilane (OTS), to alginate hydrogel micro-granules (Alg-Ms), was investigated as an effective technique to prolong the release of small hydrophilic drugs. Methods: Sodium Benzoate (SB), a highly water-soluble antimicrobial and anti-inflammatory compound, was used as a model drug. The presence of hydrophobic OTS impeded swelling of these OTS incorporated Alg-Ms (OTS-Alg-Ms), hence sustaining the release of SB. Results: The release data was fitted with Ritger-Peppas and Peppas-Sahlin models and the results showed that SB released from OTS-Alg-Ms with higher OTS content was mainly controlled by Fickian diffusion; with a lower OTS content, OTS-Alg-Ms swelled more easily, the combined diffusion and swelling led to a faster SB release. Conclusion: Thus, by simply tuning the OTS concentration in the solution where Alg-Ms were briefly submerged in a predefined release period, from hours to a few days, small hydrophilic drugs from these OTS-Alg-Ms could be successfully achieved.

Sign in / Sign up

Export Citation Format

Share Document